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Divalproex (Depakote) Nursing Considerations

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Download the cheat: https://bit.ly/50-meds  View the lesson: https://bit.ly/DivalproexDepak....oteNursingConsiderat   Generic Name

Divalproex
Trade Name

Depakote
Indication

Seizures, manic episodes, prevention of headache
Action

Increases the level of GABA (inhibitory neurotransmitter) in CNS
Therapeutic Class

Anticonvulsant, vascular headache suppressants
Pharmacologic Class

None
Nursing Considerations

• May cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity, pancreatitis • Increases risk for bleeding with Warfarin • Use caution with MAOIs • Monitor liver function tests

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