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Do Benzodiazepines Cause Dementia? Side Effects 1 Views • 5 months ago

Benzodiazepines are a type of medication prescribed to people with anxiety and panic disorders. But do they cause dementia? In this video, I talk about the research on benzodiazepines and dementia, and what it means for people taking these medications.

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REFERENCES:
Allison, C, and J A Pratt. “Neuroadaptive processes in GABAergic and glutamatergic systems in benzodiazepine dependence.” Pharmacology & therapeutics vol. 98,2 (2003): 171-95. doi:10.1016/s0163-7258(03)00029-9

Shi, Y., Cui, M., Ochs, K. et al. Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO). Nat Neurosci 25, 317–329 (2022). https://doi.org/10.1038/s41593-022-01013-9

Lauren B Gerlach, DO, MS, Hyungjin Myra Kim, ScD, Rosalinda V Ignacio, MS, Julie Strominger, MS, Donovan T Maust, MD, MS, Use of Benzodiazepines and Risk of Incident Dementia: A Retrospective Cohort Study, The Journals of Gerontology: Series A, Volume 77, Issue 5, May 2022, Pages 1035–1041, https://doi.org/10.1093/gerona/glab241

Joyce, G, Ferido, P, Thunell, J, Tysinger, B, Zissimopoulos, J Benzodiazepine use and the risk of dementia. Alzheimer's Dement. 2022; 8:e12309. https://doi.org/10.1002/trc2.12309

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Anxiety Medications - Pharmacology - Nervous System | @LevelUpRN Side Effects 1 Views • 5 months ago

Cathy covers medications that are used to treat anxiety, including: benzodiazepines and buspirone.

Our Pharmacology video tutorial series is taught by Cathy Parkes BSN, RN, CWCN, PHN and intended to help RN and PN nursing students study for their nursing school exams, including the ATI, HESI and NCLEX.

#NCLEX #pharmacology #nervous #HESI #Kaplan #ATI #NursingSchool #NursingStudent⁠ #Nurse #RN #PN #Education #LVN #LPN #anxiety

0:00 What to Expect
0:19 Benzodiazepines
1:07 Mode of Action & Side Effects
1:28 Administration
1:42 Antidote
2:17 Buspirone
2:31 Mode of Action
2:41 Side Effects
2:55 Administration
3:17 Patient Teaching
3:54 What’s Next

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9 Side Effects Of Diazepam (Doctors Never Say) | Diazepam Side Effects Side Effects 1 Views • 5 months ago

🚨 DIAZEPAM DANGERS: 9 Research-Proven Side Effects You MUST Know 🚨

Are you taking diazepam (Valium) or considering it? STOP and watch this first! Discover the 9 scientifically-proven side effects that doctors rarely discuss. This isn't opinion—it's hard research from top medical journals.

🔍 What You'll Learn: ✅ Cognitive impairment that may be PERMANENT ✅ Dangerous respiratory depression (FDA BLACK BOX WARNING) ✅ Addiction potential higher than you think ✅ Why elderly patients face DOUBLE fall risk ✅ Paradoxical reactions that cause OPPOSITE effects ✅ Withdrawal symptoms worse than heroin (research-backed) ✅ Memory problems that persist after stopping ✅ Depression risk increases with long-term use ✅ Muscle weakness and coordination problems

📚 RESEARCH REFERENCES:

British Journal of Clinical Pharmacology (2007) - Diazepam cognitive alertness impairment https://bpspubs.onlinelibrary.....wiley.com/journal/13
Current Medical Research and Opinion (2006) - Memory and attention deficits https://www.tandfonline.com/journal/icmo20
WHO Expert Committee Report (2003) - Benzodiazepine dependence guidelines https://www.who.int/publications
Journal of Clinical Psychopharmacology (1992) - Muscle relaxant properties and weakness https://journals.lww.com/psychopharmacology
FDA Black Box Warning (2016) - Respiratory depression and combination risks https://www.fda.gov/drugs/drug....-safety-and-availabi
Psychopharmacology Bulletin (1991) - Paradoxical reactions in vulnerable populations https://psychopharmacologybulletin.org
International Journal of Clinical Pharmacology and Therapeutics (2004) - GI effects https://www.dustri.com/journal....s/clinical-pharmacol
BMJ Open (2017) - Depression correlation with benzodiazepine use https://bmjopen.bmj.com
JAMA (2005) - Falls and fractures in elderly benzodiazepine users https://jamanetwork.com/journals/jama
🔬 ADDITIONAL RESEARCH SOURCES:

