Zyprexa Relprevv Vial is a medication used to treat schizophrenia. It is an extended-release olanzapine injection, which is a long-acting form of olanzapine. Olanzapine is part of a group of drugs called atypical antipsychotics, and it helps to restore the balance of certain natural substances in the brain. It's important to talk to your doctor about the risks and benefits of this treatment, especially if it's being used in teenagers. Be sure to also review the Warning and Precautions sections.
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Antipsychotics, also known as neuroleptics or major tranquilizers, are a class of medications primarily used to manage psychotic disorders such as schizophrenia, schizoaffective disorder, and bipolar disorder. These medications work by targeting and modulating neurotransmitter activity in the brain to alleviate symptoms of psychosis, which can include delusions, hallucinations, disorganized thinking, and agitation.

There are two main classes of antipsychotic medications: typical (first-generation) antipsychotics and atypical (second-generation) antipsychotics. Here's an overview of each:

1. First-Generation Antipsychotics (Typical Antipsychotics):
These were the first medications developed to treat psychosis. They primarily target dopamine receptors in the brain, specifically the D2 receptor. Some examples of first-generation antipsychotics include:
- Haloperidol (Haldol)
- Chlorpromazine (Thorazine)
- Fluphenazine (Prolixin)
- Thioridazine (Mellaril)

While these medications are effective at reducing psychotic symptoms, they often come with a higher risk of side effects, such as movement disorders like tardive dyskinesia, which involves involuntary muscle movements.

2. Second-Generation Antipsychotics (Atypical Antipsychotics):
Atypical antipsychotics were developed to address some of the limitations and side effects associated with first-generation antipsychotics. They target multiple neurotransmitter systems, including dopamine and serotonin, and generally have a lower risk of movement-related side effects. Some examples of atypical antipsychotics include:
- Risperidone (Risperdal)
- Olanzapine (Zyprexa)
- Quetiapine (Seroquel)
- Aripiprazole (Abilify)
- Clozapine (Clozaril)
- Lurasidone (Latuda)

Atypical antipsychotics are often preferred due to their reduced risk of movement disorders, but they can still have side effects such as weight gain, metabolic issues, and sedation. Clozapine, in particular, is reserved for treatment-resistant schizophrenia due to its potential to cause a serious blood disorder called agranulocytosis.

Antipsychotic medications are usually prescribed as part of a comprehensive treatment plan that may include therapy, social support, and lifestyle changes. The choice of which antipsychotic to use depends on factors such as the individual's specific diagnosis, symptom severity, and potential side effect profile. Regular monitoring of both symptoms and side effects is crucial when taking these medications.

It's important to note that while antipsychotics can be highly effective in managing psychosis, they are not without potential risks and side effects. Individuals considering or already taking antipsychotics should have ongoing discussions with their healthcare providers to ensure that the benefits of treatment outweigh any potential drawbacks.

Zyprexa, also known as Olanzapine, is used to treat certain mental and mood conditions such as schizophrenia and bipolar disorder. It can also be used along with other medications to treat depression. This medication can help decrease hallucinations, improve clear thinking, and help individuals feel less agitated. It belongs to a class of drugs called atypical antipsychotics and works by helping to restore the balance of certain natural substances in the brain. It is important to talk to your doctor about the risks and benefits of using Zyprexa, especially when considering use in teenagers. Always follow the doctor's recommended dosage and timing for taking this medication.
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🔥 HOT TOPIC: Antipsychotic Drugs

We are kicking off our high-yield year with a HUGE pharmacology review - in just 3 minutes! 💊

The antipsychotic drugs may have similar uses and comparable mechanisms, but their side effect profiles are distinct. A person taking these medications should NOT be overlooked when new symptoms arise.

Put this info to use on your CLERKSHIPS and your EXAMS! 🧠

➖

#medisin #medisinstyle #medicine #medicalstudent #medstudent #pastudent #npstudent #rotations #clerkships #wards #step1 #step2 #usmle #nbme #shelfexam #shelf #testtaking #psych #psychiatry #antipsychotics #medications

It’s taken a long time for me to feel like myself, even a little bit, after discontinuing a psych drug cocktail. It’s happening slowly, but I’m getting there. This is a quick little unscripted video that will hopefully give you a little inspiration as you make your way through the process of discontinuing psychiatric drugs. If you can keep going, no matter how far away from yourself you may feel, you’ll get closer and closer in time to who you were—and are—meant to be.

