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Salk scientists develop drug that slows Alzheimer's
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• 08/29/25
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Findings may lead to first therapeutic drug to treat advanced Alzheimer's
LA JOLLA, CA -- A drug developed by Scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, published in the journal Alzheimer's Research and Therapy, may pave the way to a new treatment for Alzheimer's disease in humans.
"J147 is an exciting new compound because it really has strong potential to be an Alzheimer's disease therapeutic by slowing disease progression and reversing memory deficits following short-term treatment," says lead study author Marguerite Prior, a research associate in Salk's Cellular Neurobiology Laboratory.
Despite years of research, there are no disease-modifying drugs for Alzheimer's. Current FDA-approved medications, including Aricept, Razadyne and Exelon, offer only fleeting short-term benefits for Alzheimer's patients, but they do nothing to slow the steady, irreversible decline of brain function that erases a person's memory and ability to think clearly.
Learn more about the study at: http://www.salk.edu/news/press....release_details.php?
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