Archives of Clinical Neuropsychology - Long-term cognitive effects
Translational Psychiatry - Memory impairment studies
European Addiction Research - Cognitive dysfunction profiles
Frontiers in Pharmacology - Real-world adverse events
StatPearls (NCBI) - Comprehensive diazepam clinical data
📝 MEDICAL DISCLAIMER: This content is for educational purposes only and is not medical advice. Always consult your healthcare provider before making any changes to your medications. Never stop benzodiazepines abruptly as this can cause life-threatening seizures.

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#DiazepamSideEffects #ValiumDangers #BenzodiazepineWithdrawal #MedicalResearch #HealthWarning #PharmaceuticalTruth #MedicationSafety #ElderlyMedication #AnxietyMedication #DrugDependence #CognitiveDamage #MedicalAwareness #PatientSafety #HealthEducation #MedicationRisks

Related Videos You Should Watch: 🎥 "Benzodiazepine Withdrawal: The Hidden Crisis" 🎥 "Anxiety Medications: Natural Alternatives That Actually Work" 🎥 "Elderly Medication Dangers: What Families Need to Know"
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The content shared on this YouTube channel regarding health tips and home remedies serves purely for informational purposes and is not a substitute for professional medical guidance. Before trying any remedies or treatments featured here, viewers should seek advice from a licensed medical professional. The channel owner and creators will not be liable for any outcomes resulting from the application or misapplication of the information provided. Viewer discretion is recommended.

Valium Effects | What You Need To Know About Diazepam Side Effects 3 Views • 5 months ago

Valium! How does it work? & what are the side effects? In this video I will look at the science behind Valium to determine whether or not it is the right drug for you.

Valium Cheat Sheet: E-mail “[email protected]" and I will send it straight to you

What is Valium?
Valium, also known as Diazepam, is a benzodiazepine drug that produces a calming effect. It is used to treat anxiety, seizures and even insomnia.

How Does Valium Work?
Valium works by binding to GABA ion channels and promoting GABA activity in your nervous system.
GABA is an inhibitory neurotransmitter, so by increasing GABA activity, valium effectively inhibits the nervous system, reducing excitement signals and calming your brain and your body.

What are the side effects?
Valium can cause dizziness, drowsiness, weakness and confusion.

Don’t take valium with alcohol, it will amplify the effects which can lead to respiratory depression and loss of consciousness.

Also, be careful with grapefruit! It is metabolised by an enzyme called CYP3A4, and so is valium. When combined, it can slow your metabolism so you absorb more of the drug, making it far more potent!

Finally, if you use valium regularly, you will build up a tolerance, meaning you will need more of the drug to get the same calming effects, but this can be very dangerous and potentially lead to an overdose.
If you find yourself taking Valium regularly, try to get some help and find an alternative relaxant.

References and citations for this video can be found below
How valium works: https://link.springer.com/arti....cle/10.2165/00003088

Valium vs similar drugs: https://psycnet.apa.org/record/1983-26283-001

Valium treatment of anxiety: https://jamanetwork.com/journa....ls/jamapsychiatry/ar

Grapefruit and valium: https://www.fda.gov/consumers/....consumer-updates/gra

Valium and addiction: https://www.aafp.org/afp/2000/....0401/p2121.html?wvse

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00:00 Valium Intro
00:31 What is Valium
01:17 Valium Side Effects
01:53 Valium and Alcohol
02:04 Valium and Grapefruit
02:37 Valium Addiction and Tolerance
02:55 Taking Valium

Benzodiazepines Side Effects (& Important Consequences of Long-Term Use) | Diazepam, Lorazepam Side Effects 2 Views • 5 months ago

Benzodiazepines Side Effects (& Very Important Consequences of Long-Term Use)

Benzodiazepines are a class of medication, often used to treat short-term anxiety conditions, including panic attacks and specific phobias. Some examples of Benzodiazepines include diazepam, lorazepam, and alprazolam. Benzodiazepines lead to generalized decreased neuronal activity, leading to characteristic signs and symptoms, which we discuss in this lesson.