Thanks for watching!

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Schedule a call ☎️ ☎️ ☎️

Need support and want to set up a one-on-one call with Russell B? Please send an email to this address:

[email protected]

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Note: At the time of this recording, I still have limited mental stamina and am a bit disorganized in my thinking (not in a schizophrenic kind of way, but in a brain-that’s-still-recovering kind of way) so I apologize for the video being a little rambly and not as on-point as it could be. I’ll get better. Thanks again for watching.

Hang in there.

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About Russell B:

I was 11-years-old when I was first taken to a psychiatrist. Like so many children, I was struggling to deal with a stressful home environment. Rather than embarking on the complicated, difficult, and delicate task of thoroughly exploring all of that and attempting to solve the problems at their origins, the psychiatrist instead gave me a diagnosis of Obsessive Compulsive Disorder and promptly prescribed the antidepressant Luvox to treat its “symptoms.”

This sequence of events kickstarted nearly two decades of wandering through psychiatry’s labyrinth of symptom management and prescribing cascades. By the time I was 25, I had received a half-dozen diagnoses, taken countless psychiatric drugs — including ten straight years on antipsychotics — and had more side effects than I could keep up with or manage. I weighed 400 lbs (181 kg), had out-of-control Type 2 diabetes, and felt like I was dying. And honestly, I had felt so bad for so long, I sometimes welcomed it.

I didn’t know where the DSM labels and all the treatments for my supposed “disorders” stopped and I began. I was sad, broken, and worst of all, someone I’d never had the chance to know.

But then I experienced a spark of hope. A light bulb-over-the-brain moment. Maybe I didn’t have to live that way. Even though the belief had been drilled into me for so many of my developing years that coming off the meds would surely seal my doom, something deep inside told me to take a chance and bet big on Russell B. Using this internal guidance, I began a psych drug taper and slowly started coming off every single one of the drugs in a psych drug cocktail: Lexapro, Concerta, Ritalin, Geodon, Klonopin, and Rozerem. None of them were safe. All were on the chopping block.

It took 5 god-awful years to complete the taper and with almost no help from the docs who’d put me on them. But I succeeded.

I’ve been off all meds for 10 years now (as of August 2023) and haven’t seen a psychiatrist since way back in 2009. It’s been a brutally long journey down a nightmarish path. One that was often too dark to see in front of me and littered with steep drops and soul-testing trials. But you know what? I survived. And my life has been improving, slowly but surely, ever since I escaped the house that psychiatry built.

If you’re wandering down the same path, please know you’re not alone. You’re not fated to lose your way – or yourself. You can succeed. We all can.

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Disclaimer:

Any advice given on this channel is not a substitute for medical advice. Please consult with a licensed medical professional before coming off psych drugs.

Thanks for watching Mental Health with Jeremy! I hope i have helped you in your Mental Health journey! Subscribe for more Mental Health and Disorder videos!

Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis, principally in schizophrenia but also in a range of other psychotic disorders

Common Side Effects: Drowsiness, weight gain, dry mouth, stomach upset, QTc interval prolongation, restlessness, dystonia (uncontrollable muscle contractions), tardive dyskinesia (repetitive, involuntary movements), parkinsonism (slowness, stiffness, and tremor), neuroleptic malignant syndrome (rare, but fatal), and seizures.

Huntington disease, Parkinson disease, Lesch-Nyhan syndrome, pervasive developmental disorder are some other conditions where antipsychotics are an option though it is not the primary drug of choice.

First-Generation Antipsychotics:

All dopamine receptor antagonists are available and can be administered in oral form. Except for thioridazine, pimozide, and molindone, all other first-generation antipsychotics can also be given parenterally. Haloperidol and fluphenazine can be delivered in long-acting depot parenteral form.

