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Warfarin (Coumadin) Nursing Considerations
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• 08/29/25
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Download the cheat: https://bit.ly/50-meds View the lesson: Generic Name warfarin Trade Name Coumadin Indication
venous thrombosis, pulmonary embolism, A-fib, myocardial infarction
Action
disrupts liver synthesis of Vitamin K dependent clotting factors
Therapeutic Class
Anticoagulant
Pharmacologic Class
coumarins
Nursing Considerations
• contraindicated with bleeding, severe hypertension • can cause bleeding • aspirin and NSAIDs can increase risk of bleeding • azole antifungals increase effects of warfarin • cimetadine(Tagamet) increases warfarin levels • obtain full history of supplements and herbs • large amounts of vitamin K may antagonize effects of warfarin • assess for signs of bleeding • therapeutic levels: PT 1.3-1.5, INR 2.5-3.5 • instruct patient to report any signs of bleeding • patient should not drink alcohol • bleeding times need to be monitored frequently • vitamin K is antidote
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