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ADT plus TAK-700 with ADT plus bicalutamide in patients with newly diagnosed mHSPC
ADT plus TAK-700 with ADT plus bicalutamide in patients with newly diagnosed mHSPC Side Effects 1 Views • 13 days ago

Prof Neeraj Agarwal speaks to ecancer about the SWOG S1216 trial. It investigated ADT plus TAK-700 with ADT plus bicalutamide in patients with newly diagnosed mHSPC.

Initially, he talks about the rationale of the study. Dr Agarwal then describes the methodology and key results of this study. This trial sets a new landmark for survival estimates when patients with mHSPC have access to multiple approved subsequent life-prolonging therapies. Prof Agarwal states that the median OS of 70 months in the control arm (standard ADT) was higher than that reported in contemporary phase 3 trials in this setting, and 16 months higher than originally estimated. In the end, he discussed the impact of these results on the future treatment of this type of prostate cancer.

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CASODEX® (bicalutamide)- carcinoma of the prostate
CASODEX® (bicalutamide)- carcinoma of the prostate Side Effects 1 Views • 13 days ago

#saroarakelians
#casodex
#bicalutamide
#prostatecarcinoma
#astrazeneca
Prostate Cancer Drug Side Effects
Prostate Cancer Drug Side Effects Side Effects 0 Views • 13 days ago

Dr. Snuffy Myers talks about prostate cancer drug side effects. Further discussions with Drs. Maha Hussain, E. David Crawford, Oliver Sartor and Mark Stein appear in March Prostatepedia (http://www.prostatepedia.net/pages/subscribe)

Casodex Tab (bicalutamide) : Common Uses in Prostate Cancer Management
Casodex Tab (bicalutamide) : Common Uses in Prostate Cancer Management Side Effects 0 Views • 13 days ago

What is Casodex Tab?. Casodex Tab, also known by its generic name bicalutamide, is a medication used in the treatment of prostate cancer. It belongs to a class of drugs called anti-androgens, which work by blocking the effects of androgens, such as testosterone, on the prostate gland. Casodex Tab is typically prescribed in combination with other treatments, such as surgery or radiation therapy, to maximize its effectiveness.
How does Casodex Tab work?.
Casodex Tab works by binding to androgen receptors in the body, preventing androgens from attaching to these receptors. Androgens, particularly testosterone, play a crucial role in the growth and development of the prostate gland. In prostate cancer, the cancer cells are stimulated by androgens, causing the tumor to grow. By blocking the effects of androgens, Casodex Tab helps slow down the growth of the tumor and may even cause regression in some cases.
Common uses of Casodex Tab in prostate cancer management.
Casodex Tab is commonly used in the management of prostate cancer at various stages. In early-stage prostate cancer, Casodex Tab may be used as part of a combination therapy with a luteinizing hormone-releasing hormone (LHRH) agonist to suppress the production of testosterone. This combination therapy is known as "combined androgen blockade" and has been shown to improve outcomes in certain patients.
In advanced prostate cancer, Casodex Tab may be used as a monotherapy to slow down the progression of the disease and relieve symptoms. It can help alleviate symptoms such as bone pain, urinary problems, and erectile dysfunction. Casodex Tab may also be used in combination with other treatments, such as radiation therapy or chemotherapy, to enhance their effectiveness.
Casodex Tab dosage and administration.
The dosage of Casodex Tab can vary depending on the individual patient and the stage of prostate cancer being treated. Typically, the recommended dose is 50 mg once daily, either in the morning or evening. It is important to take Casodex Tab exactly as prescribed by the healthcare provider and not to adjust the dosage without medical supervision.
Casodex Tab is available in tablet form and should be swallowed whole with a glass of water. It can be taken with or without food, but it is recommended to take it consistently in the same manner each day. If a dose is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose.
Potential side effects of Casodex Tab.
Like any medication, Casodex Tab may cause side effects in some individuals. Common side effects include hot flashes, breast tenderness or enlargement, fatigue, decreased libido, and erectile dysfunction. These side effects are generally mild to moderate in severity and often improve over time.
In rare cases, Casodex Tab may cause more serious side effects, such as liver problems. Patients should be monitored regularly for any signs of liver dysfunction, including yellowing of the skin or eyes, dark urine, or persistent nausea and vomiting. If any concerning side effects are experienced, it is important to contact a healthcare provider for further evaluation.
Precautions and contraindications for Casodex Tab.
Before starting Casodex Tab, it is important to inform the healthcare provider about any pre-existing medical conditions or medications being taken. Casodex Tab may interact with certain medications, such as blood thinners, and precautions may need to be taken to avoid potential complications.
Casodex Tab is contraindicated in individuals who have a known allergy to bicalutamide or any of its components. It is also not recommended for use in women or children, as it is specifically indicated for the treatment of prostate cancer in men.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



