Is my medicine causing dementia? Which medications cause dementia??
We take medication expecting it to make us better or make us feel better. The last thing we want is to take a medication for one thing and have it make something get worse.
(See below for the full list)
If you are taking any of the Anti-Cholinergics as a long-term medication, then that is exactly what might be happening. You might be taking something to help you sleep or to lessen muscle spasms, and what it might be doing in the background is increasing your risk of developing dementia. Do you take any of the medications I discuss?

Here is the list, it is not complete, but contains all the most common drugs:
Amitriptyline (Elavil) [high AC activity]
Atropine [high AC activity]
Benztropine (Cogentin) [high AC activity]
Chlorpheniramine (Actifed, Chlor-Trimeton, etc.) [high AC activity]
Chlorpromazine (Thorazine) [high AC activity]
Clomipramine (Anafranil) [high AC activity]
Clozapine (Clozaril) [high AC activity]
Cyclobenzaprine (Amrix, Fexmid, Flexeril) [moderate AC activity]
Cyproheptadine (Periactin) [moderate AC activity]
Desipramine (Norpramin) [high AC activity]
Dexchlorpheniramine (Polaramine) [high AC activity]
Dicyclomine (Bentyl) [high AC activity]
Diphenhydramine (Advil PM, Aleve PM, Benadryl, Tylenol PM, Unisom, etc.) [high AC activity]
Doxepin (Adapin, Silenor, Sinequan) [high AC activity]
Fesoterodine (Toviaz) [moderate to high AC activity]
Hydroxyzine (Atarax, Vistaril) [high AC activity]
Hyoscyamine (Anaspaz, Levbid, Levsin, Levsinex) [high AC activity]
Imipramine (Tofranil) [high AC activity]
Meclizine (Antivert, Bonine) [high AC activity]
Mepenzolate (Cantil) [high AC activity]
Nortriptyline (Pamelor) [high AC activity]
Olanzapine (Zyprexa) [high AC activity]
Orphenadrine (Norflex) [high AC activity]
Oxybutynin (Ditropan, Oxytrol) [high AC activity]
Paroxetine (Brisdelle, Paxil) [low AC activity]
Perphenazine (Trilafon) [high AC activity]
Prochlorperazine (Compazine) [moderate AC activity]
Promethazine (Phenergan) [high AC activity]
Protriptyline (Vivactil) [high AC activity]
Pseudoephedrine HCl [moderate to high AC activity]
Scopolamine (Transderm Scop) [high AC activity]
Thioridazine (Mellaril) [high AC activity]
Tolterodine (Detrol) [high AC activity]
Trifluoperazine (Stelazine) [high AC activity]
Trimipramine (Surmontil) [high AC activity]

Other drugs which have AC Activity and could pose a risk:
Alprazolam (Xanax) [low to moderate AC activity]
Amantadine (Symmetrel) [low AC activity]
Baclofen [moderate AC activity]
Brompheniramine [high AC activity]
Carbamazepine (Tegretol) [moderate AC activity]
Carbinoxamine (Arbinoxa) [moderate to high AC activity]
Carisoprodol (Soma) [moderate AC activity]
Cetirizine (Zyrtec) [moderate AC activity]
Cimetidine (Tagamet) [moderate AC activity]
Clemastine (Tavist) [moderate to high AC activity]
Clidinium & chlordiazepoxide (Librax) [low to moderate AC activity]
Clorazepate (Tranxene) [low AC activity]
Codeine [low AC activity]
Colchicine [low AC activity]
Darifenacin (Enablex) [moderate to high AC activity]
Digoxin (Lanoxicaps, Lanoxin) [low AC activity]
Dimenhydrinate (Dramamine, Gravol, etc) [high AC activity]
Diphenoxylate/atropine (Lomotil) [moderate to high AC activity]
Disopyramide (Norpace) [low to moderate AC activity]
Flavoxate (Urispas) [moderate AC activity]
Fluphenazine (Prolixin) [moderate AC activity]
Furosemide (Lasix) [low AC activity]
Hydrochlorothiazide (Esidrix, Dyazide, HydroDIURIL, Maxzide & others) [low AC activity]
Loperamide (Imodium) [moderate AC activity]
Loratadine (Alavert, Claritin) [moderate AC activity]
Loxapine (Loxitane) [moderate AC activity]
Maprotiline [low to moderate AC activity]
Meperidine (Demerol) [moderate AC activity]
Methocarbamol (Robaxin) [moderate AC activity]
Methotrimeprazine (Nozinan) [moderate AC activity]
Nifedipine (Adalat, Procardia) [low AC activity]
Olanzapine (Zyprexa) [moderate AC activity]
Orphenadrine (Norflex) [moderate AC activity]
Quetiapine (Seroquel) [moderate AC activity]
Procyclidine (Kemadrin) [moderate AC activity]
Propantheline (Pro-Banthine) [moderate to high AC activity]
Ranitidine (Zantac) [low AC activity]
Solifenacin (VESIcare) [low to moderate AC activityy]
Thiothixene (Navane) [high AC activity]
Tizanidine (Zanaflex) [high AC activity]
Tramadol (Ultram) [low AC activity]
Trihexyphenidyl (Artane) [high AC activity]
Trospium (Sanctura, Spasmex) [high AC activity]

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Ken D Berry, MD is a Board Certified Family Physician. He has been practicing Family Medicine in rural Tennessee for almost 2 decades, having seen over 25,000 patients in his career so far.
Consult your doctor. Don't use this video as medical advice.

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