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6.14. An Antiviral Arms-Race: Acyclovir, Oseltamivir & More
6.14. An Antiviral Arms-Race: Acyclovir, Oseltamivir & More Side Effects 1 Views • 13 days ago

The timely choice of the right antiviral isn't just a treatment decision—it's a critical turning point for patient outcomes. In this clinical review, we provide a clear and concise guide to mastering the use of essential antiviral agents in your practice.

We cover the core principles of antiviral stewardship, emphasizing when to treat and, just as importantly, when to stop. Explore the key indications for our most common antiviral families, including Acyclovir/Valacyclovir for HSV and VZV, Oseltamivir for influenza, and Ganciclovir for CMV in immunocompromised patients.

Through practical clinical scenarios, we'll compare dosing strategies for conditions like shingles versus life-threatening HSV encephalitis. We also navigate the most important side effects to monitor, such as Acyclovir-induced neurotoxicity and renal toxicity, and discuss crucial considerations for special populations, including pregnancy. Finally, we'll break down the clinical pathway for managing antiviral resistance when first-line therapies like Acyclovir fail.

🕒 Timestamps:
00:00 - Intro: A Turning Point for Patient Outcomes
00:49 - Chapter 1: Principles of Use (Judicious Prescribing)
01:35 - Chapter 2: Key Indications (Agent to Pathogen)
02:12 - Chapter 3: Dosing & Clinical Cases
03:15 - Chapter 4: Side Effects & Complications
04:09 - Chapter 5: Special Populations (Pregnancy & High-Risk)
05:12 - Chapter 6: Resistance & Clinical Challenges

Sources:
This video was made with Gemini's deep research capabilities and NotebookLM.

Disclaimer: This video is for educational and informational purposes only and is not intended as medical advice. The content is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Tags & Hashtags:
#Antiviral #Pharmacology #Acyclovir #Valacyclovir #Oseltamivir #Tamiflu #Influenza #Herpes #Shingles #InfectiousDisease #Virology #MedicalEducation #ClinicalPharmacy #MedStudent #AntiviralResistance

Acyclovir cream / Acivir cream uses, side effects LEARN ABOUT MEDICINE
Acyclovir cream / Acivir cream uses, side effects LEARN ABOUT MEDICINE Side Effects 1 Views • 13 days ago

Watch this video in English language: - https://youtu.be/A-RZLwOcNLk

Acyclovir cream / Aciclovir cream is an antiviral cream used in the treatment of herpes virus infection like herpes zoster, genetial herpes, cold sores, blister on lip, chickenpox etc..
Acyclovir cream brand names are
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Acyclovir cream is available in 5 % w/w strength and packing are 5 gm, 10 gm, 15 gm etc..
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ACYCLOVIR, What is acyclovir used for, Acyclovir (ZOVIRAX, SITAVIG) review
ACYCLOVIR, What is acyclovir used for, Acyclovir (ZOVIRAX, SITAVIG) review Side Effects 0 Views • 13 days ago

Acyclovir review, aciclovir: What is acyclovir, what is acyclovir used for, acyclovir uses, acyclovir dosage, acyclovir side effects,acyclovir moa, acyclovir brand names: Sitavig, Zovirax Capsules, Zovirax tablets.

What is acyclovir? and What is acyclovir used for?

Acyclovir is used to decrease pain and speed the healing of sores or blisters in people who have varicella (chickenpox), herpes zoster (shingles; a rash that can occur in people who have had chickenpox in the past), and first-time or repeat outbreaks of genital herpes (a herpes virus infection that causes sores to form around the genitals and rectum from time to time).
Acyclovir is also sometimes used to prevent outbreaks of genital herpes in people who are infected with the virus.
Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body.
Acyclovir will not cure genital herpes and may not stop the spread of genital herpes to other people.


How to use acyclovir?

Acyclovir comes as a tablet, a capsule, and a suspension (liquid) to take by mouth. It also comes as a delayed-release buccal tablet to apply to the upper gum of the mouth.
The tablets, capsules, and suspension are usually taken with or without food two to five times a day for 5 to 10 days, starting as soon as possible after your symptoms begin.
When acyclovir is used to prevent outbreaks of genital herpes, it is usually taken two to five times a day for up to 12 months.
The delayed-release buccal tablet is usually applied with a dry finger as a one-time dose within 1 hour after itching, redness, burning or tingling cold sore symptoms begin but before the cold sore appears.
Take or use acyclovir at around the same time(s) every day.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take or use acyclovir exactly as directed.
Do not take or use more or less of it or take it more often or for a longer time than prescribed by your doctor.

