dexamethasone for covid has been a biggest Boon now trending, but still there are Dexamethasone side effects you might not aware, Look at this video about dexamethasone injection

If you are searching for the side affects of Dexa Metha Sone then you might already aware of this drug

Low doses of the steroid #dexamethasone can reduce deaths by one-third in severely affected #COVID19 patients, according to the performance of the inexpensive drug in more than 2,100 people

The low-dose steroid treatment dexamethasone is a major breakthrough in the fight against the deadly virus

And it could be of huge benefit in poorer countries with high numbers of #Covid-19 patients.

About 19 out of 20 patients with coronavirus recover without being admitted to the hospital.

The cost for dexamethasone injectable solution (4 mg/mL) is around $25 which is around 1900 Rupees in India

But still there are few side affects on using this drug

DEXAMETHASONE is a steroid which can damage your liver and weaken your immune system or may cause severe irreversible side effects.

It is only effective on patients with alveolar inflammation or those who are on ventilator,

DEXAMETHASONE have no effect on mild or asymptomatic COVID-19 individuals. Therefore it should only be prescribed in serious conditions or as prescribed by your consultant.

Dexamethasone is a steroid called glucocorticoid. Dexamethasone sodium phosphate injection ip is available in 2ml/4ml/8ml strength. Dexamethasone injection is long acting having half-life of 36 hours.
Dexamethasone injection brand names are
Dexona injection
Dexa injection
Decadron injection
Decdan injection etc…
Dexamethasone can be administered I.V / I.M.
Dexamethasone injection is used in the treatment of skin allergic reactions, breathing problems, asthma, vomiting, bee bitr, insect bite, minor poisoning etc…
Dexamethasone injection contraindications are
Cannot use in pregnancy and breastfeeding mother etc…
We also discuss about dexamethasone sodium phosphate ip injection
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Join me in this video as we discuss more about Dexamethasone(Decadron/Dexasone), It's uses, warnings, interactions and side effects.

Can we take Dexona and Practin Tablet without Side effects to gain weight? this question explained here

#Dexona #practintablet #weightgain
#Tabletforweightgain

Time stamp -
00:00 Introduction
00:21 What is Dexona and Practin Tablet
00:49 Side effects of dexona
01:31 Prcatin tablet use
02:32 Dexona use

Dexamethasone is a synthetic glucocorticoid (adrenocortical hormone)
Corticosteroids are hormones that are found naturally in your body that help to keep you healthy and well.

Video Content:
0:00 Dexamethasone tablets
0:33 Indications
0:45 How to use
1:20 Contraindications
1:45 Precautions
2:23 Side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#dexamethasone #immunesystem #medicine

Dexamethasone is a potent corticosteroid medication used to treat a wide range of medical conditions, from asthma and arthritis to certain types of cancer. In this informative video, we'll dive into the various uses, dosage, and potential side effects of this powerful drug.

We'll cover how Dexamethasone works, the conditions it's commonly prescribed for, and the appropriate dosage guidelines. Importantly, we'll also explore the possible side effects, both short-term and long-term, so you can make an informed decision with your healthcare provider.

Understanding the risks and benefits of Dexamethasone is crucial for anyone considering or currently using this medication. Watch this video to learn more and share it with anyone who may find the information useful.

#Dexamethasone #Corticosteroid #MedicationSideEffects #HealthInformation

OUTLINE:

00:00:00 Introduction to Dexamethasone
00:00:35 Correct Usage of Dexamethasone
00:00:59 Side Effects of Dexamethasone
00:01:37 Recap and Conclusion

9 Top Uses & Side Effects of Dexamethasone #pancreatitis #highbloodpressure #dexamethasone

In this video it is defined that
Dexamethasone is a corticosteroid medication used to treat a wide range of conditions due to its anti-inflammatory and immunosuppressive effects. It comes in various forms, including tablets.
Uses of Dexamethasone Tablets
1. Inflammatory Conditions
Rheumatoid arthritis
Lupus
Inflammatory bowel disease (e.g., Crohn’s disease, ulcerative colitis)
Severe allergies or asthma
2. Autoimmune Disorders
Multiple sclerosis
Certain types of vasculitis
3. Cancer Treatment
As part of chemotherapy regimens (e.g., for leukemia, lymphoma, or multiple myeloma)
To reduce brain swelling (edema) caused by brain tumors
4. Endocrine Disorders
Adrenal insufficiency (as a temporary replacement for cortisol)
Congenital adrenal hyperplasia
5. Respiratory Conditions
Severe asthma attacks
Chronic obstructive pulmonary disease (COPD) exacerbations
Croup (in children)
6. Severe Allergic Reactions
As a supportive treatment when antihistamines or epinephrine alone are not sufficient
7. Cerebral Edema
Reducing swelling in the brain due to injury, tumor, or surgery
8. COVID-19 Treatment
Used in hospitalized patients with severe COVID-19 to reduce inflammation and immune response in the lungs
9. Nausea and Vomiting (Chemotherapy-Induced)
Often used in combination with other antiemetics
Important Notes
• Should be taken exactly as prescribed.
• Long-term use can lead to side effects like osteoporosis, high blood sugar, increased risk of infections, mood changes, and others.
• Tapering is important when discontinuing after prolonged use to avoid adrenal insufficiency.
Common Dexamethasone side effects:
Which may include:
• fluid retention (swelling in your hands or ankles);
• increased appetite;
• mood changes, trouble sleeping;
• skin rash, bruising or discoloration;
• acne, increased sweating, increased hair growth;
• headache, dizziness;
• nausea, vomiting, upset stomach;
• changes in your menstrual periods; or
• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
Dexamethasone Serious Side effects
Get emergency medical help if you have signs of an allergic reaction to dexamethasone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
• muscle tightness, weakness, or limp feeling;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• shortness of breath (even with mild exertion), swelling, rapid weight gain;
• severe depression, unusual thoughts or behavior;
• a seizure (convulsions);
• bloody or tarry stools, coughing up blood;
• fast or slow heart rate, weak pulse;
• pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting;
• low potassium level - leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling; or
• increased blood pressure - severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed.
Dexamethasone can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using dexamethasone.