"
What Is Bicalutamide's Relation To Prostate Cancer? - Oncology Support Network
What Is Bicalutamide's Relation To Prostate Cancer? - Oncology Support Network Side Effects 0 Views • 13 days ago

What Is Bicalutamide's Relation To Prostate Cancer? In this informative video, we will discuss the role of bicalutamide in the treatment of prostate cancer. This medication is a nonsteroidal antiandrogen that works by blocking the effects of male hormones, which are essential for the growth of prostate cancer cells. We will explore how bicalutamide is often used in combination with other treatments, specifically gonadotropin-releasing hormone agonists, to enhance its effectiveness.

Additionally, we will cover how bicalutamide functions at a cellular level, its common usage in clinical practice, and the importance of dosage in achieving optimal outcomes. Side effects associated with this medication will also be addressed, providing a comprehensive view of what patients can expect.

Understanding the role of bicalutamide is vital for anyone interested in prostate cancer treatment options. We encourage viewers to consult with healthcare providers to determine the best course of action tailored to individual needs. Join us for this detailed discussion, and subscribe to our channel for more helpful information on oncology and cancer care.

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#Bicalutamide #ProstateCancer #CancerTreatment #AndrogenBlockade #HormonalTherapy #GonadotropinReleasingHormone #Oncology #CancerCare #MensHealth #CancerManagement #ProstateHealth #SideEffects #ClinicalPractice #PatientCare #HealthEducation

About Us: Welcome to the Oncology Support Network, your trusted source for comprehensive information and support in the field of oncology. Our channel is dedicated to empowering patients, caregivers, and healthcare professionals with the latest insights on cancer treatment, research breakthroughs, and wellness strategies. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Overview of Bicalutamide - Casodex (AI voiceover)
Overview of Bicalutamide - Casodex (AI voiceover) Side Effects 0 Views • 13 days ago

In this educational video, we explore bicalutamide, commonly known by its brand name, Casodex. This video provides a comprehensive overview of this medication, its uses, mechanism of action, and potential side effects. Bicalutamide is primarily used in the treatment of prostate cancer, functioning as an anti-androgen that inhibits the effects of male hormones. Our content is designed to inform and educate, ensuring a better understanding of this important drug.

Disclaimer: The information provided in this video is for educational purposes only and should not be considered medical advice. Always consult a healthcare professional for medical concerns or before starting any new treatment. This video does not replace professional medical consultations or prescriptions. While every effort has been made to ensure accuracy, the information may not reflect the most current research or guidelines. Viewer discretion is advised, and your reliance on the information presented is at your own risk.

#Bicalutamide
#Casodex
#ProstateCancer
#CancerTreatment
#MedicalEducation
#Pharmacology
#HealthAwareness
#CancerAwareness
#Oncology
#EducationalVideo
Antiandrogen Monotherapy for mCRPC
Antiandrogen Monotherapy for mCRPC Side Effects 0 Views • 13 days ago

In this segment, the panelists discuss the evolution of treatment for mCRPC, and the use of newer anti-androgen medications as monotherapy.

For more from this discussion, visit http://www.onclive.com/peer-ex....change/treating-mcrp

How Effective Is Bicalutamide? - Oncology Support Network
How Effective Is Bicalutamide? - Oncology Support Network Side Effects 1 Views • 13 days ago

How Effective Is Bicalutamide? In this informative video, we will discuss bicalutamide, a medication used in the treatment of prostate cancer. We'll cover how this non-steroidal antiandrogen works to manage the disease by blocking the effects of testosterone, which is known to promote the growth of prostate cancer cells. You’ll learn about the various stages of prostate cancer where bicalutamide can be beneficial and how it can be used alone or alongside other treatments.

We will also highlight the advantages of bicalutamide, particularly its ability to help maintain the physical capacity and sexual interest of patients, which is essential for their quality of life. Additionally, we will address the typical treatment duration and the importance of consulting healthcare providers to tailor the treatment plan to individual needs.

While discussing the benefits, we will also cover potential side effects that patients should be aware of. Open conversations with healthcare professionals can help manage these side effects effectively. If you or someone close to you is considering this treatment option, this video will provide essential information for making informed decisions.

