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Diphenhydramine Nursing Considerations, Side Effects, Mechanism of Action Pharmacology for Nurses
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• 08/18/25
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Diphenhydramine
Generic Name: diphenhydramine
Trade Name: Benadryl Indication allergy, anaphylaxis, sedation, motion sickness, antitussive
Action: antagonizes effects of histamine, CNS depression
Therapeutic Class: allergy, cold and cough remedy, antihistamine, antitussive
Pharmacologic Class: none
Nursing Considerations:
may cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache
anticholinergic effects (dry mouth, blurred vision, constipation, sedation)
assess purpose of medication prior to giving it
assess allergies, sleep patterns, cough and lung sounds
patient should avoid other over-the-counter cough and cold remedies
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