With the number of patients diagnosed with COPD continuing to grow new treatment options are also needed to help these patients maintain a sustainable quality of life.

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The HandiHaler delivers medication in a single-dose dry-powder inhaler to help you breathe easier.

It delivers the medicine Spiriva.

Common Respimat Inhaler Demonstration (Spiriva)

🫁 Olodaterol Pharmacology Overview

Olodaterol is a long-acting β₂-adrenergic receptor agonist (LABA) used for once-daily maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It’s marketed under brand names like Striverdi Respimat and often combined with tiotropium for enhanced bronchodilation.

⚡ Mechanism of Action
β₂-receptor agonism: Activates β₂ receptors in airway smooth muscle, stimulating adenylyl cyclase → ↑ cyclic AMP (cAMP) → bronchodilation.

Selectivity: Highly selective for β₂ over β₁ and β₃ receptors, minimizing cardiac and metabolic side effects.

Rapid onset: Begins working within 5–10 minutes of inhalation.

💊 Pharmacokinetics
Parameter Value
Bioavailability ~30% via inhalation
Peak plasma time 10–20 minutes
Protein binding ~60%
Metabolism Glucuronidation (UGT2B7, UGT1A1, etc.) and O-demethylation (CYP2C9, CYP2C8)
Half-life ~45 hours (inhalation)
Excretion ~53% feces, ~38% urine
🧬 Pharmacodynamics
Bronchodilation: Sustained for 24 hours, allowing once-daily dosing.

Improves FEV₁: Enhances lung function and reduces airflow obstruction.

Reverses bronchoconstriction: Potently counteracts active airway narrowing.

💊 Therapeutic Uses
Indication Role of Olodaterol
COPD (chronic bronchitis/emphysema) Maintenance bronchodilation
Asthma Not approved for monotherapy
Combination therapy Often paired with tiotropium
⚠️ Safety & Side Effects
Common: Nasopharyngitis, bronchitis, cough, dizziness, rash.

Serious risks:

Paradoxical bronchospasm

QT prolongation

Hypokalemia, tachycardia, hypertension

Contraindications:

Monotherapy in asthma

MAOI use within 14 days

Severe cardiovascular disease

🧪 Chemical Profile
Property Value
Molecular Formula C₂₁H₂₆N₂O₅
Molecular Weight 386.45 g/mol
Drug Class Long-acting β₂ agonist
Structure Type Phenylethanolamine derivative
IUPAC Name 6-Hydroxy-8-{(1R)-1-hydroxy-2-[1-(4-methoxy

#Olodaterol

This video covers medications for asthma, COPD, and tuberculosis.

Esse vídeo foi levado ao ar em junho de 2024. Ele compõe as ações realizadas pela Alambra durante o Mês Mundial de Conscientização da Linfangioleiomiomatose, tendo sido gravado pelo Dr. Júlio Abreu, professor titular de Pneumologia da Faculdade de Medicina da Universidade Federal de Juiz de Fora e membro do conselho científico da Alambra.

Welcome to this informative video on COPD drugs. COPD, or chronic obstructive pulmonary disease, is a chronic lung disease that causes breathing difficulties and can be quite debilitating. It affects millions of people worldwide and is the third leading cause of death globally. Fortunately, there are several drugs available that can help manage COPD symptoms and improve quality of life for those affected by this condition.

In this video, we will discuss the most common COPD drugs and how they work to alleviate symptoms.

The first type of COPD drug is bronchodilators. These drugs work by relaxing the muscles in the airways, allowing more air to flow through the lungs. There are two main types of bronchodilators: short-acting and long-acting. Short-acting bronchodilators provide quick relief of symptoms, while long-acting bronchodilators provide more sustained relief over a longer period of time. Some common bronchodilators include albuterol, ipratropium, and tiotropium.

The second type of COPD drug is corticosteroids. These drugs work by reducing inflammation in the airways, which can help improve breathing. Corticosteroids are usually used in combination with bronchodilators for more effective treatment. They are available in both inhaler and pill form. Common corticosteroids used for COPD include fluticasone and budesonide.

The third type of COPD drug is phosphodiesterase-4 inhibitors. These drugs work by reducing inflammation in the lungs and improving breathing. They are usually prescribed for people with severe COPD who have frequent flare-ups. Roflumilast is a common phosphodiesterase-4 inhibitor used for COPD.