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#Bicalutamide #ProstateCancer #CancerTreatment #Casodex #HormoneTherapy #CancerCare #Oncology #CancerAwareness #ProstateHealth #PatientSupport #TreatmentOptions #CancerResearch #HealthInformation #QualityOfLife #CancerSurvivorship

About Us: Welcome to the Oncology Support Network, your trusted source for comprehensive information and support in the field of oncology. Our channel is dedicated to empowering patients, caregivers, and healthcare professionals with the latest insights on cancer treatment, research breakthroughs, and wellness strategies. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Pharmacology of Bicalutamide (Casodex) ; Pharmacokinetics, Mechanism of Action, Uses, Effects
Pharmacology of Bicalutamide (Casodex) ; Pharmacokinetics, Mechanism of Action, Uses, Effects Side Effects 0 Views • 13 days ago

Bicalutamide (brand name: Casodex) is a non-steroidal anti-androgen (NSAA) medication primarily used in the treatment of advanced prostate cancer. It is effective as part of androgen deprivation therapy (ADT) due to its ability to block the action of male sex hormones (androgens). Here's an overview of its pharmacology:

Mechanism of Action
Androgen Receptor Antagonist:

Bicalutamide binds competitively to androgen receptors, preventing androgens like testosterone and dihydrotestosterone (DHT) from activating the receptors.

This inhibition blocks androgen-mediated growth signals in androgen-dependent prostate cancer cells, leading to their apoptosis and suppression of tumor growth.

It is often combined with LHRH agonists or antagonists or surgical castration to achieve maximum androgen blockade.

Pharmacokinetics
Administration:

Administered orally as a single daily dose, usually 50 mg.

Absorption:

Well-absorbed after oral administration, with peak plasma concentrations reached within 1–2 hours.

Distribution:

Highly protein-bound and widely distributed in body tissues.

Metabolism:

Extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4.

Excretion:

Excreted primarily in feces, with a small fraction eliminated in the urine.

Half-Life:

The elimination half-life of bicalutamide is approximately 6 days, allowing for once-daily dosing.

Indications
Prostate Cancer:

Used in combination with LHRH agonists (e.g., leuprolide) or after surgical castration to treat advanced or metastatic prostate cancer.

Off-Label Uses (less common):

Management of hirsutism or androgen-related disorders in females.

Adverse Effects
Common Side Effects:

Hot flashes.

Gynecomastia (breast enlargement) and breast tenderness.

Decreased libido and erectile dysfunction.

Nausea and diarrhea.

Hepatotoxicity:

Rare but can cause elevated liver enzymes or hepatocellular damage.

Liver function monitoring is recommended during therapy.

Other Effects:

Fatigue and weakness.

Anemia.

Rash or pruritus.

Contraindications and Precautions
Contraindications:

Females, particularly during pregnancy or lactation, as it can cause harm to the fetus.

Severe hepatic impairment.

Precautions:

Regular monitoring of liver function and complete blood counts is advised.

Use with caution in patients with pre-existing cardiovascular disease due to potential risks of fluid retention or anemia.

Drug Interactions
CYP3A4 Inhibitors:

Drugs like ketoconazole may increase bicalutamide plasma levels, increasing the risk of toxicity.

Anticoagulants (e.g., Warfarin):

Bicalutamide may enhance the effects of warfarin, increasing the risk of bleeding.

Other Hepatotoxic Drugs:

Combining with drugs that have hepatotoxic potential may exacerbate liver toxicity.

Clinical Considerations
Bicalutamide is primarily used for maximum androgen blockade (MAB) in prostate cancer treatment, aiming to enhance the efficacy of LHRH analogs.

Its favorable side effect profile compared to older anti-androgens (e.g., flutamide) makes it a preferred choice in many cases.

#Bicalutamide
Cardiovascular Side Effects of Advanced Disease Therapies
Cardiovascular Side Effects of Advanced Disease Therapies Side Effects 1 Views • 13 days ago

William K. Oh, MD, examines cardiovascular side effects associated with hormonal and chemotherapeutic therapies for advanced prostate cancer.

#urology #urologist #prostatecancer #oncology #androgendeprivationtherapy
Understanding Intermittent Hormone Therapy For #ProstateCancer | #MarkScholzMD #AlexScholz #PCRI
Understanding Intermittent Hormone Therapy For #ProstateCancer | #MarkScholzMD #AlexScholz #PCRI Side Effects 1 Views • 13 days ago

Embark Clinical Trial: Improved Outcomes with Enzalutamide in Biochemically Recurrent Prostate Cancer: https://www.nejm.org/doi/full/....10.1056/NEJMoa230397

Donate to PCRI: https://pcri.org/donate/
For more information, visit https://pcri.org

1:13 What is intermittent hormone therapy, and how does it work?
4:43 How is intermittent hormone therapy administered?
6:12 Is letting a patient's PSA rise to 2 advisable during therapy?
8:24 Is nine months a reasonable treatment period before considering a holiday?
9:12 How often is PSA checked during intermittent hormone therapy?
9:33 Does the type of therapy matter during intermittent hormone therapy?
11:13 Is intermittent hormone therapy complicated for insurance coverage?
12:00 How much do side effects usually recede during the holiday period?
13:45 How long can intermittent hormone therapy last?
14:45 Alex's conclusions
15:13 If you need help

Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org

To learn more about prostate cancer, visit http://www.pcri.org

Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: https://pcri.org/join

Who we are:

The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.

