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Side effects, interactions and precautions of Buspirone

2 Views • 08/17/25
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Buspirone hcl (buspar) is used for anxiety and it can cause mild side effects compared with benzos. It is available as 5 mg and 10 mg tablets.

It is a 8-Azaspirodecane and it is metabolized mainly by CYP3A4 system resulting in number of possible drug interactions. Drugs like itraconazole, SSRIs, TCAs and haloperidol inhibit this enzyme resulting in significant drug interactions. Grape fruit juice can also inhibit the metabolism of buspirone. On the other hand, drugs such as carbamazepine and rifampicin can induce the enzyme resulting in increased metabolism of buspirone. Side effects of this mainly include headache, dizziness and drowsiness in the patients.

#buspironesideeffects
#buspirone
#buspironeforanxiety

0:00 Introduction
0:06 Chemical nature of Buspirone
1:41 Mechanism of action
2:38 Where it is used?
3:26 Side effects
4:18 Metabolism
5:04 Drug interactions
6:20 Contraindications
7:22 Precautions

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