I hope you find this lesson helpful. If you do, please like and subscribe for more lessons like this one!

JJ

REFERENCES:
https://reference.medscape.com..../drug/valium-valtoco
https://www.ncbi.nlm.nih.gov/books/NBK470159/
https://pubmed.ncbi.nlm.nih.go....v/2899980/#:~:text=C
https://pubmed.ncbi.nlm.nih.gov/20305598/

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How Does Clotrimazole Compare To Fluconazole? - The Health Brief Side Effects 4 Views • 5 months ago

How Does Clotrimazole Compare To Fluconazole? In this informative video, we will discuss the differences between Clotrimazole and Fluconazole, two commonly used antifungal medications. Both of these drugs play a significant role in treating fungal infections, but they come with unique characteristics that make them suitable for different scenarios. We will cover how each medication works, their forms of administration, and their effectiveness against conditions like vulvovaginal candidiasis and oral thrush.

Additionally, we will explore the side effects associated with both Clotrimazole and Fluconazole, as well as their convenience in terms of application and accessibility. Understanding the nuances of these medications can help you make the right choice for your treatment needs.

Whether you are a patient seeking information or someone interested in the field of general medicine, this video will provide you with essential knowledge about these antifungal agents. Join us as we break down the key points and help you navigate your options. Don't forget to subscribe to our channel for more informative discussions on health topics and treatments.

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#Clotrimazole #Fluconazole #Antifungal #FungalInfections #YeastInfections #VulvovaginalCandidiasis #OralThrush #MedicationComparison #HealthEducation #Pharmacy #PatientCare #TopicalTreatment #OralMedication #SideEffects #HealthTips

About Us: At The Health Brief, we are dedicated to making general medicine accessible and engaging for everyone. Our channel focuses on a wide range of topics, including common health concerns, medical advancements, and wellness tips. We aim to empower viewers with knowledge that can help them make informed decisions about their health and well-being. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Clotrimazole Pharmacology Side Effects 5 Views • 5 months ago

On this podcast episode, I discuss Clotrimazole pharmacology, adverse effects, indications, administration, and much more.

Clotrimazole is an imidazole antifungal that exerts its pharmacological effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This inhibition compromises membrane integrity, leading to leakage of cellular contents and ultimately fungal cell death.

Clotrimazole is primarily used topically due to poor systemic absorption when administered via the skin or mucous membranes, which limits systemic side effects.

When clotrimazole is used intravaginally or orally in lozenge form, localized concentrations are sufficient to treat mucocutaneous infections without significant systemic exposure.

Pay attention when clotrimazole is used frequently to treat Candida infections as corticosteroids, immunosuppression, and antibiotics may increase the risk of this type of infection.

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What Are The Side Effects Of Clotrimazole Topical? - Pharmaceutical Insights Side Effects 3 Views • 5 months ago

What Are The Side Effects Of Clotrimazole Topical? In this informative video, we discuss the side effects associated with Clotrimazole topical, a commonly used antifungal medication for treating various skin infections. Understanding the potential reactions to this treatment is essential for anyone considering its use. We will cover the mild side effects you may encounter, which typically occur at the application site, as well as the more serious reactions that could indicate an allergy. Recognizing these symptoms can help you respond appropriately and seek medical attention when necessary.

We also emphasize the importance of monitoring your skin's response to the medication and consulting with a healthcare provider if you notice any concerning changes. Additionally, we will touch on the significance of seeking medical advice if your fungal infection does not show improvement within a specified time frame. This video aims to equip you with the knowledge needed to use Clotrimazole safely and effectively, ensuring that you are well-informed about what to expect during your treatment.

Join us for this essential discussion, and subscribe to our channel for more informative content on medications and health-related topics.