Supportive measures for side effects of hormonal therapy on sexual activity in prostate cancer
Supportive measures for side effects of hormonal therapy on sexual activity in prostate cancer Side Effects 1 Views • 13 days ago

Stephen Freedland, MD, Cedars-Sinai Medical Center, Los Angeles, CA, gives an overview of supportive measures used to mitigate the side effects of combination therapy (enzalutamide and leuprolide) on sexual activity in high-risk biochemically recurrent non-metastatic prostate cancer. Dr Freedland highlights the importance of shared decision making when starting treatment to offer patients an educated choice between this combination therapy and enzalutamide monotherapy, which has fewer side effects on erectile function. Additionally there are a variety of treatments for erectile dysfunction which can be offered to affected patients to mitigate this adverse effect and maintain their quality of life. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
Supportive measures for side effects of hormonal therapy on sexual activity in prostate cancer
Supportive measures for side effects of hormonal therapy on sexual activity in prostate cancer Side Effects 1 Views • 13 days ago

Stephen Freedland, MD, Cedars-Sinai Medical Center, Los Angeles, CA, gives an overview of supportive measures used to mitigate the side effects of combination therapy (enzalutamide and leuprolide) on sexual activity in high-risk biochemically recurrent non-metastatic prostate cancer. Dr Freedland highlights the importance of shared decision making when starting treatment to offer patients an educated choice between this combination therapy and enzalutamide monotherapy, which has fewer side effects on erectile function. Additionally there are a variety of treatments for erectile dysfunction which can be offered to affected patients to mitigate this adverse effect and maintain their quality of life. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
Understanding Intermittent Hormone Therapy For #ProstateCancer | #MarkScholzMD #AlexScholz #PCRI
Understanding Intermittent Hormone Therapy For #ProstateCancer | #MarkScholzMD #AlexScholz #PCRI Side Effects 1 Views • 13 days ago

Embark Clinical Trial: Improved Outcomes with Enzalutamide in Biochemically Recurrent Prostate Cancer: https://www.nejm.org/doi/full/....10.1056/NEJMoa230397

Donate to PCRI: https://pcri.org/donate/
For more information, visit https://pcri.org

1:13 What is intermittent hormone therapy, and how does it work?
4:43 How is intermittent hormone therapy administered?
6:12 Is letting a patient's PSA rise to 2 advisable during therapy?
8:24 Is nine months a reasonable treatment period before considering a holiday?
9:12 How often is PSA checked during intermittent hormone therapy?
9:33 Does the type of therapy matter during intermittent hormone therapy?
11:13 Is intermittent hormone therapy complicated for insurance coverage?
12:00 How much do side effects usually recede during the holiday period?
13:45 How long can intermittent hormone therapy last?
14:45 Alex's conclusions
15:13 If you need help

Don't know your stage? Take the quiz: visit http://www.prostatecancerstaging.org

To learn more about prostate cancer, visit http://www.pcri.org

Sign up for our newsletter here to receive the latest updates on prostate cancer and the PCRI: https://pcri.org/join

Who we are:

The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better-individualized care. Feel free to explore our website at pcri.org or contact our free helpline with any questions that you have at pcri.org/helpline. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.

Bicalutamide (Casodex) - Drug Rx Information
Bicalutamide (Casodex) - Drug Rx Information Side Effects 1 Views • 13 days ago

General information regarding Bicalutamide (Casodex). Content created leveraging AI with the goal of bridging access across communities. Please flag any suggestions or errors in the comment section. Thank you!
Which is Better - Surgery vs. Radiation for Prostate Cancer?
Which is Better - Surgery vs. Radiation for Prostate Cancer? Side Effects 1 Views • 13 days ago

PCRI’s Executive Director, Mark Scholz, MD, explains why there has been a surgery vs. radiation controversy, describes the pertinent risks and considerations when deciding between the two treatments, and explains why he thinks radiation is usually going to be the preferable option, all things considered.

0:43 The main reason why there is a controversy about whether surgery or radiation is better for treating prostate cancer is that as recently as 10-15 years ago the technology for radiation was significantly less effective and more toxic than it is today. There were also fewer options for salvage therapy after radiation in the event of a relapse. Since then, radiation technology has advanced significantly, but the dialogue has been comparatively mired. Today, radiation can be precisely delivered, and radiation is achieving even better cure rates than surgery.

