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Hydrocodone-Acetaminophen (Vicodin, Lortab)
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• 08/28/25
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Generic Name
hydrocodone/acetaminophen
Trade Name
Vicodin, Lortab, Norco
Indication
management of moderate to severe pain
Action
alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex
Therapeutic Class
opioid Analgesic, allergy, cold and cough remedies, antitussive
Pharmacologic Class
opioid agonists, nonopioid analgesic combinations
Nursing Considerations
• use caution with concurrent use of MAOI – avoid use within 14 days of each other • hypotension – monitor hemodynamics and respirations after administering • may increase ICP use caution with head trauma • Narcan (nalaxone) is the antidote for overdose • DO NOT exceed 4g of acetaminophen per day
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