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Loop Diuretics EXPLAINED: Mechanism, Side Effects & Clinical Use (USMLE High-Yield)
💊 Loop Diuretics: Mechanism, Side Effects & Clinical Applications
Loop diuretics (e.g., Furosemide, Bumetanide, Torsemide, Ethacrynic Acid) are potent diuretics commonly used in heart failure, pulmonary edema, and hypertension. But how do they work? In this video, we break down the mechanism of action, electrolyte effects, clinical indications, side effects, and contraindications—perfect for medical students, USMLE prep, and healthcare professionals.
What You’ll Learn in This Video:
✔️ How Loop Diuretics Work: Inhibition of the Na+/K+/2Cl- symporter in the loop of Henle
✔️ Electrolyte effects: Hypokalemia, Hypocalcemia, Hypomagnesemia
✔️ Clinical indications: CHF, Pulmonary Edema, Ascites, Hypercalcemia
✔️ Side effects: Ototoxicity, Hypokalemia, Metabolic Alkalosis, Hypotension
✔️ Loop Diuretics vs. Thiazides: Key Differences
✔️ High-yield USMLE & medical exam mnemonics
⏰ Timestamps for Easy Navigation:
0:00 Intro to loop diuretics
0:58 Physiology of the loop of Henle
4:27 Mechanism of loop diuretics
6:39 How hypokalemia affects blood glucose level
15:30 Indications and contraindications of Loop diuretics
17:00 How loop diuretics cause Ototoxicity
💡 Engage With Us:
Question for You: What’s the biggest challenge in understanding diuretics? Let us know in the comments!
Don’t forget to like 👍 this video, subscribe 🔔 to the channel, and share this with fellow students & professionals!
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