1:59 Surgeons are constrained by the fact that the bladder and the rectum are within millimeters of the prostate. They cannot cut a margin around the gland. Radiation oncologists are not limited in this way.

2:21 External beam radiation has a cure rate about as good as surgery, and radioactive seed implants have even better cure rates than surgery.

2:33 Most men will live for a very long time after being treated for prostate cancer, and so it is important to consider the side effects of each treatment, especially now that they all have comparable cure rates.

2:54 There is a risk of sexual dysfunction with both surgery and radiation, however, the rate of impotence after surgery is significantly higher than after radiation.

3:15 There is a risk of incontinence with surgery that is almost non-existent with radiation. An operation performed by a top surgeon on an ideal candidate has about a 5-10% risk of causing incontinence, and that is with the best possible conditions. Stress incontinence occurs in around 50% of men, and ejaculation of urine occurs in about 20% of men.

4:00 Rectum burns used to be a concerning side effect of radiation, but that risk has been eliminated with the advent of SpaceOAR, a gel that separates the prostate from the rectum and protects it from radiation.

Don’t know your stage? Take the quiz: Visit http://www.prostatecancerstaging.org

To learn more about prostate cancer visit http://www.pcri.org

To download the free Staging Guide visit http://www.pcri.org/prostate-cancer-s...

Who we are:

The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.

The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.

#ProstateCancer #Prostate #MarkScholzMD

Lumateperone capsules | common side effects of lumateperone capsules
Lumateperone capsules | common side effects of lumateperone capsules Side Effects 2 Views • 13 days ago

This video explains some common side effects of lumateperone capsules.

@ProfessorTushar
🛑WHAT TO KNOW ABOUT CAPLYTA LUMATEPERONE 👉 Mental Health
🛑WHAT TO KNOW ABOUT CAPLYTA LUMATEPERONE 👉 Mental Health Side Effects 1 Views • 13 days ago

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My Experience, Response, Review with Caplyta (Lumateperone), A New Atypical Antipsychotic
My Experience, Response, Review with Caplyta (Lumateperone), A New Atypical Antipsychotic Side Effects 0 Views • 13 days ago

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My Experience, Response, Review with Caplyta (Lumateperone), A New Atypical Antipsychotic

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Call 1-800-273-8255
Available 24 hours everyday

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http://www.twitter.com/beyondbipolari

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#mentalhealth #bipolar #suicide #depression #anxiety #mentalhealthawareness #borderline #psychology #psychiatry #therapy #mania #lithium #schizophrenia #personalitydisorder #vlog #anorexia #addiction #adoption #adoptee #koreanadoptee #kad #education #inspirational #nami #hospitalized #drugs #psychosis #mentaldisorder

My Experience, Response, Review with Caplyta (Lumateperone), A New Atypical Antipsychotic [Update]
My Experience, Response, Review with Caplyta (Lumateperone), A New Atypical Antipsychotic [Update] Side Effects 1 Views • 13 days ago

My Experience, Response, Review with Cymbalta (Duloxetine), a SNRI Class Antidepressant

♪

Credits:

Travis Charles Balitz: Video & Photo Editor
Kyle Balitz: Video & Photo Editor
Nancie Cha: Director | Videographer

♪

Websites:

Travis Balitz:
https://lift.bio/manhopark
http://www.travisbalitz.com/

Kyle Balitz:
http://lift.bio/krbalitz
http://www.kylebalitz.com

♪

National Suicide Prevention Lifeline
Call 1-800-273-8255
Available 24 hours everyday

♪

My name is Travis Balitz. I have been living with Bipolar Disorder since 2008. I have had many other diagnosis such as anxiety, depression, schizoaffective disorder and bipolar type 2 . I am currently diagnosed with bipolar type 1. There have been many ups and downs in my life. Here on this channel I am advocate for Mental Health. I share my experiences, good and bad and in between. I also give advice and share my general experience with hospitalizations, partial hospitalizations, group homes (IRTS), dialectical behavioral therapy, personal therapy, psychiatric experiences and my knowledge on all of the medications I have been on. I hope you can learn something from my channel. Also do not be afraid to reach out if you are in a dire situation. Please contact the suicide hotline or text if you are at a risk for your mental health. Number is here: 988. Thank you.

♪

Please check out my links to stream and download my music below. I not only create songs but instrumentals and beats, so make sure to check them out below as well. Also, Kyle are pianists and do covers on our channel link below.

♪

Buy my music cds today and donate! Go to 2uo7rax.bandcamp.com and click "Sounds Of Silence" and/or "Spiri7rax" to buy physical cds of these two albums.