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#Clotrimazole #TopicalMedication #FungalInfection #SkinCare #AllergicReactions #SkinIrritation #Healthcare #MedicationSafety #Pharmaceuticals #HealthTips #Antifungal #PatientEducation #MedicalAdvice #SkinHealth #DrugSideEffects

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Clotrimazole Uses, Side Effects, Precautions, Interactions Side Effects 3 Views • 5 months ago

Clotrimazole Uses, Side Effects, Precautions, Interactions

Uses
Clotrimazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and other fungal skin infections (candidiasis). This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Clotrimazole is an azole antifungal that works by preventing the growth of fungus.

How to use Clotrimazole
Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply this medication to the affected skin, usually twice a day or as directed by your doctor. Dosage and length of treatment depends on the type of infection being treated. Do not apply this more often than prescribed. Your condition will not clear faster, but side effects may be increased.
Apply enough medication to cover the affected area and some of the surrounding skin. After applying this medication, wash your hands. Do not wrap, cover or bandage the area unless directed to do so by your doctor.
Do not apply this medication in the eyes, nose, mouth, or vagina.
Use this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day.
Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.
Tell your doctor if your condition lasts after 4 weeks of treatment or gets worse at any time.

Side Effects
Burning, stinging, swelling, irritation, redness, pimple-like bumps, tenderness, or flaking of the treated skin may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly.
If your doctor has directed you to use this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: blistering, oozing, open sores.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions
Before using clotrimazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals such as econazole, ketoconazole, or miconazole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Interactions
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

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What Are The Side Effects Of Clotrimazole? - Skin Savvy Dermatology Side Effects 2 Views • 5 months ago

What Are The Side Effects Of Clotrimazole? In this informative video, we will discuss the side effects associated with clotrimazole, a commonly used antifungal medication in dermatology. This treatment is effective for various skin conditions, particularly fungal infections like athlete's foot and jock itch. Understanding the potential side effects is important for anyone considering this medication.

We will outline the common side effects that users may experience, such as skin irritation, redness, and a burning sensation at the application site. Additionally, we will cover less common but more serious side effects that may occur, including blistering and allergic reactions. Knowing what to look for can help you make informed decisions about your treatment.

If you or someone you know is using clotrimazole, this video will provide essential information to ensure a safe and effective experience. We encourage you to consult with a healthcare professional if you notice any unusual symptoms or if side effects persist. Stay informed and proactive about your skin health!

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#Clotrimazole #FungalInfections #Dermatology #SkinHealth #AthletesFoot #JockItch #SkinIrritation #AllergicReactions #MedicationSideEffects #HealthAwareness #Dermatologist #SkinCare #TopicalTreatment #PharmacyAdvice #PatientEducation

About Us: Welcome to Skin Savvy Dermatology, your go-to source for all things skin! Our channel is dedicated to empowering you with the knowledge and tools to achieve healthy, glowing skin. From understanding common skin conditions to exploring the latest treatments and skincare routines, we cover a wide range of topics that cater to all skin types and concerns. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Clotrimazole cream mechanism of action | Clotrimazole antifungal cream for yeast infection Side Effects 4 Views • 5 months ago

Clotrimazole cream mechanism of action | Clotrimazole antifungal cream for yeast infection - This lecture explains Clotrimazole cream mechanism of action | Clotrimazole antifungal cream for yeast infection.
In this video, we'll explore the clotrimazole cream mechanism of action and discuss its use for treating yeast infections.

If you're suffering from a yeast infection and want to find an effective treatment, be sure to watch this video! We'll discuss the clotrimazole cream mechanism of action and how it can help you get rid of your yeast infection quickly and easily. Thanks for watching!
In this video, we'll explore the mechanism of action of clotrimazole cream, a commonly used antifungal cream. We'll discuss the different uses for clotrimazole cream, and how it can help treat fungal infections.

If you're looking for an antifungal cream that you can use to treat yeast infections, then be sure to watch this video! We'll discuss the different uses for clotrimazole cream and how it can help treat fungal infections. By the end of the video, you'll have a better understanding of the clotrimazole cream mechanism of action and how it can help treat fungal infections.
In this video, we'll take a look at the clotrimazole cream mechanism of action. This will help us understand why clotrimazole is a successful antifungal cream for yeast infections.

