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Celecoxib Nursing Considerations, Side Effects, and Mechanism of Action Pharmacology for Nurses
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• 08/18/25
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Celecoxib
Generic Name: celecoxib
Trade Name: Celebrex
Indication: osteoarthritis, rheumatoid arthritis, acute pain
Action: decreases pain and inflammation by inhibiting synthesis of prostaglandins
Therapeutic Class: antirrheumatics/NSAID
Pharmacologic Class: none
Nursing Considerations:
use caution with cardiovascular disease
increases risk for MI, CVA, thrombosis
may cause GI bleeding, Stevens-Johnson syndrome, dermatitis
notify provider for new-onset abdominal pain or black stool
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