Lastly, there are combination drugs that contain both bronchodilators and corticosteroids. These drugs are designed to provide both quick relief and long-term control of COPD symptoms. They are often prescribed for people with moderate to severe COPD who require more aggressive treatment. Common combination drugs include Advair, Symbicort, and Dulera.

It is important to note that while these drugs can be effective in managing COPD symptoms, they do come with potential side effects. It is important to discuss any concerns with your doctor and closely follow their instructions for use.

In conclusion, COPD drugs are an important tool in managing symptoms and improving quality of life for those affected by this condition. By understanding how these drugs work and their potential side effects, you can make informed decisions with your doctor about the best treatment options for you. Thank you for watching this video.
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A recent study links certain commonly prescribed medications — including some antidepressants, bladder medications, antipsychotics and antiepileptic drugs — with an increased risk of dementia. Clinical neuropsychologist Claire Flaherty shares what you should do if you’re on these medications.
Read more about the results of the study here: bit.ly/2JlaZkn

Scott G. Bickel, M.D.

Pediatric grand rounds provide physicians a continuous update on emerging trends in caring for the pediatric patient, including new scientific discoveries that provide the underpinning of current pediatric practice. This activity also will inform physicians about other issues, including professionalism, socioeconomic issues and topics related to the Accreditation Council for Graduate Medical Education core competencies.

At the conclusion of this offering, the participant will be able to:

1) Review the disease characteristics and burden of severe asthma in the pediatric population
2) Discuss strategies for improving control in children with difficult-to-treat asthma
3) Explore the role of adjunctive medications such as low-dose theophylline, anticholinergics and macrolides
4) Appraise the current utility of monoclonal antibodies such as omalizumab and mepolizumab in treating pediatric patients

How a laryngectomee can take Spiriva for COPD

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#pharmacisteducationcorner
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Pulmonology 2 (Obstructive and Restrictive Diseases)

Have you ever wondered what your pill or puffer does or how it works to manage your lung condition? This talk explores the common groups of medications that are used to treat lung disease.

This short video will help you learn how to use a Respimat Inhaler the right way so that you can breathe better. All medicine should be taken under the care of your doctor.

Do you know how to properly use your Respimat Inhaler? Studies show only 1/3 of patients are using their inhalers correctly, 1/3 are performing adequately but not correct and 1/3 are using their inhalers incorrectly.

Respimat inhalation spray is used to control symptoms of chronic obstructive pulmonary disease (COPD) by relaxing your airways and keeping them open. This video will teach you how to properly use a Respimat inhaler (Combivent, Spiriva, Stiolto and Striverdi).

Watch as Glenn demonstrates a conversation between a pharmacist and a customer who has been newly diagnosed with COPD and prescribed Spiriva.

Dr. Huff

0:00 Webinar intro
1:19 John Kolbe - New approaches to asthma
14:46 Nicola Corna - Practical aspects of inhaler devices
43:20 Audience Q&A
53:10 John Kolbe - Case Studies
1:08:25 Audience Q&A

Asthma and COPD result in significant respiratory burden for a number of New Zealanders – particularly within Māori and Pacific communities. One of the mainstays of treatment for these respiratory diseases is the use of inhalers to control and maintain adequate airway function. However, many patients are missing out on appropriate treatment and basic training on how to use their inhalers correctly, contributing to poor disease control, increased severity of symptoms and hospitalisations.

This webinar will be presented by two expert speakers. Professor John Kolbe will discuss new approaches to asthma: appropriate medication, device and patient choice. This will be followed by a case history to illustrate the 2019 GINA guidelines for the treatment of mild asthma.

Practical educational aspects of inhaler devices will be lead by Respiratory Nurse Practitioner Nicola Corna.