Do not chew, crush, suck, or swallow the delayed-release buccal tablets. Drink plenty of liquids, if you have a dry mouth while using the delayed-release buccal tablets.

To use buccal acyclovir, follow these steps:

Find the area on the upper gum above your left and right incisor teeth (the teeth just to the left and right of your two front teeth).

With dry hands, remove one delayed-release tablet from the container.

Gently apply the tablet to the upper gum area as high as it will go on your gum above one of your incisor teeth on the side of your mouth with the cold sore. Do not apply it to the inside of the lip or cheek.

Hold the tablet in place for 30 seconds.

If the tablet does not stick to your gum or if it sticks to your cheek or the inside of your lip, reposition it to stick to your gum.
Leave the tablet in place until it dissolves.

Do not interfere with the placement of the tablet.
Check to see if the tablet is still in place after eating, drinking, or rinsing your mouth.

If the delayed-release buccal tablet comes off within the first 6 hours of application, reapply the same tablet.
If it still will not stick, then apply a new tablet. If you accidentally swallow the tablet within the first 6 hours of application, drink a glass of water and place a new tablet on your gum. If the tablet falls off or is swallowed 6 or more hours after application, do not apply a new tablet until your next regular time.

Avoid the following while you are using acyclovir buccal delayed-release tablet:

Do not chew gum, touch, or press the buccal tablet after it has been applied.
Do not wear upper dentures.
Do not brush your teeth until it dissolves. If your teeth need to be cleaned while the tablet is in place, rinse the mouth gently.

Shake the suspension well before each use to mix the medication evenly.

Your symptoms should improve during your treatment with acyclovir.
Call your doctor if your symptoms do not improve or if they get worse.

Take or use acyclovir until you finish the prescription, even if you feel better. If you stop taking acyclovir too soon or skip doses, your infection may not be completely treated or may become more difficult to treat.
The delayed-release buccal tablet is applied as a one-time dose.


Acyclovir may cause side effects.
Tell your doctor if any of these symptoms are severe or do not go away:

upset stomach.
vomiting.
diarrhea.
dizziness.
tiredness.
agitation.

Anti-Herpetic Drugs - Side Effects and Resistance
Anti-Herpetic Drugs - Side Effects and Resistance Side Effects 1 Views • 13 days ago

Side effects of anti-herpetic drugs (acyclovir, ganciclovir, etc) include renal toxicity, neutropenia, anemia, and thrombocytopenia. If resistance develops, foscarnet or cidofovir can be used but they are more toxic. For more videos and questions, visit - https://www.macrophage.co. Subscribe - https://goo.gl/EMRlRa. Support us on Patreon - https://goo.gl/bhmrgJ.

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Aciclovir Side Effects
Aciclovir Side Effects Side Effects 0 Views • 13 days ago

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Zovirax -  - Generic Name , Brand Names, How to use, Precautions, Side Effects
Zovirax - - Generic Name , Brand Names, How to use, Precautions, Side Effects Side Effects 1 Views • 13 days ago

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Generic Name, Brand Names, What is ?,
Vital information, Dosage info,
Before taking this medicine (Precautions ), How to use ,
Miss a dose, Overdose , Stop or Avoid Taking ,
Side Effects, Other Drugs Will Affect,
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Aciclovir - Pharmacology, Indication, Dosage and Uses, Contraindication and Precaution
Aciclovir - Pharmacology, Indication, Dosage and Uses, Contraindication and Precaution Side Effects 0 Views • 13 days ago

Aciclovir - Pharmacology, Indication, Dosage and Uses, Contraindication and Precaution.

Aciclovir.
Aciclovir (also known as acyclovir) is indeed an antiviral medication commonly used for the treatment of various viral infections. Its primary applications include the treatment of herpes simplex virus infections, chickenpox (varicella-zoster virus), and shingles (herpes zoster). This medication works by inhibiting the replication of the viruses, thereby helping to reduce the severity and duration of these infections.

Pharmacology:
• Aciclovir is a synthetic purine derivative, targeting Herpes simplex virus (HSV) and Varicella zoster virus by hindering DNA synthesis, thus inhibiting viral replication. Its antiviral action relies on intracellular conversion to Aciclovir Triphosphate, primarily facilitated by the virus-coded thymidine kinase. This conversion chain leads to the formation of the pharmacologically active triphosphate form. Percutaneous absorption of Aciclovir is minimal when topically applied to intact skin.

