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NURTEC ODT / rimegepant for Migraine - What You Need to Know!
Most important Nurtec ODT (rimegepant) facts. Stop your worst migraine with just one pill!
Nurtec ODT (rimegepant) - What You Need to Know
In this edition of The Headache Channel, we take a close look at Nurtec ODT / rimegepant, the exciting new oral dissolving tablet for acute treatment of migraine with or without aura in adults.
Nurtec ODT (rimegepant) is the second example of an exciting new class of migraine treatments called the Gepants. (The other currently available Gepant is Ubrelvy / ubrogepant -- playlist here: https://www.youtube.com/playli....st?list=PL3adjIeYuuK )
For years, people with migraines only had 3 basic choices for acute migraine treatment: triptans (like Imitrex / sumatriptan, Maxalt / rizatriptan, etc.), ergots (like Cafergot) and dihydroergotamine / DHE (like D.H.E. 45). These helped a lot of people over the years, but had a lot of shortcomings. They often didn't get rid of all the migraine headache pain. They may have helped pain, but not the other disabling symptoms of migraine like photophobia / light sensitivity, nausea, or phonophobia (sound sensitivity). They may have helped for a couple of hours, but then the pain came back. For a lot of people the side effects of the traditional acute migraine treatments were worse "headaches" than the migraine itself: chest tightness, jaw pain, fatigue, nausea. And traditional treatments are contraindicated / off limits for people who have heart disease, strokes, TIAs, high blood pressure, migraine with brainstem aura or hemiplegic migraine.
Nurtec ODT is an acute migraine treatment that works by blocking CGRP receptors, turning down and turning off the migraine attack.
Nurtec is different from the injectable CGRP-blockers used for migraine prevention (Aimovig / erenumab, Ajovy / fremanezumab, Emgality / galcanezumab, and Vyepti / epitinezumab).
A single dose of Nurtec starts working in 60 minutes. By 2 hours 60% of people have pain relief and 40% of people can return to their daily activities. 86% of people who took Nurtec needed no migraine rescue treatment for 24 hours.
The most common side effect of Nurtec is nausea. Other side effects are possible.
Nurtec ODT is not for women who are pregnant or breastfeeding, and is not for people with very bad kidneys or livers. Nurtec ODT is also not for people who are taking certain medicines that increase or decrease levels of Nurtec ODT in the body. Nurtec ODT is also not for people who are allergic to rimegepant or to any of the inactive ingredients. Nurtec ODT is made with gelatin from fish, so it's not vegan. It's also not specifically halal or kosher.
Recurrent sinus headache without fever is migraine until proven otherwise.
Has anyone out there tried Nurtec ODT off label for cluster headache, trigeminal neuralgia, hemicrania, trigeminal autonomic cephalalgia? Let us know your experience!
The Headache Channel is for information and entertainment purposes only. If you need medical advice, please see your physician.
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