Drug-resistant hypertension is defined as suboptimal blood pressure control despite the treatment with at least three blood pressure-lowering drugs. Up until now, choosing a 4th add-on drug in these patients has been a doctor’s subjective preference more than a scientifically sound decision. Well, these times are over because Bryan Williams and colleagues found out what you should do in these patients in the so-called REVERT-2 trial, which was published in the Lancet in September 2015. Watch the above video to learn all about it.

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