Second-Generation Antipsychotics:

These can be administered in oral or parenteral forms. Risperidone, olanzapine, aripiprazole, and paliperidone are available as extended-release or long-acting injectable forms. Clozapine, asenapine, and olanzapine are available in the sublingual formulation.




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Olanzapine Pamoate [Olanzapine Long-Acting Injectable] Olanzapine Depot

Long-acting Olanzapine pamoate is a significant advancement in the treatment of psychotic disorders, offering the benefits of extended therapeutic effects and improved patient adherence. This essay provides an in-depth exploration of the pharmacological properties of Olanzapine pamoate, its administration methods, recommended dosing frequency, and its clinical application in the context of psychotic disorders.

Pharmacological Properties

Olanzapine pamoate is a long-acting injectable antipsychotic medication, which provides a depot formulation of Olanzapine. Olanzapine is a second-generation (atypical) antipsychotic medication known for its effectiveness in treating schizophrenia and bipolar disorder. The pharmacological properties of Olanzapine pamoate include:

Extended Half-Life: The depot formulation of Olanzapine pamoate provides an extended half-life, ranging from 21 to 30 days. This prolonged duration of action reduces the frequency of administration and allows for a more stable pharmacokinetic profile.

Mechanism of Action: Olanzapine, the active component released from Olanzapine pamoate, exerts its antipsychotic effects by antagonizing multiple receptors, including dopamine D2, serotonin 5-HT2A, histamine H1, and alpha-1 adrenergic receptors. This broad receptor profile contributes to its efficacy in managing positive and negative symptoms of psychosis.

Administration and Frequency

Olanzapine pamoate is administered through intramuscular injection, typically into the gluteal muscle. The frequency of administration is determined by several factors, including the patient's clinical condition, response to treatment, and the specific indication. Common dosing schedules for Olanzapine pamoate include:

Initial Dosing Phase: The treatment typically begins with a loading dose, given to achieve a therapeutic level of Olanzapine quickly. This initial loading dose generally ranges from 150 mg to 405 mg, divided into two separate injections on the first day. Subsequent injections during this phase may occur every two to four weeks.

Maintenance Dosing: Following the initial dosing phase, patients receive maintenance injections every two to four weeks, depending on the patient's clinical response and side effect profile. These injections can range from 150 mg to 300 mg, with a typical starting dose of 150 mg per month.

Response Assessment: Regular monitoring of the patient's clinical response and side effects is vital. Dosing adjustments can be made to optimize the therapeutic effect while minimizing side effects. The flexibility in dosing frequency allows for a personalized approach to treatment.

Dosing and Titration

The determination of the appropriate dosage of Olanzapine pamoate involves careful consideration of several factors:

Symptom Severity: Patients with severe or acute psychotic symptoms may require a higher initial loading dose to achieve a rapid therapeutic effect. The maintenance dose can be adjusted as needed once symptoms are controlled.

Individual Response: Patient-specific factors, including metabolism, drug sensitivity, and the presence of comorbid conditions, can influence the optimal dosage. Some individuals may respond well to lower doses, while others may require higher doses to achieve therapeutic benefit.

Clinical Application

Olanzapine pamoate has been clinically proven as an effective treatment for schizophrenia and related psychotic disorders. Its extended therapeutic effect, combined with the reduced frequency of administration, can lead to improved treatment adherence and enhanced symptom control. Some of the clinical applications of Olanzapine pamoate include:

Relapse Prevention: Olanzapine pamoate is valuable in preventing relapse in patients of schizophrenia, bipolar, and psychotic patients who have previously responded well to Olanzapine or other antipsychotic medications. It is especially useful for patients at risk of discontinuing oral antipsychotics due to non-adherence..

Long-acting Olanzapine pamoate is a significant advancement in the treatment of psychotic disorders, offering the advantages of extended therapeutic effects, reduced reliance on daily medication regimens, and improved patient adherence. Its pharmacological properties, including a gradual and steady release of Olanzapine and an extended half-life, contribute to its clinical efficacy.

