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Opioids, sometimes called narcotics, are a group of drugs that act on the central nervous system to produce morphine-like effects such as pain relief and euphoria. This pharmacology lecture covers topics such as nociceptive pain pathway, role of glutamate, substance P, and calcitonin gene–related peptide (CGRP) in pain processing, endogenous opioids (enkephalins, endorphins, dynorphins), NMDA, AMPA, NK-1, CGRP receptors, opioid receptors (mu, delta, kappa) mechanism of action and side effects of narcotic drugs, development of opioid tolerance and addiction, partial mu-receptor opioid agonist and antagonist. Drugs mentioned include; Morphine, Fentanyl, Hydrocodone, Hydromorphone, Methadone, Meperidine, Oxycodone, Oxymorphone, Buprenorphine, and Naloxone.

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0:00 Nociceptive pain pathway
0:54 Neurotransmission of pain signal
2:57 Endogenous opioids & opioid receptors
4:32 Synthetic opioids
5:29 Side effects
7:19 Opioid addiction
8:50 Buprenorphine
10:02 Opioid antagonist - Naloxone

Sevredol contains the active ingredient morphine, which is used to relieve severe pain in cases such as severe injury, following a surgery, cancer, and heart attack. Morphine is also used in terminal illness.

Morphine is an opioid, also known as an analgesic opioid, meaning that it’s a painkiller that acts on the opioid system in the brain. Opioid analgesics work by mimicking the action of compounds found in the brain and spinal cord called endorphins. Endorphins promote pain relief and mental relaxation when released.

Morphine acts as a endorphin by acting on the sites where these endorphins send nerve messages. This dampens pain signals, relieving pain and increasing relaxation.

If you would like to find out more visit:
http://www.lynchspharmacy.com/....medicine/sevredol-mo
http://www.lynchspharmacy.com

You can also visit Lynch's Pharmacy in Broadale, Maryborough Hill, Cork.

You should always consult your doctor if you have any concerns before taking any medication.

Thank you for watching!

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Today’s video is all about opioid analgesics for Nursing Students and NCLEX Review.

Analgesics are a drug class that reduce pain or fever. Opioids are a type of analgesic that binds to receptors in the brain and spinal cord, changing a patient’s perception of pain.

As a nurse, you should know how opioids (like fentanyl) can cause addiction, respiratory depression, and apnea.

Free Pharmacology NCLEX Prep Download: https://simplenursing.com/pharmacology/utm_source=youtube.com&utm_content=opioids

Key Moments:
0:00 - Introduction
0:33 - Overview of Opioids and CNS Depression
1:18 - Common Opioids and Memory Tricks
1:46 - Killer Side Effects and Narcan Use
3:02 - Sedation and Respiratory Depression
4:37 - Priority Nursing Care (AIMS)
5:09 - IV Administration of Opioids
6:00 - High-Risk Patients for Opioid Use
7:00 - Short-Term and Long-Term Side Effects
8:24 - PCA Pumps and Nursing Care
9:41 - Fentanyl: Potency and Patient Teaching
11:00 - Fentanyl Patch Application and Guidelines

#NCLEX #pharmacology #Opioids #nsaids #narcan #tylenol #ibuprofen #painmedicine #aspirin #nclexreview #nclexstudyguide #nursing #nursingexam #nursingstudent

Apomorphine is used to treat episodes in people with advanced Parkinson's disease. However, this recent study shows that this medication is a new oral medication shown to be effective in the treatment of erectile dysfunction. Watch as Dr. Rena Malik explains everything you need to know about apomorphine, and how it really works.

