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Triptans Mnemonic for USMLE

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Study this Triptans mnemonic and other mnemonics with Pixorize.

Triptans, which include the archetypal drug sumatriptan, are a class of drugs used to treat headaches. They act as agonists or activators of Serotonin receptors, specifically the serotonin 1B and 1D receptors in the trigeminal nerve and blood vessels in the brain. This agonist activity inhibits the release and delivery of vasoactive peptides that cause inflammation associated with headache disorders. Specifically, triptans are used in the acute treatment of migraine and cluster headaches. An important side effect of taking triptans is the development of coronary vasospasms. As such, these drugs are contraindicated in patients with a history of coronary artery disease or Prinzmetal angina. Another important side effect to remember is serotonin syndrome, which is more common if triptans are given with other serotonin-modulating drugs.

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