Confused about how to take Zetia properly? You're not alone! In this complete guide, we break down how to use Zetia (ezetimibe) — a popular cholesterol-lowering medication — in a clear and easy-to-follow way.

🔍 Inside this video, you’ll discover:

🔹 What Zetia (ezetimibe) is and how it works
🔹 The right dosage and how to take it safely
🔹 Whether you should take it with or without food
🔹 Common side effects and how to manage them
🔹 Tips on combining Zetia with statins or lifestyle changes
🔹 What to avoid while on Zetia

💊 Whether you’re new to Zetia or looking to better understand your prescription, this video is your go-to resource for safe, effective, and informed use.

📌 Be sure to like, comment with your questions, and subscribe to He-info for more science-based health videos made simple.

#Zetia #Ezetimibe #CholesterolTreatment #HowToUseZetia #HeartHealth #HeInfo #MedicationGuide #LowerCholesterol #PharmacyTips #StatinAlternatives

Does Zetia ezetimibe cause memory loss Memory loss is not a side effect of Zetia ezetimibe when it is used alone to treat high cholesterol Zetia is often used with other cholesterol lowering medications like statins which have been linked with cognitive impairment memory loss forgetfulness or confusionEzetimibe the active ingredient in Zetia is also found in combination products with a statinVytorin ezetimibe and simvastatinRoszet ezetimibe and rosuvastatinOne case report described a patient with memory loss possibly related to simvastatin Zocor use Gradual memory loss developed following months of simvastatin therapyAfter the statin was changed to pravastatin Pravachol the patients memory returned to an intact state within one monthA rechallenge switching the patient back to simvastatin to see if the memory loss would return was not performed This may be done in some cases to confirm a drugrelated side effectMemory loss and confusion has also been reported with rosuvastatin CrestorEzetimibe is also used in combination with the nonstatins bempedoic acid brand name Nexlizet or fenofibrate to treat high cholesterol However these products have not been reported to cause memory loss in their product labelsThere have been other reports of cognitive impairment like forgetfulness amnesia memory impairment and confusion associated with statin use These cognitive issues have been reported for all statinsRelated questions Can Zetia ezetimibe cause liver damage How does Zetia ezetimibe work to lower cholesterol Is Zetia a statin drugmedication Do statins cause longterm memory loss Memory loss with statins does not appear to be a serious side effect and reverses when the statin is discontinued Memory loss can occur within days to years of starting statin therapy but generally reverses within weeks median time after the medicine is stoppedIf you are having trouble with memory forgetfulness confusion or other cognitive symptoms contact your healthcare provider for further adviceThis is not all the information you need to know about Zetia ezetimibe for safe and effective use and does not take the place of your doctors directions Review the full Zetia information and discuss this information and any questions you have with your doctor or other health care provider

They are called HMG CoA Reductase Inhibitors (Hydroxylmethyl glutaryl Co A)
E.g. Atorvastatin
Rosuvastatin
Fluvastatin
Pita vastatin
Simvastatin
Lovastatin
Pravastatin
Statins generally:
Strong LDL lowering effect
Rosuvastatin is more potent than Atorvastatin
Rosuvastatin and Atorvastatin are more potent than the rest
Fluvastatin is least potent
Fluvastatin, Pitavastatin and Pravastatin are less likely to have drug interactions or muscle toxicity compared to the rest statins
High dose of simvastatin can lead to more myopathy and Rhabdomyolysis
Statins and bile acid sequestrant = synergistic effects
Statins + Ezetimibe = fine

CK is very useful to detect serious complications as:
Myalgia = No rise in CK
Myopathy =CK greater than 5 times
Mild Myositis
Painful muscles/ weakness/ cramps
CK greater than 10 times
Rhabdomyolysis = CK greater than 20,000 u/l
Myoglobinuria
Severe muscle pain
More in females
More in elderly
More in hypothyroidism
More in patients on cyclosporin, erythromycin and Gemfibrozil
You will also educate yourself more,if you listen to this presentation.

