Phentermine is one of the weight loss medications used for short-term periods to treat exogenous obesity in people with a body mass index greater than 30 kg per square meter. It can be used for up to 12 weeks to produce significant weight loss.

Phentermine acts by increasing sympathetic stimulation in the hypothalamus of the brain. It increases neuronal transmission of norepinephrine, which then controls appetite centers within the brain.

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