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Clopidogrel (Plavix)
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• 08/25/25
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Generic Name
Clopidogrel
Trade Name
Plavix
Indication
Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome
Action
Inhibits platelet aggregation
Therapeutic Class
Antiplatelet agent
Pharmacologic Class
Platelet aggregation inhibitors
Nursing Considerations
• May cause GI bleeding, neutropenia, hypercholesterolemia • May increase risk for bleeding in warfarin, aspirin, heparin • Can increase risk for bleeding with garlic, ginkgo, ginger • Monitor for signs of bleeding • Monitor bleeding times • Monitor CBC and platelet count • Discontinue use 5-7 days before surgery
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