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What is Austedo? What is Austedo used for? Uses, Dosage and Side Effects!
What is Austedo? What is Austedo used for? Uses, Dosage and Side Effects!
Learn all about Austedo, its uses, and how it works! Explore symptoms, side effects, and dosage tips. Share your experiences in the comments!
## Introduction to Austedo
- **Medication Overview**: Austedo, also referred to as deutetrabenazine, is primarily used to treat chorea, which involves sudden involuntary movements associated with Huntington's disease. It also treats symptoms of tardive dyskinesia (TD), a nervous system disorder that causes repetitive and uncontrolled muscle movements, typically in areas such as the face.
- **Mechanism of Action**: Classified as a vesicular monoamine transporter 2 (VMAT2) inhibitor, Austedo functions by altering the activity of certain neurotransmitters in the brain that affect nerve and muscle function. This is achieved by reducing the amount of chemical messenger between nerve cells, thereby alleviating unwanted movements.
## How Austedo Works
- **Neuronal Communication**: Motor function is regulated in the brain by neurons that communicate through chemical messengers known as neurotransmitters. Movement disorders like Huntington's disease and tardive dyskinesia arise from disruptions in this communication system.
- **Role of VMAT2 Inhibitors**: VMAT2 controls neurotransmitter storage and release in nerve cells. Austedo works by blocking VMAT2, decreasing the availability of neurotransmitters, which ultimately reduces involuntary body movements.
## Dosage and Administration
- **Standard Dosage Instructions**: The initial dose for Austedo is 6 mg taken twice daily, totaling 12 mg per day. The dosage may be increased by increments of 6 mg per day at weekly intervals, depending on the reduction of symptoms and patient tolerability, with a maximum dose of 48 mg per day.
- **Austedo XR**: The extended-release version, Austedo XR, starts with an initial dose of 12 mg once daily, which can also be increased weekly by 6 mg increments up to a maximum of 48 mg per day. It can be taken with or without food, and tablets should be swallowed whole.
## Important Precautions and Side Effects
- **Contraindications and Precautions**: Patients allergic to deutetrabenazine, those with untreated or uncontrolled depression, or those who have recently used certain other medications, should not use Austedo. It is important to adhere to other medication restrictions such as MAO inhibitors within certain time frames.
- **Potential Side Effects**: Possible side effects include allergic reactions, suicidal thoughts, and symptoms indicative of disease progression. Patients and caregivers must be vigilant for changes in mood or behavior and consult healthcare providers regularly to monitor treatment progress.
00:00 Introducing Austedo
00:53 How It Works
01:39 Usage Precautions
02:44 Dosing Information
04:27 Side Effects
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