1. "Sounds Of Silence" - Original New Age Piano Music
2. "Spiri7rax" - Original Orchestral Music

One CD is $5.00 USD + SH
Two CDs are $8.00 USD + SH

♪

Instrumentals Streaming:

Spotify
https://open.spotify.com/artis....t/2vatDbJ6i94dt6K00d

Apple Music:
https://music.apple.com/us/art....ist/2uo7rax/74226959

Instrumentals Download:
http://www.2uo7rax.com
http://2uo7rax.bandcamp.com

Instrumentals YouTube Page:
http://www.youtube.com/2uo7rax

Instrumentals Facebook Page:
http://www.facebook.com/2uo7rax

♪

Beats Streaming:

Spotify:
https://open.spotify.com/artis....t/5G0kCeFgTbGiBwZLwk

Apple Music:
https://music.apple.com/us/art....ist/2uo8eats/1674358

Beats Download:
http://www.2uo8eats.com
http://2uo8eats.bandcamp.com

Beats YouTube Page:
http://www.youtube.com/2uo8eats

Beats Facebook Page:
http://www.facebook.com/2uo8eats

♪

Songs Streaming:

Spotify:
https://open.spotify.com/artis....t/0KanARhvp4M7noJzBv

Apple Music:
https://music.apple.com/us/art....ist/travist/16154413

Songs Download:
http://www.realgroupstation.com
http://realgroupstation.bandcamp.com

Songs YouTube Page:
http://www.youtube.com/realgroupstation

Songs Facebook Page:
http://www.facebook.com/realgroupstation

♪

Piano Covers:

Piano Covers YouTube Page:
https://www.youtube.com/c/2uo12iano

Piano Covers Facebook Page:
http://www.facebook.com/2uo12iano

♪

I am also a professional artist that specializes in hyperrealistic portrait drawings, airbrush portraits, and abstract acrylic artwork.

To view my artwork and or ask for inquiries or estimates please visit: http://www.travisbalitz.com/artwork or @artworkbytravis

♪

IG Pages:

My Music IG: @its.travist
My Photo IG: @travis.balitz
My Artwork IG: @artworkbytravis
My Fitness IG: beyondbipolarfitness

TikTok: @its.travist

♪

If you are are interested in song writing, sound engineering and or sound production services, feel free leave a message via YouTube or email. To request rates, terms, conditions, and to discuss business/freelancing opportunities, please contact us by email at REALGroupStation (at) Gmail [dot] com

♪

http://www.beyondbipolarblog.com
https://anchor.fm/beyondbipolarblog
http://www.facebook.com/beyondbipolarblog
http://www.twitter.com/beyondbipolari

♪

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#mentalhealth #bipolar #suicide #depression #anxiety #mentalhealthawareness #borderline #psychology #psychiatry #therapy #mania #lithium #schizophrenia #schizoaffectivedisorder #personalitydisorder #vlog #anorexia #addiction #adoption #adoptee #koreanadoptee #kad #education #inspirational #nami #hospitalized #drugs #psychosis #mentaldisorder #disabled #fitness #workout #bodybuilding #weightloss

Bipolar Disorder vs Depression - 5 Signs You're Likely Bipolar
Bipolar Disorder vs Depression - 5 Signs You're Likely Bipolar Side Effects 1 Views • 13 days ago

Bipolar disorder vs. depression? It's not always easy to tell. The symptoms of bipolar disorder include depression symptoms. So you may wonder, am I depressed or bipolar? Many people will be diagnosed with depression for years before they have a manic or hypomanic episode, which is the main sign that you have bipolar disorder vs depression. In this video I give you 5 signs that your depression is more likely part of bipolar disorder and not unipolar depression.


References:
Aiken, Chris B. et al. The Bipolarity index: a clinician-rated measure of diagnostic confidence. Journal of Affective Disorders , Volume 177 , 59 - 64

I upload every Wednesday at 9am, and sometimes have extra videos in between. Subscribe to my channel so you don't miss a video https://goo.gl/DFfT33

CAPLYTA - Generic Name, Brand Names, How to use, Precautions, Side Effects
CAPLYTA - Generic Name, Brand Names, How to use, Precautions, Side Effects Side Effects 1 Views • 13 days ago

