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Latest on Current Treatments for Myelofibrosis, Polycythemia Vera, Essential Thrombocythemia

2 Views • 08/19/25
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Top MPN specialist John Mascarenhas, MD of Mt. Sinai, talks about the current, major treatments for MPNs, specifically myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET), including hydroxyurea and newer drugs like ropeginterferon (Besremi). Dr. Mascarenhas also describes common side effects.

Featuring: John Mascarenhas, Dir., Adult Leukemia Program, Tisch Cancer Institute, Mt. Sinai & Professor, Icahn School of Medicine

Full story & transcript → Updated Soon at www.ThePatientStory.com

The interview has only been edited for clarity.

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Contents Of This Video:
00:00 - intro
00:26 - What are current treatment options?
02:00 - Tell us about hydroxyurea
04:25 - Other common MPN treatments & Side Effects
06:10 - How are these different treatments given?
08:00 - Most promising emerging treatments for MPNs
10:15 - Shift in treating MPNs → combinations?
12:09 - Determining myelofibrosis prognosis
13:43 - Determining real-world benefits of fedratinib when ruxolitinib fails
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#ThePatientStory #myeloma #MPN #Cancerexperts #Oncologists #Cancerstories #doctors #Myelofibrosis #PolycythemiaVera #EssentialThrombocythemia

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