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Is taking 2 doses of combination drug at one time for Migraine safe? - Dr. Pradeep Kumar T J

2 Views • 08/26/25
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Migraine is a condition which is related to vascular disorder of the blood vessels in the brain. It can experience excruciating hemicranial headaches associated with nausea, vomiting and photophobia, which is a discomfort on seeing lights. So they need to be treated again with a combination of drugs which are used to heal acute attacks and also drugs to prevent recurrent attacks. The drugs that are used to treat acute attacks are usually the 5 HT antagonists like sumatriptan, along with that we give a combination of analgesics, anti-nausea drugs, which is a combination domperidone and naproxen, which is the commonest combination that we use. But using this drug immediately reduces the intensity of the headache in half an hour period. In case the patients continue to have pain, there is no harm in taking a repeat dose of drug within 24 hours, a second dosage can be attempted. But at no given point of time, you need to repeat more than 2 drugs in a 24 hour interval. These are the treatment of acute attacks. In terms of preventing the attacks on a regular basis, we use a various drugs and the neurologist and the treating physician would help you to understand the limitation of these drugs, the usage of these drugs and the effects and the side effects of these drugs. So please consult your physician or neurologist for continuous headaches which are frequent, needs to be evaluated further with imaging studies.

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