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A 6-month study compared trazodone (50 mg), doxepin (10 mg), and melatonin (3 mg) as alternatives to benzodiazepines for insomnia in 175 psychiatric patients. All improved sleep quality, with trazodone showing slightly better efficacy but more morning grogginess than the others.

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Melatonin, Trazodone, or Doxepin for Sleep Disorders

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