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#1: levothyroxine (Synthroid) | Hypothyroidism and Thyrotropin-Dependent Cancers | Drug Cards Daily

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Drug Cards Daily | Episode #1: levothyroxine (Synthroid, Levoxyl) | Treating Hypothyroidism and Thyrotropin-Dependent Cancers

This episode of Drug Cards Daily is on the drug levothyroxine. Levothyroxine has many brand names such as Synthroid, and Tirosint (to name a few) and is used as first-line in hypothyroidism. It is also used in the treatment of thyrotropin-stimulating hormone (TSH) dependent thyroid cancers. The main dosage form is tablets and it comes in a wide variety of strengths commonly dosed in micrograms (mcg). Dosing is individualized with a general standard of either approximately 1-1.6 mcg/kg/day or 50 mcg/day. From there adjustments are made in 12-25 mcg increments every 3-6 weeks until serum TSH and T4 is at a normal range for greater than 5-6 weeks. It is recommended to be taken in the morning 30-60 minutes before food. If needed it can be crushed but levothyroxine should not be administered within 4 hours of calcium or iron containing products.

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