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Is Pepcid AC really a PMDD cure?

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Reaction! 🎥 This viral video is from a little while back but I wanted to share my insight while it’s #pmddawarenessmonth!⁠

Famotidine (Pepcid AC) is one example of a histamine H2-receptor antagonist, also known as an H2 blocker.⁠

H2 blockers work by reducing the release of stomach acid, but they also block histamine receptors.⁠

So let’s say Nina is suffering from PMDD symptoms like extreme anxiety and depression in her luteal phase.⁠

She tries Pepcid AC and experiences dramatic relief in the lead-up to her period (and posts about it on socials 😋).⁠

This likely means Nina is dealing with elevated histamine levels, and the H2 blocker is acting like a Band-Aid—blocking histamine receptors in the gut (and beyond) to ease her symptoms.⁠

Yay for symptom relief - I’m all about it, especially when PMDD is affecting your relationships and life plans!!⁠

But Nina, honey, do you really want to be on Pepcid AC for two weeks out of every month forever? ⁠

Should you? 👀 There are short- and long-term side effects to think about.⁠

Let’s back up a sec - histamine isn’t the bad guy. It’s actually a compound your body makes naturally, involved in immune responses, digestion, and even brain function.⁠

But when there’s *too much* histamine, that’s when issues can crop up - especially when we’re dealing with menstrual cycles.⁠

Why? Estrogen and histamine have a bi-directional relationship, so if there is a histamine overload situation, it can make your ovulation or luteal phase feel like a minefield.⁠

I’m all about root causes over here, so I believe Nina needs to focus on gut health, inflammation, and her immune system, so estrogen and histamine can finally play nice 💕⁠

Are you in the same boat? Easy first step: ⁠

Here's a link to my free resources in the Fix Your Period Collective! fixyourperiod.com/resources

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