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Surfactant Laxatives (Docusate) | Stool softeners
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Video Summary:
Surfactant Laxative/stool softeners:
Drugs: Docusate
Mechanism of action: Decrease surface tension of stool which allows mixing of water with stool. This makes the stool soft which is easy to pass It takes 1-3 days to work.
Use: prophylaxis of constipation and decrease straining at defecation.
Adverse events: nausea, cramp, abdominal pain, hepatotoxicity on prolonged use.
It disrupts the mucosal barrier and increases absorption of many non-absorbable drugs i.e. liquid paraffin so both should not be used together.
● Other drugs for constipation:
• Bulk Forming Laxatives: https://youtu.be/rQf8sYy_vTI
• Osmotic Purgatives: Lactulose, Polyethylene Glycol Etc: https://youtu.be/coTYF7yNuS4
• Lubricant Laxatives/Liquid Paraffin: https://youtu.be/2vWv_V66ozY
• Stimulant Laxatives / Irritant Laxatives: https://youtu.be/yFQBRljaOMI
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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.
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