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ZOPICLONE (IMOVANE): Review, Uses, Side Effects, Mechanism of Action
ZOPICLONE (IMOVANE): Review-Uses-Side Effects- Mechanism of Action- Withdrawal- For Insomnia Anxiety
What is zopiclone used for?
Zopiclone is a type of sleeping pill that can be taken to treat bad bouts of insomnia. It helps you fall asleep more quickly, and also helps stop you waking up during the night. Zopiclone comes as tablets.
How does zopiclone work?
Zopiclone boosts the effectiveness of a chemical in the brain called gamma-aminobutyric acid (GABA).
GABA blocks transmission across nerves in the brain and has a calming effect.
Is zopiclone good for anxiety?
Zopiclone reduces day time anxiety; has low frequency of rebound insomnia.
What are the side effects of taking Zopiclone?
SIDE EFFECTS: Daytime drowsiness, dizziness, lightheadedness, bitter taste, dry mouth, headache or stomach upset may occur the first few days as your body adjusts to the medication. If any of these effects continue or become bothersome, inform your doctor.
Is zopiclone a narcotic?
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine used to treat difficulty sleeping. Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone.
What does zopiclone do to the brain?
Zopiclone is a type of medicine called a non-benzodiazepine hypnotic. It acts in the brain to aid sleep. Zopiclone works by increasing the activity of a neurotransmitter called GABA in the brain.
Does zopiclone knock you out?
Mental effects Zopiclone helps you sleep, though users who manage to stay awake on it can feel drowsy and calm.
Is it okay to take Zopiclone every night?
You can take zopiclone with or without food. It's important to take it exactly as your doctor has told you. You could be asked to take a tablet on only 2 or 3 nights each week, rather than every night.
Who should not take Zopiclone?
Zopiclone 7.5mg tablets is contraindicated in patients with myasthenia gravis, respiratory failure, severe sleep apnoea syndrome, severe hepatic insufficiency and those people with a hypersensitivity to zopiclone or to any of the excipients. As with all hypnotics, Zopiclone 7.5mg tablets should not be used in children.
Why is zopiclone banned in US?
Lunesta 3 mg had an impairing effect almost as large as zopiclone 7.5 mg, a similar insomnia drug. Zopiclone, which is not approved in the United States, causes consistent psychomotor impairment such that it is often used as a positive control in driving impairment studies.
Does zopiclone make you tired the next day?
Precautions – while you are taking zopiclone
Extra care is needed when taking zopiclone because it can cause sleepiness and affect your concentration the next day.
Is zopiclone linked to dementia?
According to manufacturers' literature, memory loss has been reported shortly after taking zopiclone. The incidence of these reactions is known to be rare and may be more likely to occur in elderly patients.
What is a good substitute for Zopiclone?
Eszopiclone, a stereoisomer of zopiclone, is a non-benzodiazepine hypnotic agent of the cyclopyrrolone family. Similar to zopiclone, eszopiclone is a synthetic compound shown to be effective in treating insomnia
What is the maximum zopiclone you can take?
Zopiclone is typically prescribed in the range of 5 mg to 7.5 mg daily and at 3.75 mg daily for the elderly. While zopiclone is a highly effective sleep aid, there is controversy about the extent of its addiction potential.
How long does Zopiclone 3.75 take to wear off?
The lowest effective dose should be used. Zopiclone should be taken in a single dose and not re-administered during the same night. Treatment with zopiclone should be as short as possible.
How many hours sleep with Zopiclone?
Zopiclone can affect your recent memory, especially if you do not go to bed just after taking it, or if your sleep gets interrupted. Make sure that you can get seven to eight hours of uninterrupted sleep if you are going to take zopiclone.
What happens when you stop taking Zopiclone?
Stopping zopiclone suddenly may cause withdrawal side effects. After taking zopiclone for insomnia, you may have difficulty sleeping (rebound insomnia) for the first few nights after you stop taking it.
What are the side effects of long term use of zopiclone?
Over the long term, zopiclone abuse can result in symptoms including chest pain; heart palpitations; nightmares; amnesia; abdominal pain; constipation; sinusitis; sore throat; dry mouth; lethargy; back pain; flu-like symptoms
Is it safe to take Zopiclone long term?
Zopiclone and some benzodiazepines, such as temazepam and triazolam, are indicated for the short-term treatment of insomnia. Long-term use of these medicines should be avoided
What drugs interact with Zopiclone?
alcohol.
amiodarone.
anti-anxiety medications (e.g., alprazolam, clonazepam, lorazepam)
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