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Orexin Blocking Sleep Medications - Belsomra - Dayvigo - Quviviq

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Main Chapters:
00:00 Intro - Orexin Blocking Sleep Medications - Belsomra - Dayvigo - Quviviq
00:11 Take home message
01:13 What is the Orexin System?
05:19 Medications Affecting the Orexin System
09:21 Other Types of Sleep Medications
14:32 Sleep and Mental Health Conditons
17:15 Conclusion and Outro

Belsomra - Suvorexant
Dayvigo - Lemborexant
Quviviq - Daridorexant

Belsomra (suvorexant) entered the US sleep-aid market almost a decade ago, and was recently joined by Dayvigo (lemborexant) and Quviviq (daridorexant).
All of these agents work to block orexin receptors in the brain, a distinctively different mechanism than other sleeping pills.

Despite several distinct advantages over other classes of sleeping agents, sales have not been spectacular. But recent discoveries, particularly a suggestion that suvorexant may reduce the amyloid Beta plaques and Tau fibrillary tangles that are hallmarks of Alzheimer's Dementia has driven up attention.

Experts think that these agents may also have a role in treating depression, anxiety and ADHD.

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Free link to my Medium Article on Orexin Blocking Sleep Medications:
https://medium.com/invisible-i....llness/our-best-inso

Follow https://dockruse.medium.com on Medium for hundreds of full length articles on this subject and more!
Access to other Medium articles requires paid membership.
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Full Chapter list:
00:00 Intro - Orexin Blocking Sleep Medications - Belsomra - Dayvigo - Quviviq
00:11 Take home message
01:13 What is the Orexin System?
02:41 What is Orexin?
05:19 Medications Affecting the Orexin System
05:35 Modafinil (Provigil) / Armodafinil (Nuvigil)
06:23 DORA Medications (Dual Orexin Receptor Antagonist)
09:21 Other Types of Sleep Medications
09:37 Benzodiazepines
11:33 NonBenzodiapzepines (Z-drugs)
13:04 Comparing with the DORA Medications
14:32 Sleep and Mental Health Conditons
17:15 Conclusion and Outro

Streamed live June 14, 2023

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Psychiatrist, neuroscientist, and author John Kruse, MD, PhD presents practical, actionable, well-researched information about treatment options that scientists and clinicians recommend for adult ADHD and other mental health conditions. Subscribe if you're curious about how neuro-atypical brains can optimize their functioning in our shared, and somewhat strange, world.

Dr. Kruse has posted talks in both the "live" and the "video" sections of this channel. Thumbnails on ADHD topics have a pink background, and those on more general mental health topics have a purple background. A small collection of ADHD-Trump videos have an orange background.

You're welcome to email him with topics you want discussed or people you think he should interview.

[email protected]

#health #mentalhealth #sleep #orexin

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