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Itraconazole in Dermatology - Agent, Mechanism of Action, Use, Side-effects
Hi. With this video, we will discuss the use of Itraconazole in Dermatology and be better prepared for treating our patients. This video is directed towards dermatologists and is not at all advisory for non-medical personnel.
Introduction - 01:51
Pharmacology - 05:58
Pharmacology: Skin - 11:37
Pharmacology: Nails - 13:53
Pharmacology: Hair - 15:30
Mechanism of Action - 17:00
Uses: FDA Approved - 22:25
Uses: Dermatophytes: Onychomycosis - 24:27
Onychomycosis: Pulse - 27:17
Tinea Capitis: 30:08
Tinea Corporis / Cruris and Tinea Pedis - 31:04
Seborrheic Dermatitis - 32:13
Action Non-Dermatophyte - 35:28
Uses: Off-Label - 36:37
Off-Label Uses [Non-fungal] - 38:13
Adverse Events - 40:35
Drug Interactions - 46:10
Pregnancy and Lactation - 49:35
Monitoring - 51:20
Resistance - 52:04
Use With Ant-acids - 54:30
Pellets - 57:15
SUBA-Itraconazole - 01:00:47
Further Reading - 01:04:57
End - 01:06:12
Good articles on Itraconazole:
1. SPORANOX[TM]: Product drug insert.
2. Ghodsi SZ, Abbas Z, Abedeni R. Efficacy of Oral Itraconazole in the Treatment and Relapse Prevention of Moderate to Severe Seborrheic Dermatitis: A Randomized, Placebo-Controlled Trial. Am J Clin Dermatol. 2015;16(5):431-437. doi:10.1007/s40257-015-0133-9
3. Tsai YC, Tsai TF. Itraconazole in the Treatment of Nonfungal Cutaneous Diseases: A Review. Dermatol Ther (Heidelb). 2019;9(2):271-280. doi:10.1007/s13555-019-0299-9
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