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What if one dose of methadone could transform pain management for outpatient surgery?
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• 08/24/25
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💉“What if one dose of methadone could transform pain management for outpatient surgery?”
Today the APSF is diving into a groundbreaking study published in Anesthesiology & summarized by Brian Thomas, JD.
💡 Researchers investigated the use of single-dose intraoperative methadone in next-day discharge outpatient surgeries. Why? To reduce postoperative pain, minimize opioid use, and improve patient satisfaction—all while addressing the opioid crisis.
📊 This randomized, double-blind, dose-finding study compared methadone to shorter-duration opioids like fentanyl and hydromorphone. Patients were randomized to receive methadone or standard practice and monitored closely for pain, sedation, and side effects.
🧪 Results? Methadone reduced in-hospital opioid use significantly and showed a trend toward less home pain and opioid use over 30 days.
🏆 The optimal dose of methadone was 0.25 mg/kg of ideal body weight.
💊 Methadone may offer safer, more effective perioperative pain management for certain outpatient surgeries.
You can learn more here!
https://www.apsf.org/in-the-li....terature/intraoperat
#PatientSafety #Anesthesia #Opioids #Surgery #Methadone
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