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Lactulose Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses
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• 08/20/25
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Lactulose
Generic Name: lactulose
Trade Name: Kristalose
Indication: Constipation, portal-systemic encephalopathy
Action: draws water into the stool and softens stool, inhibits ammonia passing into the colon
Therapeutic Class: laxative
Pharmacologic Class: osmotic
Nursing Considerations
use caution with DM
may cause cramps, abdominal distention, hyperglycemia
assess mental status, ammonia levels, abdominal distention
patient should average 2-3 bowel movements per day
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