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Cymbalta
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• 08/18/25
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According to the FDA Cymbalta may treat depression, diabetic related nerve pain, anxiety, fibromyalgia and low back pain. Also known as Duloxetine, the quality of evidence supporting the medicine unfortunately remains of modest to low quality. Actually some studies indicate no benefit when compared to the SSRIs such as Prozac, Zoloft and Lexapro. Similarly effectiveness in fibromyalgia and diabetic neuropathy appears unimpressive. Discontinuing Cymbalta may lead to a peculiar Discontinuation Syndrome associated with headache, dizziness, irritability, sleeplessness, tremor and lack of energy. Some people experience electrical shock like sensations referred to as “brain zaps.”
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