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Carbamazepine / Tegretol

1 Views • 08/26/25
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Carbamazepine

Tegretol is the brand name for carbamazepine, which is a medication used to treat several conditions, including epilepsy, bipolar disorder, and trigeminal neuralgia. Here are some indications, side effects, and interactions associated with Tegretol (carbamazepine):
Indications:
Epilepsy: Tegretol is used to treat certain types of seizures, including partial seizures and tonic-clonic seizures.
Bipolar disorder: Tegretol is used as a mood stabilizer to prevent and treat manic episodes.
Trigeminal neuralgia: Tegretol is used to treat the facial pain associated with trigeminal neuralgia.
Side effects:
Drowsiness
Dizziness
Nausea and vomiting
Constipation or diarrhea
Headache
Blurred or double vision
Skin rash or itching
Low sodium levels in the blood (hyponatremia)
Serious side effects that require immediate medical attention include:
Signs of an allergic reaction (e.g., hives, difficulty breathing, swelling of the face, lips, tongue, or throat)
Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis)
Blood disorders (e.g., leukopenia, anemia, thrombocytopenia)
Liver problems (e.g., liver failure, hepatitis)
Serious infections (e.g., sepsis, pneumonia)
Suicidal thoughts or behavior
Interactions:Tegretol may interact with other medications, including:
Antidepressants, such as fluoxetine and paroxetine
Antipsychotics, such as clozapine and haloperidol
Blood thinners, such as warfarin
Birth control pills
HIV medications, such as ritonavir and saquinavir
Other seizure medications, such as phenobarbital and valproic acid
It is essential to inform your doctor or pharmacist about all medications, supplements, and herbal products you are taking before starting Tegretol. They can determine if any interactions may occur and adjust your medication accordingly.

Metabolism done by liver; CYP450 inducer.
Excreted urine 72% feces 28%.
Initial half-life values range from b 25-65 hours, decreasing to 12-17 hours on repeated doses.
Avoid using it in generalize non-convulsive seizures and juvenile Mýoclonic epilepsy. In Asians do check HLA b1502. You can use it in Partial simple/complex seizures, bipolar disorder,Trigeminal neuralgia.

Further reading is required.

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