Mometasone is also known as the brand names: Asmanex Twisthaler.
Mometasone is used to treat asthma. It is taken 220 mcg daily. It can be given in the evening or in divided doses twice daily.
Some common side effects of mometasone are headache, fatigue, depression, musculoskeletal pain, and upper respiratory infection.
Some less common side effects are abdominal pain, indigestion, nausea, vomiting, anorexia, bruising, infection, influenza, back pain, and ear pain.
Do not take mometasone if:
• You are already taking any corticosteroids.
While taking mometasone, it is important to remember to tell your doctor or pharmacist if you experience any of the following:
• Signs of infection, severe fatigue, irritability, tremors, increased heart rate, confusion, dizziness, sweating, and menstrual pain
• Signs of an allergic reaction (wheezing, chest tightness, fever, itching, bad cough, blue skin color, etc.)
• If you start taking any new medications, supplement or vitamins
• If your condition does not improve or you develop new or worsening symptoms

"Breathe Easier with Spiriva Tiotropium: What You Need to Know"
For centuries, breathing disorders have plagued humanity, from the gasping struggles of asthma to the slow suffocation of chronic obstructive pulmonary disease (COPD). Long ago, healers discovered that certain plants, like Atropa belladonna, contained compounds that could ease breathing difficulties. But these early remedies came with unwanted side effects, making their use a delicate balance between relief and risk.

As medicine advanced, scientists sought better solutions. In the 1970s, ipratropium was developed—a more refined approach to airway relaxation—but it had one drawback: it worked only for a short period, requiring frequent doses. Patients longed for a treatment that would keep their airways open for longer, reducing the need for constant medication.

Enter the pharmaceutical innovators at Boehringer Ingelheim. Throughout the 1980s and 1990s, they worked tirelessly to create a long-acting bronchodilator, one that would provide relief for an entire day. Their research led to the discovery of tiotropium, a breakthrough compound that would change respiratory medicine forever.

Tiotropium, marketed under the brand name Spiriva, became a game-changer. It worked by blocking muscarinic receptors in the lungs, preventing the tightening of airway muscles and allowing patients to breathe more freely. With its once-daily dosing, it gave people with COPD and severe asthma a new sense of control over their lives.

But no drug is perfect. Tiotropium brought relief, but it also came with side effects—dry mouth, throat irritation, and, in rare cases, heart complications. Yet, for millions of patients worldwide, these trade-offs were worth it. Spiriva became a household name in respiratory care, a symbol of progress in the fight against chronic lung diseases.

Today, the legacy of tiotropium continues. It has paved the way for newer combination inhalers, like Spiolto Respimat, which merge its benefits with other lung-friendly compounds. But at its core, the story of tiotropium is a testament to human ingenuity—a story of how science, persistence, and a deep desire to improve lives led to a medication that helps millions breathe a little easier every day.

Esse vídeo foi levado ao ar em junho de 2024. Ele compõe as ações realizadas pela Alambra durante o Mês Mundial de Conscientização da Linfangioleiomiomatose, tendo sido gravado pelo Dr. Júlio Abreu, professor titular de Pneumologia da Faculdade de Medicina da Universidade Federal de Juiz de Fora e membro do conselho científico da Alambra.

Presented on December 14, 2022
Guest Speakers: Alexa McMillan and Lindsay Wetterstrand
 
Developed and hosted by experienced Respiratory Therapists & Educators Alexa McMillan and Lindsay Wetterstrand, our webinar series is designed to help those living with COPD optimize quality of life, covering education components key to effective self-management of your COPD and/or asthma. Guest experts will join hosts to help clarify key topics.

Hello Everyone 😊
in this Video I talked about Asthma And COPD Medications like ( albuterol levalbuterol ipratropium tiotropium Budesonide Mometasone Fluticasone zafirlukast montelukast)
I really hope that this Video helped you !

please help to support this channel to continue making content by subscribing, sharing and liking the videos

Tiotropium, marketed under the brand name Spiriva, is a long-acting muscarinic antagonist (LAMA) used primarily for the maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD). Here's a detailed overview of its pharmacology:

Mechanism of Action
Tiotropium works by blocking muscarinic receptors in the airways, specifically the M3 receptors. This prevents bronchoconstriction and promotes bronchodilation, improving airflow and reducing symptoms such as wheezing and shortness of breath1.

Pharmacokinetics
Absorption: Tiotropium is administered via inhalation, allowing for rapid absorption into the bloodstream.

Distribution: It is distributed throughout the body, with a particular affinity for lung tissue.

Metabolism: Tiotropium is metabolized in the liver by cytochrome P450 enzymes.