PCSK9 Inhibitors. What are they? What for? Repatha. Praluent.

Ezetimibe Secrets of the side effects
**Common side effects:**

* Diarrhea
* Joint pain
* Back pain
* Fatigue
* Abdominal pain
* Nausea
* Stuffy nose
* Weakness

**Uncommon side effects:**

* Allergic reactions (e.g., rash, hives, itching)
* Changes in liver function tests
* Confusion
* Chest tightness or pain
* Rapid heartbeat
* Unusual bleeding or bruising
* Blurred vision
* Dizziness

**Rare side effects:**

* Liver failure
* Jaundice (yellowing of the skin or eyes)
* Severe muscle pain or weakness
* Dark urine
* Fever
* Seizures
* Neuroleptic malignant syndrome (severe adverse reaction to neuroleptic medications)

**Serious side effects that require immediate medical attention:**

* Seizures
* Liver failure
* Severe allergic reaction (anaphylaxis)
* Muscle breakdown (rhabdomyolysis)

Clinical Cousins cover Ezetimibe (Zetia) in their effective and concise "Minute to Master" series.

Zocor now available as the generic simvastatin remains among the top 5 prescription drugs more than 25 years after its approval by the FDA. This moderate potency cholesterol reducing statin may lower the LDL or “bad” cholesterol by 20-40% depending on the dose. While many believe it replaces the need for lifestyle change, weight loss and exercise, benefits of statin therapy remain anchored to these modifications.

While cardiovascular disease accounts for approximately half of all deaths in America, the underlying process remains multifactorial and not merely the result of excessive concentrations of LDL. Advocates of LDL reduction point to its supposed effect on reducing heart attacks. But the ultimate outcome depends more on blood pressure control, diabetes, cigarettes, alcohol, salt, exercise and ultimately genetics. As an added benefit these heart healthy activities also reduce the likelihood of cancer.

Simvastatin must be converted in the body to its active form. It then travels to the liver where it inhibits an enzyme necessary for the manufacture of cholesterol. All of the statins work in a similar manner. Other postulated actions have not been confirmed.

According to the package insert Zocor provides the greatest benefit when taken before bed. It seems the liver synthesizes most of its cholesterol during periods of minimal dietary intake. With stronger statins, these precautions seem unnecessary.

Among the possible side effects are muscle soreness, weakness and tenderness. These occur with unknown frequency but are sufficiently common to warrant a warning. A genetic variant also increases the likelihood of myopathy. In some the blood sugar may be slightly elevated with a proportionate rise in glycosylated hemoglobin or HbA1c.

More than 1 in 3 adults currently receive prescriptions for lipid lowering drugs.

In November, 2018 the American Heart Association updated its recommendations regarding optimal cholesterol levels. Focusing on LDL they seek aggressive lowering far beyond the guidelines established in 2013. Except for the American Association of Clinical Endocrinologists, the AHA maintains the strictest recommendations for reducing LDL. Multiple other professional medical and cardiovascular organizations take a more nuanced view of the subject. Too bad the focus of interest misses the real culprits in heart disease and stroke: poor diet and inadequate exercise.

zetia side effects 💊 - what is zetia used for

So, what is Zetia and how does it work? Zetia, also known as Ezetimibe, is used with a low cholesterol/low-fat diet and exercise to help lower cholesterol in the blood. It may be used alone or with other drugs, such as "statins" or fibrates. Zetia works by reducing the amount of cholesterol your body absorbs from your diet, which in turn may help prevent strokes and heart attacks.

When it comes to taking Zetia, the recommended daily dosage is usually once a day. It can be taken with or without food, but it's important to take it consistently at the same time each day to get the most benefit. It's best to follow your doctor's instructions on when to take Zetia and to not miss any doses.

