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HYDROMORPHONE
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• 08/18/25
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It’s an analgesic and opioid
Parenteral doses are 5x more potent than oral
IMMEDIATE RELEASE:
Dose:
Tabs 2 to 4mg q 4-6hrs PRN
Liquid 2.6mg or 1.5mg q3-6hrs
I.V. 0.2-1mg q 2-3hrs
I.V. 0.5mg-1mg/hr infusion
I.M./S.C-with care
I.M is not good because of pain
S.C =0.167 to 4mg/hour continuous infusion
Patient- controlled analgesia (PCA)
Loading dose 0.4mg
Range 0.1-0.4mg
Lockout internal = 10 minutes
Controlled – release capsule e.g.
Hydromorph-contin
Opioid tolerant 12mg-18mg daily or BID or TID
Opioid naïve 3mg q 12hrs
Extended release tabs [Exalgo]
-For opioid tolerant only
-Dose is variable
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