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Calcitriol | Medicine Information
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• 08/17/25
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Calcitriol | Medicine Information
Calcitriol is the active form of vitamin D in the body. It is a steroid hormone that is produced in the kidneys from vitamin D3, which is obtained from the diet or synthesized in the skin from sunlight exposure. Calcitriol plays an important role in the regulation of calcium and phosphate metabolism, which is essential for bone health.
Calcitriol acts on the cells in the intestine, bones, and kidneys to increase the absorption of calcium and phosphate from the diet, enhance bone mineralization, and reduce urinary excretion of calcium. It also has immunomodulatory and anti-inflammatory effects, and is used in the treatment of certain autoimmune and inflammatory disorders.
Deficiency of calcitriol can lead to a variety of health problems, including rickets, osteomalacia, and osteoporosis. Excessive production of calcitriol can cause hypercalcemia, which can lead to the formation of kidney stones and other complications. Therefore, it is important to maintain proper levels of calcitriol in the body through a balanced diet, adequate sunlight exposure, and appropriate medical treatment when necessary.
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