Video transcript :-

Dexamethasone belongs to the drug class of corticosteroids, which are potent anti-inflammatory and immunosuppressant medications.
It is used to treat a wide range of disease conditions, including the following.
Inflammatory disorders such as rheumatoid arthritis, systemic lupus erythematosus, dermatitis, inflammatory bowel disease, asthma, and chronic obstructive pulmonary disease.
Allergic reactions, including allergic rhinitis, allergic dermatitis, and drug reactions.
Autoimmune diseases like multiple sclerosis, and autoimmune hepatitis.
Certain types of cancers such as leukemia, lymphoma, and multiple myeloma, to reduce inflammation and suppress the immune response.
To reduce swelling in the brain caused by tumors, injury, or surgery.
Endocrine disorders such as adrenal insufficiency and congenital adrenal hyperplasia.
To prevent nausea and vomiting in patients who undergo chemotherapy.
To induce fetal lung maturation and reduce the risk of respiratory distress syndrome in premature infants.
Dexamethasone, like other corticosteroids, exerts its effects by binding to intracellular glucocorticoid receptors.
Once bound, the dexamethasone-receptor complex translocates into the cell nucleus, where it acts as a transcription factor.
This complex regulates gene expression by either enhancing or suppressing the transcription of specific target genes.
The net result is a wide range of physiological effects, including anti-inflammatory, immunosuppressive, anti-allergic, and metabolic actions.
Dexamethasone inhibits the production of inflammatory mediators, such as prostaglandins and leukotrienes, and suppresses the activity of various immune cells, such as T cells and macrophages.
Additionally, it alters the expression of proteins involved in glucose metabolism, leading to increased blood glucose levels.
Dexamethasone is well-absorbed after oral administration, with peak plasma concentrations reached within 1-2 hours.
It can also be administered via intramuscular or intravenous routes for rapid onset of action.
Metabolism of dexamethasone primarily occurs in the liver, primarily via the enzyme cytochrome P450.
Metabolites are mostly inactive and undergo further conjugation before excretion.
Dexamethasone and its metabolites are primarily excreted via the kidneys.
Common adverse effects of dexamethasone include the following.
Immunosuppression, which increases the susceptibility to various infections.
Glucose Intolerance and Hyperglycemia.
Fluid and Electrolyte Imbalances.
Osteoporosis and Bone Fractures.
Gastrointestinal Effects, including gastric irritation, peptic ulcers, and pancreatitis.
Psychiatric Effects, including insomnia, mood swings, anxiety, depression, and cognitive changes such as memory impairment and confusion.
Ocular Effects such as increased intraocular pressure, leading to glaucoma or exacerbating pre-existing glaucoma.
It may also induce cataract formation with long-term use.
Skin Changes such as skin thinning, easy bruising, delayed wound healing, and exacerbation of existing skin conditions such as acne and rosacea.
Weight Gain.
Musculoskeletal Effects like muscle weakness, myopathy, and muscle wasting, particularly with prolonged use.
Endocrine Effects, including menstrual irregularities, hirsutism, and adrenal suppression.
In children, it can inhibit growth and development.
Cardiovascular Effects such as hypertension, myocardial infarction, and stroke.
Hematological effects such as leukopenia and thrombocytopenia.
Metabolic effects such as elevated blood cholesterol and triglycerides and hypokalemic metabolic alkalosis.
Contraindications for dexamethasone therapy include the following.
Systemic Fungal Infections.
Live Vaccines.
Hypersensitivity to dexamethasone
Systemic Viral Infections.
Active Peptic Ulcer Disease.

Uncontrolled Hypertension.
Diabetes.
Ocular Herpes Simplex.
Active Tuberculosis.
And Recent Myocardial Infarction.

#dexamethasone #dexa #medtoday #medicaleducation #pharmacology
#medicaleducation #medicalknowledge #health #healtheducation

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Dexamethasone (decadron) is a synthetic corticosteroid with anti-inflammatory and immunosuppressant activities. This drug has alpha methyl substitution at 16th position and fluorine group at 9th position.

0:00 Introduction
0:08 DEXAMETHASONE
3:36 Chemical nature
7:47 Precautions
11:00 Side effects
11:46 How it is given?