Elimination: The drug is primarily excreted in the urine and to a lesser extent in the feces.

Clinical Use
Spiriva is indicated for the long-term, once-daily maintenance treatment of bronchospasm associated with COPD, including chronic bronchitis and emphysema. It helps to reduce exacerbations and improve lung function.

Side Effects
Common side effects of tiotropium include:

Dry mouth

Upper respiratory tract infections

Sinusitis

Pharyngitis

Chest pain

Precautions
Cardiovascular Disease: Caution is advised in patients with pre-existing cardiovascular conditions due to the potential for increased heart rate and blood pressure.

Pregnancy and Lactation: The safety of tiotropium in pregnant or breastfeeding women has not been fully established

#Tiotropium

Everything You Need To Know About SPRAVATO (esketamine) Depression Treatment. Dr. Julia goes over what is Spravato, how Spravato works, is Spravato Ketamine, the side effects of Spravato and barriers to getting Spravato esketamine treatment.

Spravato esketamine has been proven to be highly successful in treating treatment resistant depression and when combined with TMS therapy the results are even greater.

0:00 Intro
1:13 What is Spravato?
2:44 How does Spravato work?
3:49 What can be expected during treatment?
4:48 Side effects of Spravato
5:44 Barriers for getting Spravato treatment
6:44 Getting treated in the Portland Oregon Area.

If you or someone you know is struggling with their mental health, reach out to someone that loves you and let them know what is going on. And if you are in the Portland, Oregon, or Vancouver, Washington area reach out to us.

Phone: (360)777-6708
Email: [email protected]

We are here to help you win your fight against mental illness and get your life back. We know it can feel like you are alone in this, but you are not.

#realtalkmentalhealth​ #mentalhealthvancouverwa​ #dealingwithdepression​ #dealingwithanxiety​ #TMS​ #Transcranialmagneticstimulation​ #mentalhealthawareness​ #mentalhealthportland

This video is a demonstration on how to use the Spiriva HandiHaler Device

Tiotropium, spiriva, long acting, anticholinergic, asthma, OSCE, roze pharm

Are you or a loved one using Spiriva for COPD or asthma? In this video, we break down everything you need to know about Spiriva, including how it works, its benefits, potential side effects, and how to use it properly. Whether you're new to Spiriva or looking for tips on getting the most out of your inhaler, this guide has you covered!

💨 Topics Covered:
✔ What is Spiriva?
✔ How Spiriva helps with COPD & asthma
✔ Side effects and safety precautions
✔ How to use the HandiHaler & Respimat properly
✔ Patient experiences & expert insights

🔔 Don’t forget to like, subscribe, and hit the notification bell for more health and wellness videos!

📌 Disclaimer: This video is for educational purposes only and does not replace professional medical advice. Always consult your doctor before starting or changing any medication.

📢 Have you used Spiriva? Share your experience in the comments below!

Hashtags:
#Spiriva #COPD #Asthma #Inhaler #BreatheBetter #RespiratoryHealth #COPDTreatment #LungHealth #MedicalAdvice #HealthTips

Would you like me to tailor the description for a specific audience, like doctors, patients, or caregivers?

The RX Helper offers prescription assistance for Spiriva and other medications. Find out more information here!

00:26 Why am I taking this medication?
00:39 How should I use this medication?
00:49 What if I miss a dose?
01:02 What side effects can occur?
01:28 What should I tell my HCP before taking this medication?
01:44 Where should I store my medication?

Patient Education Pamphlet:
file:///C:/Users/embau/OneDrive/Desktop/Tiotropium%20and%20Olodaterol.pdf

Spiolto Respimat contains two active substances called tiotropium and olodaterol. These belong to a group of medicines called long-acting bronchodilators. Spiolto Respimat is used to relieve symptoms of chronic obstructive pulmonary disorder in adults, as well as severe asthma.

The active ingredients in Spiolto Respimat work together in two different ways:

1) Tiotropium works in the lungs, where it blocks receptors called muscarinic receptors that are found on the muscle surrounding the airways. This allows the muscle around the airways to relax and the airways to open, making it easier to breathe.

2) Olodaterol acts on special receptors in the lungs. It stimulates these receptors and causes the muscles in the airways to relax. This allows the airways to open.