It's important to note that Zetia is not a substitute for a healthy lifestyle, including a low cholesterol/low-fat diet and regular exercise. It should be used in combination with these lifestyle changes to get the best results in lowering cholesterol levels. As always, talk to your doctor about the best approach for managing your cholesterol and whether Zetia is right for you.
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A new study by cardiologists at The University of Kansas Hospital shows that the heavily advertised cholesterol drug ezetimibe (brand name Zetia; in combination with simvastatin: Vytorin) doesn't provide all of the benefits suggested in the ads. The study appears in The Journal of Clinical Medical Research.

Ezetimibe is known to lower LDL cholesterol in many patients, but does not have well-defined benefits such as reducing the risk of heart attack, stroke or total mortality. Higher LDL levels are associated with greater risk for a heart attack. But the study involving 3,827 patients showed while ezetimibe did lower LDL cholesterol by 12 percent, it had no measurable effect on total mortality.

The prescription drug Zetia is under attack after a study found the drug to be ineffective. Dr. Jennifer Ashton

Welcome to our latest video where we delve into the world of cholesterol management and explore two popular medications: Zetia and Crestor. If you're on a journey to maintain optimal heart health, understanding the differences and benefits of these two drugs is crucial.

In this video, we'll cover: 👉 What is Zetia and how does it work? 👉 What is Crestor and how does it function differently? 👉 Side effects and considerations for both medications 👉 Which medication might be right for you?

Maintaining your heart health is vital, and managing your cholesterol levels plays a significant role in this. Zetia and Crestor are both effective in their own ways, but it's essential to know which one suits your specific health needs best.

Key Takeaways:

Zetia primarily works by reducing the absorption of cholesterol in the intestines.
Crestor, a statin, works by inhibiting the production of cholesterol in the liver.
Both medications have their own sets of benefits and potential side effects that should be discussed with your healthcare provider.
Don't forget to like this video if you found it informative and subscribe to our channel for more health-related content. Your heart health matters, and we're here to provide you with the information you need to make informed decisions.

🩺 Remember: Always consult with your doctor or a healthcare professional before starting any new medication.

Thank you for watching, and here's to a healthier heart! 💓

#HeartHealth #CholesterolManagement #ZetiaVsCrestor #HealthyLiving #HeartCare
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately."

The prescription drug Zetia is under attack after a study found the drug to be ineffective. Dr. Jennifer Ashton

Zetia, also known by its generic name ezetimibe, is a medication commonly prescribed to lower LDL cholesterol levels. It works by reducing the absorption of cholesterol in the small intestine, which in turn lowers the amount of cholesterol circulating in the bloodstream.
What is Zetia?.
Zetia is a medication used to lower LDL (low-density lipoprotein) cholesterol levels in the blood. It is also known by its generic name, ezetimibe. Zetia is often prescribed in combination with other cholesterol-lowering medications, such as statins.
Zetia works by reducing the absorption of cholesterol in the small intestine. It blocks the action of a protein called NPC1L1, which is responsible for the absorption of cholesterol from food. By reducing the amount of cholesterol absorbed from the diet, Zetia can help lower the levels of LDL cholesterol in the bloodstream.
How does Zetia work?.
Zetia works by reducing the amount of cholesterol absorbed in the small intestine. It blocks the action of a protein called NPC1L1, which is responsible for the absorption of cholesterol from food. By reducing the amount of cholesterol absorbed from the diet, Zetia can help lower the levels of LDL cholesterol in the bloodstream.
Zetia is often prescribed in combination with other cholesterol-lowering medications, such as statins, to further lower LDL cholesterol levels. Statins work by blocking the production of cholesterol in the liver, while Zetia blocks the absorption of cholesterol in the small intestine.
Benefits of taking Zetia.
The main benefit of taking Zetia is its ability to lower LDL cholesterol levels. By reducing the absorption of cholesterol in the small intestine, Zetia can potentially minimize the risk of heart disease and other cardiovascular complications.
A study published in the New England Journal of Medicine found that adding Zetia to statin therapy reduced the risk of major cardiovascular events, such as heart attack, stroke, and death from cardiovascular causes, by 6.4% compared to statin therapy alone.
Another study published in the Journal of the American Medical Association found that Zetia, when added to statin therapy, reduced the progression of atherosclerosis, a condition characterized by the buildup of plaque in the arteries, by 58% compared to statin therapy alone.
Side effects of Zetia.
Like any medication, Zetia does come with potential side effects. The most common side effects of Zetia include:.
Diarrhea.
Joint pain.
Fatigue.
Abdominal pain.
Muscle pain.
In rare cases, Zetia can cause liver problems. Symptoms of liver problems include yellowing of the skin or eyes, dark urine, and upper abdominal pain.
If you experience any of these symptoms while taking Zetia, you should contact your healthcare provider immediately. They may need to adjust your dosage or switch you to a different medication.
Who should take Zetia?.
Zetia is typically prescribed to individuals with high LDL cholesterol levels who are unable to lower their cholesterol through diet and lifestyle changes alone. Zetia may also be prescribed to individuals who have a family history of high cholesterol or heart disease.
However, Zetia is not suitable for everyone. Individuals with a history of liver disease or unexplained liver enzyme elevations should not take Zetia. Zetia should also not be used during pregnancy or breastfeeding.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



