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Colchicine for COVID-19: the PRINCIPLE trial
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• 08/18/25
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Read the research: https://doi.org/10.3399/BJGP.2022.0083
In this 1-minute video, Prof. Christopher C Butler explains:
– Colchicine is used regularly for treating gout
– Side effects are gastrointestinal; it is an anti-inflammatory
– Results were available quickly due to the trial design
– Colchicine did not speed up recovery from COVID-19
– The PRINCIPLE trial gives rapid answers within the pandemic
– Trial design is flexible, adapting to different treatments
– PRINCIPLE is transforming research in primary care
Listen to the full podcast interview: https://player.captivate.fm/ep....isode/63de9c41-84f2-
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