Indications:
• Aciclovir Cream is indicated for treating initial and recurrent labial and genital Herpes simplex infections, with early initiation recommended.
• Acyclovir tablets are indicated for viral infections involving herpes simplex virus (type I & II) and varicella-zoster virus, encompassing herpes zoster, chickenpox, and herpes simplex infections on the skin and mucous membranes, including both initial and recurrent genital herpes. It's also prescribed for prophylaxis in immunocompromised patients.

Dosage and Administration:
• Aciclovir Cream should be applied to affected lesions five times daily for 5-10 days, ensuring cleanliness and dryness. Patients are advised to wear loose-fitting clothing to prevent irritation.
• Acyclovir dosages vary, with oral administration for herpes simplex initial therapy (200mg, 5 times daily for 10 days), herpes simplex chronic suppressive therapy (200-400mg, 2-4 times daily for 12 months), herpes zoster (800mg, 5 times at 4-hour intervals for 7-10 days), and varicella-zoster (20mg/kg, not exceeding 800mg, 4 times daily for 5 days). Dosing is adjusted for children under 2 years and the elderly as required, or as directed by a physician.

Use in Pregnancy and Lactation:
• Both medications have specific considerations during pregnancy and lactation. Aciclovir is pregnancy category B, with caution exercised when used by nursing mothers. Acyclovir should be used during pregnancy when the potential benefit justifies potential fetal risk, and nursing mothers should use it with caution.

Contraindications:
• Aciclovir is contraindicated in patients hypersensitive to the drug, while Acyclovir should be avoided by those who develop hypersensitivity or intolerance to its components.


Precautions:
• Caution is needed when administering Acyclovir to patients with renal impairment, and dosages should be adjusted based on creatinine clearance.

Side Effects:
• Side effects for both medications may include fever, headache, pain, edema, anaphylaxis (rarely), dizziness, somnolence, gastrointestinal symptoms, and more.
• Transient burning or stinging may occur with Aciclovir Cream, and mild skin reactions such as erythema and flaking have been reported.

Storage:
• Store both medications below 25°C, protected from light, and out of the reach of children.

Acyclovir Eye Drops, Eye Ointment Side Effects (Ophthalmic Acyclovir)
Acyclovir Eye Drops, Eye Ointment Side Effects (Ophthalmic Acyclovir) Side Effects 1 Views • 13 days ago

What are the side effects of Acyclovir when it is applied to the eyes as eye drops, or as an eye ointment? The effects of taking ophthalmic Acyclovir are quite minimal, and this video will go through each one, and its incidence in the population.

Also see the side effects of Acyclovir when taken via other routes:

Side Effects of Acyclovir Tablets/Capsules/Suspension (Oral) -
https://www.youtube.com/watch?v=yfMfnyqmPBA
Side Effects of Acyclovir Cream – https://www.youtube.com/watch?v=QjpV4makh98
Side Effects of Acyclovir Injections (Intravenous) - https://www.youtube.com/watch?v=DuH2pCnvlF0

Introduction - 0:11
Common side effects - 0:26 (Over 1% of the population)
Uncommon side effects - 0:36
Final notes: 0:51

Read the full transcript: http://www.pharmacytrust.com/a....cyclovir-opthalmic-s

Website: http://www.pharmacytrust.com
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MEDICAL DISCLAIMER:
This video is a medical not intended to replace professional medical advice. Please contact your healthcare provider with any questions regarding your medicine or condition. Do not disregard professional medical advice or delay seeking it based on information from this content. Relying on information provided in this content is done at your own risk.

Turmeric Health Benefits: https://www.youtube.com/watch?v=JFNXJnpG3Ec

Zovirax (Aciclovir) Tablets/Liquid/Cream
Zovirax (Aciclovir) Tablets/Liquid/Cream Side Effects 1 Views • 13 days ago

Zovirax is used to treat viral infections such as genital herpes (a sexually transmitted infection), cold sores, shingles (sometimes called herpes zoster), and chickenpox. Shingles and chickenpox are caused by the varicella-zoster virus.

If you would like to find out more visit: 
http://www.lynchspharmacy.com/....medicine/zovirax-tab
http://www.lynchspharmacy.com

You can also visit Lynch's Pharmacy in Broadale, Maryborough Hill, Cork.

Please note that this video is meant for educational purposes only, and should not be used as a means to diagnose any health condition. You should always consult your doctor if you have any concerns regarding your health or medication.We are not selling or advertising any product our videos include.

Thank you for watching!

56# Acyclover Zovirax   Uses, Dose, Side effects, Precautions, Indications
56# Acyclover Zovirax Uses, Dose, Side effects, Precautions, Indications Side Effects 1 Views • 13 days ago

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