#medicalknowledgeonline
CONTENTS,
Generic Name, Brand Names, What is ?, Vital information, Dosage info,
Before taking this medicine (Precautions ), How to use ,
Miss a dose, Overdose , Stop or Avoid Taking ,
Side Effects, Other Drugs Will Affect,
#medicalknowledgeonline
TOPICS
1. ANATOMY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
2. PHYSIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
3. DISEASES – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
4. PUBLIC HEALTH- Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
5. Rx – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
6. LABORATORY TEST – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
7. MEDICAL IMAGING – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
8. SURGICAL AND MEDICAL PROCEDURES – topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
9. MICROBIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
10. BIOCHEMISTRY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
11. NUTRITION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
12. HEALTH TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
13. MEDICAL & SURGICAL – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
14. PAEDIATRICS / CHILD HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
15. MENTAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
16. MATERNAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
17. COMMUNITY HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
18. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
19. BIOSTATISTICS – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
20. PATHOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
21. NURSING EDUCATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
22. HOSPITAL MANAGEMENT AND HEALTH CARE ADMINISTRATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
23. NURSING RESEARCH – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
24. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
25. PHARMACOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
26. PUBLIC HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
27. INTERNATIONAL DAYS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
28. NURSING - TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
#medicalknowledgeonline

Vraylar (Cariprazine) For Schizophrenia And Bipolar Disorder (Medication Review)
Vraylar (Cariprazine) For Schizophrenia And Bipolar Disorder (Medication Review) Side Effects 0 Views • 13 days ago

Vraylar (Cariprazine) is an antipsychotic that is commonly prescribed in psychiatry for bipolar disorder and schizophrenia. This video discusses its uses, dosing, side effects, and more! *** MORE VIDEOS ON ANTIPSYCHOTIC MEDICATIONS ➡️ https://www.youtube.com/playli....st?list=PLQgOA4hcgBV

⏰ TIMESTAMP ⏰
0:00 Vraylar Vs Cariprazine
0:14 How Vraylar Works
0:25 What Vraylar Treats
0:47 Vraylar Dosing
1:12 How Long Until Vraylar Works
1:29 Side Effects Of Vraylar
2:34 Vraylar Length Of Treatment
2:50 How To Stop Vraylar

Please SUBSCRIBE for new videos every week ▶ https://youtube.com/channel/UC....H_qZq0BRy2Tv54I_n7rm

If you have any topics that you'd like to hear more about, please let me know because this channel was made for YOU AND YOUR FAMILY!

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This information is for educational and informational purposes only and solely as a self-help tool for your own use. I am not providing medical, psychological, or nutrition therapy advice. Watching the videos or getting answers to comments/questions does not establish a doctor-patient relationship. You should not use this information to diagnose or treat any health problems or illnesses without consulting your own medical practitioner. Always seek the advice of your own medical practitioner and/or mental health provider about your specific health situation. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately.

Text HOME to 741741 to connect with a crisis counselor (US and Canada)
National Suicide Prevention Hotline 1-800-273-TALK (8255)

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A Day in the Life: Caplyta Side effects
A Day in the Life: Caplyta Side effects Side Effects 0 Views • 13 days ago

Caplyta (Lumateperone) a New Antipsychotic for Schizophrenia and Depressive Episodes in Bipolar
Caplyta (Lumateperone) a New Antipsychotic for Schizophrenia and Depressive Episodes in Bipolar Side Effects 1 Views • 13 days ago

0:00 Introduction
0:23 Mechanism of action
1:04 Possible side effects
Caplyta! My overall review and impressions of it. #psychiatry #pharmacology
Caplyta! My overall review and impressions of it. #psychiatry #pharmacology Side Effects 0 Views • 13 days ago

Top 3 Things You MUST Know About Caplyta
Top 3 Things You MUST Know About Caplyta Side Effects 1 Views • 13 days ago

Got questions about Caplyta (lumateperone)? You're not alone and this video delivers real answers to the top 10 things people want to know. Whether you're newly prescribed or just curious, we’ll uncover how Caplyta works, who it’s for, what side effects to watch for, and what makes it different from older antipsychotics.

Plus, find out what happens if you miss a dose, what not to mix it with, and how long treatment might last. And here’s something most people miss: what to do with unused meds (Hint: it could put cash in your pocket 💸).

Watch this to get the facts your doctor might not have time to explain.

Do you have unused Caplyta or other surplus medications? Don't let them go to waste! At "I Buy Diabetic Supply", we help people get cash for their unused CGM, COPD and other medications.

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#Caplyta #MentalHealthMatters #BipolarDepression #SchizophreniaHelp #MedicationGuide #PharmaFacts #UnusedMeds #HealthcareTips

⚠️ DISCLAIMER: This video is for educational purposes only and should not be considered as medical advice. Always consult your healthcare provider for personalized guidance regarding your health or medications.

