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Imodium (Loperamide) – Side Effects, Uses, Mechanism of Action, Dosage, Interactions, Warnings
Imodium (Loperamide) – Side Effects, Uses, Mechanism of Action, Dosage, Interactions, Warnings
Imodium, or loperamide, is an over-the-counter antidiarrheal medication used to treat acute, chronic, and travelers' diarrhea, as well as to normalize bowel function post-surgery. It works by binding to opioid receptors in the gut to inhibit acetylcholine and prostaglandins, decreasing peristalsis, and increasing anal sphincter tone, thereby reducing stool frequency and urgency. Common side effects include constipation, dizziness, drowsiness, and nausea, while serious side effects may include severe allergic reactions, abdominal pain, and cardiovascular events. The dosage for adults typically starts at 4 mg followed by 2 mg after each unformed stool, with a maximum of 16 mg per day. For children, dosages are weight-based and require professional supervision. Interactions may occur with CNS depressants, opioids, anticholinergic drugs, HIV medications, and quinidine. Key warnings include avoiding use in bacterial enterocolitis, dysentery, and liver disease, and caution against potential abuse and serious cardiac events. Usage during pregnancy and breastfeeding should be under medical supervision.
#Imodium #Loperamide #WhatisImodiumdrugusedfor? #whatarethesideffectsofimodium #Whatisloperomidedrugusedfor? #whatarethesideffectsofloperomide
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