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How to avoid side effects from Accutane (isotretinoin) in 2025 | Dermatologist explains

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I'm John Barbieri, MD, a board-certified dermatologist and acne expert at the Brigham and Women’s Hospital and Harvard Medical School. In this video we will discuss how to prevent common Accutane (isotretinoin) side effects. Although often thought of as a difficult treatment, it doesn’t have to be this way!

However, isotretinoin is not the right treatment for everyone, so make sure to discuss with a healthcare professional before considering whether to take isotretinoin.

#isotretinoin #accutane #acne #dermatologist #expert

Chapters:
0:00 Intro
1:01 Dosing
1:41 Dryness
2:22 Flaring/purging
3:15 Joint Pains
3:44 Lab monitoring
4:21 Depression and inflammatory bowel disease
5:49 Summary

Please subscribe and follow me on other platforms
Twitter/Instagram: @DrJohnBarbieri

References:
Dosing: https://pubmed.ncbi.nlm.nih.gov/21114478/
Omega-3: https://pubmed.ncbi.nlm.nih.gov/32722939/; https://pubmed.ncbi.nlm.nih.gov/30002675/
Antihistamines: https://pubmed.ncbi.nlm.nih.gov/25081735/
Monitoring: https://pubmed.ncbi.nlm.nih.gov/35986616/; https://pubmed.ncbi.nlm.nih.gov/31228528/; https://pubmed.ncbi.nlm.nih.gov/35704293/
Isotretinoin and mood changes: https://pubmed.ncbi.nlm.nih.gov/28291553/
Isotretinoin and inflammatory bowel disease: https://pubmed.ncbi.nlm.nih.gov/37010780/

Disclaimer: This YouTube Channel does not provide any diagnosis, treatment or medical advice and does not replace a visit to your doctor. The statements are not intended to treat, diagnose, cure or prevent disease. See your doctor for medical advice and treatment. My statements on this channel are for informational purposes only.

Thumbnail credit: Sherry Ershadi

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