"

Last year about 30 million prescriptions were issued for cholesterol-lowering drugs Vytorin and Zetia. But a new study questions whether they prevent heart disease. Dr. Jon LaPook reports.

If you're at high risk for a heart attack or stroke, a major new study looks at an alternative treatment using the drug Zetia. Combined with statins, Zetia could reduce the risk of heart problems by 6 percent. Cardiologist Dr. Tara Narula joins "CBS This Morning" to discuss the findings.

Zetia now available as the generic ezetimibe first became available in 2002 as a cholesterol lowering drug. With its quite unique mechanism of action, Zetia reduces absorption of cholesterol from the small intestine. The more popular statin family including Zocor, Lipitor, Pravachol and Crestor works within the liver cell to halt cholesterol production.

Given its distinct activity, combinations of Zetia with a statin remain popular. As an example Vytorin combines Zetia with Zocor also known as simvastatin.

A large trial was conducted years after the drug received marketing approval. Surprisingly it demonstrated Zetia failed to provide any additional benefits when compared against simvastatin alone. It did not decrease the incidence of heart attacks or stroke and may have been associated with increased formation of cholesterol laden arterial plaque.

Even under intense pressure from the medical community, the drug company delayed publication of this information from their own sponsored study as long as possible. After release they feared their $4 billion franchise would tumble. Indeed it did. Especially when other studies confirmed the lack of benefit of Zetia in protecting against heart disease, stroke and cancer.

In 2015 another study was published. It also was funded by the company and is referred to as IMRROVE-IT. Involving 18,000 participants in 39 countries and 1147 different sites they once again tested Zetia alone or in combination with simvastatin among people within 10 days of a cardiac event.

Although heart disease remains the major cause of death in the United States, sponsors of the study conducted it not only here but also in Turkey, Ukraine, Slovakia, Malaysia, India, Ecuador, Colombia, Brazil, Estonia and Hungary among others. Such diverse patient locations create major problems for standardization and oversight.

While the headline claims of a 24% reduction in LDL and a 35% relative reduction in combined cardiovascular events sounds impressive, let’s dig deeper. The outcomes revealed the absolute reduction in events was only 2% after 7 years and the benefits were delayed until after the first year.

Additionally there was not statistically significant improvement in all cause mortality, cardiovascular related death, death from coronary heart disease, fatal heart attack, hemorrhagic stroke, hospitalization for unstable chest pain or need for revascularization.

And by the way the drug did not seem to provide benefits to men, those less than age 75, non-caucasians, diabetics, current smokers or those with normal blood pressure.

If you seem a little skeptical about Zetia, join the crowd.

Last year about 30 million prescriptions were issued for cholesterol-lowering drugs Vytorin and Zetia. But a new study questions whether they prevent heart disease. Dr. Jon LaPook reports.