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Common Antipsychotic withdrawal symptoms! And how to Avoid!!

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Antipsychotics, previously known as neuroleptics and major tranquilizers, are a class of psychotropic medication primarily used to manage psychosis, principally in schizophrenia but also in a range of other psychotic disorders

Common Side Effects: Drowsiness, weight gain, dry mouth, stomach upset, QTc interval prolongation, restlessness, dystonia (uncontrollable muscle contractions), tardive dyskinesia (repetitive, involuntary movements), parkinsonism (slowness, stiffness, and tremor), neuroleptic malignant syndrome (rare, but fatal), and seizures.

Huntington disease, Parkinson disease, Lesch-Nyhan syndrome, pervasive developmental disorder are some other conditions where antipsychotics are an option though it is not the primary drug of choice.

First-Generation Antipsychotics:

All dopamine receptor antagonists are available and can be administered in oral form. Except for thioridazine, pimozide, and molindone, all other first-generation antipsychotics can also be given parenterally. Haloperidol and fluphenazine can be delivered in long-acting depot parenteral form.

Second-Generation Antipsychotics:

These can be administered in oral or parenteral forms. Risperidone, olanzapine, aripiprazole, and paliperidone are available as extended-release or long-acting injectable forms. Clozapine, asenapine, and olanzapine are available in the sublingual formulation.




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