If you're looking for an antifungal cream that you can trust to treat your yeast infection, then look no further than clotrimazole. This cream has a well-known and successful mechanism of action that will help you get rid of your yeast infection quickly and easily!

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Benzodiazepine Dependence and Withdrawal - How To Avoid This Side Effects 1 Views • 5 months ago

Benzodiazepine or benzos for short, is the class of drug that works at the GABA receptors in your brain to produce a relaxing or sedative effect. We use benzodiazepines to treat short-term anxiety and sleep. Some doctors will use them as a muscle relaxer – Valium is pretty typical for this. They can also be used to stop a seizure. You may get valium or Ativan prior to a procedure like a colonoscopy.

The common benzodiazepines or benzos for short that we use for anxiety are Ativan, Klonopin, Xanax and Valium.

Benzodiazepines are habit forming and it’s easy to become addicted to them. Here’s why. Benzos cause a tolerance effect. This means if you take them regularly like daily or several times a week, overtime the effect can wear off and you;ll need to take more to get the same effect. So now instead of a half pill or one pill working, you notice you need two pills.

This is a medication tolerance effect. It can happen to anyone and is not the same as addiction. If this happens to you, it doesn’t mean you’ve been misusing the medication or have an addition. Addiction involves developing a psychological dependence on it where you need to take it.

Daily, long term use is associated with cognitive changes like not being as mentally sharp. It can create balance problems in some people where you just aren’t quite solid on your feet. This can be a big problem with elderly people by increasing their risk of falls.

In this video I discuss the details of what dependence looks like versus addiction. I also discuss how to avoid developing a dependence.

Want to know more about mental health and self-improvement? On this channel I discuss topics such as bipolar disorder, major depression, anxiety disorders, attention deficit disorder (ADHD), relationships and personal development/self-improvement. I upload weekly. If you don’t want to miss a video, click here to subscribe. https://goo.gl/DFfT33

Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.

How to use Clonazepam? (Klonopin, Rivotril) - Doctor Explains Side Effects 3 Views • 5 months ago

In this video we will cover everything you need to know about Clonazepam, also known as Rivotril. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

Generic name: Clonazepam.
Brand names: Klonopin and Rivotril.
Available as tablet, drops or injection.

How to use it?
Tablet: Swallow the tablets with half a glass of water.
Drops: put the number of drops you need to take on a spoon. Mix them with something to drink and drink it.
Injection: If you want to use it as an injection. Your doctor or nurse will administrate it.

Duration of use?
It is often discouraged to use Clonazepam for more than several weeks straight. As this can increase your risk for becoming dependent on this drug. Which means that you will get withdrawal symptoms when you stop taking it.

When to use it?
Clonazepam is part of a group of drugs called Benzodiazepine. It can be used to decrease symptoms of several medical conditions:
- Epilepsia
- Panic disorder
- social phobia
- And muscle cramps

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms.Therefore always use the precise amount and frequency your doctor prescribed you.

- When treating epilepsy in Adults the initial oral dose is 1-2 mg/day. This can be slowly increased up to a maintenance dose of 2-4 mg/day. The maximum dose would be 20mg/day.

What are common the side-effects?
- Uncommon (affects 10 to 30 in 100 people): Drowsiness and fatigue.
- Rare (affects 1 to 10 people in 100): Slurred speech, difficulty concentrating, slowed thinking, memory problems, impaired coordination, double vision, muscle weakness, balance problems and dizziness.
- Very rare (affects less than 1 in 100 people): Nausea, diarrhoea, headache, incontinence, difficulty breathing, rash, itching, impotence, seizures and bruising.

Safety:
First of all be careful to combine clonazepam with alcohol. As this might increase it’s side effects.
In addition, it can be dangerous to drive while using this drug. As it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects than please do not drive.
Furthermore, clonazepam can have interactions with other drugs your are taking. always discuss this with your prescribing doctor.

Pregnancy and Lactation:
Research shows that use of clonazepam could be dangerous. However, there are some exceptions. Therefore always discuss this with your personal doctor.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

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Literature:
1: Farmacotherapeutisch Kompas. (2021). Clonazepam.
2: Apotheek.nl (2021). Clonazepam.

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