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What Is Glucosamine And Why You Need It? Functions, Recommendations, Side Effects, Why it Works

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Glucosamine is a natural compound found in cartilage, the tough, flexible tissue that cushions your joints. It's an amino sugar that plays a crucial role in maintaining the structure and function of cartilage and other connective tissues.
In supplement form, glucosamine is commonly harvested from the shells of shellfish (like shrimp, crabs, and lobsters) or can be produced in a lab, including plant-based versions derived from corn.
People often take glucosamine supplements, especially glucosamine sulfate, to address joint health concerns, particularly osteoarthritis. It's thought to help by:
Supporting cartilage health: As a building block of cartilage, it's believed to aid in the repair and regeneration of cartilage tissue.
Relieving osteoarthritis symptoms: Some research suggests it may help reduce joint pain, stiffness, and improve physical function, particularly in knee osteoarthritis. However, research results have been mixed, and some experts believe the benefits might be due to a placebo effect.
Reducing inflammation: Glucosamine may have anti-inflammatory properties, especially when taken with chondroitin.
While generally considered safe for most adults, it's important to be aware of potential side effects, which can include mild gastrointestinal issues. Those with shellfish allergies should be cautious as most supplements are derived from shellfish. Also, individuals on blood thinners like warfarin, or those with asthma or glaucoma, should consult a doctor before taking glucosamine.

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