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Scopolamine (Hyoscine) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings
Scopolamine (Hyoscine) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings
Scopolamine, also known as hyoscine, is an anticholinergic drug primarily used to prevent nausea and vomiting from motion sickness and postoperative recovery. It is available in transdermal, oral, and injectable forms. Its mechanism involves blocking muscarinic acetylcholine receptors in the central and peripheral nervous systems, thereby inhibiting signals that trigger vomiting. Commonly, a transdermal patch (1.5 mg) is applied behind the ear to provide relief for up to 72 hours, while oral or injectable doses range from 0.3 to 0.6 mg every 6–8 hours. Aside from motion sickness, it’s also used for postoperative nausea, irritable bowel syndrome, Parkinson’s-related drooling, and to reduce secretions in palliative care. Side effects include dry mouth, drowsiness, blurred vision, constipation, and more serious effects like confusion or hallucinations in the elderly. It interacts with other anticholinergics, CNS depressants, antidepressants, and MAOIs. Caution is advised in patients with glaucoma, prostatic hypertrophy, or during pregnancy, and users should avoid driving or operating machinery due to potential drowsiness.
#scopolamine #hyoscine #hyoscinebutylbromide #whatisdevil'sbreath(scopolamine)? #devil'sbreath #butylscopolamine #anticholinergic
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