The dosing frequency can be individualized to meet the specific clinical requirements of each patient, allowing for a personalized approach to treatment. Regular monitoring of the patient's clinical response and side effects is essential to optimize treatment outcomes. While Olanzapine pamoate is not without potential side effects, its advantages in terms of extended therapeutic effect make it a valuable addition to contemporary psychiatric practice.

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Olanzapine review 1 year update

I have been on olanzapine since I was 18.

Rudolph Navari, professor of Medicine at Indiana University School of Medicine — South Bend, discusses the effectiveness of olanzapine (Zyprexa) in preventing nausea and vomiting in patients receiving highly emetogenic chemotherapy.

Olanzapine, also known as Zyprexa Zydis, is a medication used to treat certain mental and mood conditions, such as schizophrenia and bipolar disorder. It can also be used in combination with other medications to treat depression. This medication helps to decrease hallucinations, think more clearly and positively, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics and works by helping to restore the balance of certain natural substances in the brain. It is important to talk to your doctor about the risks and benefits of treatment, especially when used in teenagers. The recommended daily dosage and optimal timing of Zyprexa Zydis should be determined by a healthcare professional.
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Olanzapine, also known as Zyprexa Zydis, is a medication used to treat certain mental and mood conditions, such as schizophrenia and bipolar disorder. It can also be used in combination with other medications to treat depression. This medication helps to decrease hallucinations, think more clearly and positively, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics and works by helping to restore the balance of certain natural substances in the brain. It is important to talk to your doctor about the risks and benefits of treatment, especially when used in teenagers. The recommended daily dosage and optimal timing of Zyprexa Zydis should be determined by a healthcare professional.
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Olanzapine is a medication used to treat certain mental and mood conditions, such as schizophrenia and bipolar disorder. It may also be prescribed in combination with other medications to treat depression. This medication can help decrease hallucinations, improve clear thinking and positivity, reduce agitation, and help you take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics and works by helping to restore the balance of certain natural substances in the brain. It is important to talk to your doctor about the risks and benefits of treatment, especially when used by teenagers. It is important to follow your doctor's instructions and take the medication as prescribed.
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Olanzapine is an effective antipsychotic medication, but the associated weight gain is the number one cause of discontinuation, explained Adam Simmons, director of clinical program management, Alkermes. A new drug, ALKS 3831, aims to remove the factor of weight gain from the adherence equation.

Christoph Correll, MD, a professor of psychiatry at Hofstra North Shore-LIJ School of Medicine and expert in pediatric schizophrenia, talks about balancing the benefits of antipsychotic medications with strategies to address their side effects. His core message is simple: encourage healthy living, and always begin with the intervention that poses the smallest risk. He also describes more intensive treatments for the weight gain that often accompanies these medications.

Olanzapine tablets are used for schizophrenia and bipolar mania. It may increase body temperature and needs blood counts.

Disclaimer: The video is intended for educational purposes only, and all the information provided here is neither a substitute for medical advice nor is it recommended for diagnosis or treatment. All efforts are made to provide accurate and error-free information, but the content is variable from time to time due to advances in medical research. Always seek professional medical advice in case of any medical queries, and the videos on this platform do not provide any such suggestions or professional advice.

The five most common side effects on olanzapine Zyprexa discussed.

In this video, I respond to emails from two individuals facing challenges with tapering off psychotropic medications. These questions highlight common struggles, such as withdrawal symptoms, family concerns, and finding the best approach to tapering medications like Zyprexa and other antipsychotics.

I discuss the importance of a slow tapering process, working closely with a healthcare provider, and involving supportive family members in the journey. While I’m not a prescriber, I share personal insights and strategies I would consider if I were in their situation.

Topics Covered:

Coping with withdrawal symptoms (e.g., insomnia, nausea, loss of appetite)
Finding the right tapering plan for long-term medication use
Addressing family concerns about stopping antipsychotics
Building a support system during the tapering process
Disclaimer:
This video is for informational purposes only and not a substitute for professional medical advice. Always consult with your healthcare provider before making changes to your medication regimen.

📩 Have a question? Feel free to reach me at [email protected].

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