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▶️Chapters:
00:00 Introduction
00:48 Apomorphine
01:53 How apomorphine works
06:00 Nitrates
07:40 Adverse Effects
09:24 Takeaways

Sequential administration enhances the effect of apomorphine SL in men with erectile dysfunction: https://www.nature.com/articles/3900831
The Role of Apomorphine SL in the Treatment of Erectile Dysfunction https://www.sciencedirect.com/....science/article/abs/
Letter Urging Rejection of Apomorphine (Uprima): https://www.citizen.org/articl....e/letter-urging-reje
Sublingual apomorphine for the treatment of erectile dysfunction: https://www.tandfonline.com/do....i/epdf/10.1517/13543

Watch the video till the end and let me know your thoughts in the comments.
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Rena Malik, MD is a urologist and pelvic surgeon on youtube to educate people about all things urology including erectile dysfunction, how to increase testosterone, problems with sex, premature ejaculation, urinary leakage, or incontinence, overactive bladder, urinary tract infections, prostate issues and more.

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Welcome back to my channel. If you are new here, I am Neil and I create Beauty&Makeup, Inspirational, Educational, and Reaction videos.

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Learn morphine side effects with mnemonics

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Morphine side effects mnemonics
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- This is lesson n# 53 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Morphine (Maracex, Oramorph, Sendolor): What is Morphine Used For, Uses, Dosage, Side effects Precautions and mechanism of action

- In less than 5 minutes you'll learn:

- What is Morphine (Maracex, Oramorph, Sendolor)?

- Morphine is a centrally acting opioid analgesic. It binds to opiate receptors in the CNS and blocks ascending pain pathways. Reduces patient’s perception of pain without altering cause of the pain. It also causes respiratory depression, peripheral vasodilation, inhibition of intestinal peristalsis, sphincter of Oddi spasm, stimulation of chemoreceptors that cause vomiting and increased bladder tone.

- It is available as both immediate and sustained-release tablets. And also available as oral solution and injection.

- Morphine injection and immediate-release tablets are used in the treatment of severe pain.
And the sustained-release tablets are used to treat severe and persistent pain, especially cancer pain.

- The usual dose of Morphine

ADULTS: PO 10 to 30 mg q 4 hr prn.
Sustained-release tablets: Adults: 30–100 mg q8–12h.
SC/IM 5 to 20 mg/70 kg q 4 hr prn.
IV 2.5 to 15 mg/70 kg in 4 to 5 ml Water for Injection over 5 min prn.
CHILDREN: SC/IM 0.1 to 0.2 mg/kg q 4 hr. Maximum dose: 15 mg.

- Learn more about Morphine (Maracex, Oramorph, Sendolor) mechanism of action, uses, dosage, side effects, and precautions in this video...

- MORE "DRUG IN BRIEF" VIDEOS HERE:
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In this episode, I discuss a medication known as morphine (Kadian, Roxanol).

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Morphine Side Effects and Mechanism of Action | Opioid Analgesics

In this video, you'll learn the side effects of morphine and morphine's mechanism of action. This is a super simple way to learn pharmacology faster and easier in nursing school.
 
So don't worry friend, you don't need to figure everything out alone anymore for nursing school. We're here to help you every step of the way.

The mechanism of action of morphine is that it binds to opioid receptors in the central nervous system, causing the central nervous system to become depressed. That CNS depression leads to less sensation and neurotransmitters, transmitting pain to the body and a decreased perception of pain. Morphine also releases histamine throughout the body.

Morphine's therapeutic effect is pain relief and it also causes blood vessels to dilate (also known as vasodilation) because of the CNS depression and general relaxation that occurs from it.

Knowing this mechanism of action, let's walk through the side effects of morphine in this video!

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TIMESTAMPS:
0:00 Intro
0:51 Trade Names, Generic Names, Classes, and Indications
1:15 Mechanism of Action and Therapeutic Effect
1:51 Side Effects
3:06 Nursing Assessment
4:19 Contraindications
6:05 Patient Education and Nursing Considerations
7:14 MEDICATION DATABASE


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My #1 Pharmacology Hack for Nursing School: https://youtu.be/2yxB36yzYPU

How To Study Pharmacology: https://youtu.be/qmhg0Ev8mNw

Furosemide Mechanism of Action (Nursing Pharmacology): https://youtu.be/P7aDU1PFxPI

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