Secrets of the side effects of Caplyta
Secrets of the side effects of Caplyta Side Effects 0 Views • 13 days ago

Secrets of the side effects of Caplyta
*Common (1% to 10% of patients)**

* Agitation
* Akathisia (restlessness)
* Anxiety
* Constipation
* Diarrhea
* Drowsiness
* Dry mouth
* Nausea
* Tremor
* Vomiting

**Less common (less than 1% of patients)**

* Abnormal thoughts
* Aggression
* Allergic reactions
* Anxiety
* Bipolar disorder (worsening)
* Chest pain
* Confusion
* Dizziness
* Dysphagia (difficulty swallowing)
* Eczema
* Erectile dysfunction
* Excessive sweating
* Fatigue
* Fever
* Hallucinations
* Headache
* Heart palpitations
* Hyperglycemia (high blood sugar)
* Insomnia
* Irritability
* Liver damage
* Low blood pressure
* Muscle spasms
* Nightmares
* Orthostatic hypotension (drop in blood pressure when standing up)
* Pain
* Pruritus (itching)
* Rash
* Respiratory distress
* Seizures
* Sleepwalking
* Stupor
* Tardive dyskinesia (involuntary muscle movements)
* Tics
* Urinary retention

**Rare (less than 0.1% of patients)**

* Anaphylaxis (severe allergic reaction)
* Cardiac arrest
* Cerebral hemorrhage (bleeding in the brain)
* Death
* Guillain-Barré syndrome (a serious neurological disorder)
* Malignant neuroleptic syndrome (a life-threatening reaction to antipsychotics)
* Myocardial infarction (heart attack)
* Neuroleptic malignant syndrome (a serious reaction to antipsychotics)
* Stroke
Why Caplyta is the Game-Changing Medication for Mental Health: Exploring its Benefits
Why Caplyta is the Game-Changing Medication for Mental Health: Exploring its Benefits Side Effects 2 Views • 13 days ago

Caplyta represents a significant breakthrough in the field of mental health medication. Unlike traditional treatments, Caplyta specifically targets specific receptors in the brain, reducing the risk of unwanted side effects. This targeted approach allows for a more precise and effective treatment, tailored to the individual's unique needs.
One of the key factors that sets Caplyta apart is its ability to deliver therapeutic relief without causing weight gain, sedation, or movement disorders commonly associated with other medications. This is a game-changer for individuals who have struggled with these side effects in the past, as it allows them to focus on their mental well-being without the added burden of physical discomfort.
Additionally, Caplyta's formulation is designed to provide long-lasting symptom relief, reducing the need for frequent dose adjustments or additional medications. This stability in treatment allows individuals to regain control over their lives and pursue their goals and aspirations with confidence.
Benefits of Caplyta medication.
The benefits of Caplyta medication extend beyond its ability to target specific receptors and avoid debilitating side effects. This groundbreaking medication offers a range of advantages that have transformed the lives of countless individuals struggling with mental health conditions.
One of the primary benefits of Caplyta is its effectiveness in treating a variety of symptoms associated with mood disorders, psychosis, and schizophrenia. Clinical trials have shown significant improvements in symptoms such as hallucinations, delusions, disorganized thinking, and emotional instability. This comprehensive approach to treatment allows individuals to experience relief across multiple aspects of their condition, leading to a better quality of life overall.
Another notable benefit of Caplyta is its ability to improve cognitive function in individuals with mental health conditions. Cognitive impairments are common in conditions such as schizophrenia, making it difficult for individuals to think clearly, concentrate, or remember information. Caplyta's unique formulation has been shown to enhance cognitive abilities, enabling individuals to regain control over their thought processes and engage more effectively in their daily lives.
Furthermore, Caplyta has demonstrated a lower risk of drug-drug interactions compared to other medications. This is particularly important for individuals who may be taking multiple medications to manage their mental health condition and other medical issues. With Caplyta, individuals can have peace of mind knowing that their treatment is less likely to be compromised by potential interactions.
Clinical studies and research supporting Caplyta's effectiveness.
The effectiveness of Caplyta as a game-changing medication for mental health treatment is not simply anecdotal. Extensive clinical studies and research have been conducted to validate its efficacy and safety.
Multiple randomized controlled trials involving thousands of participants have consistently shown that Caplyta is superior to placebo in reducing symptoms related to mood disorders, psychosis, and schizophrenia. These studies have included diverse patient populations, ensuring that the benefits of Caplyta extend across different demographics.
In addition to symptom improvement, research has also highlighted the positive impact of Caplyta on overall functioning and quality of life. Individuals taking Caplyta reported significant improvements in their ability to engage in social interactions, maintain employment, and pursue personal goals. This holistic approach to treatment is a testament to the transformative effects of Caplyta on individuals' lives.
How Caplyta is changing the landscape of mental health treatment.
Caplyta's introduction into the field of mental health medication has undoubtedly reshaped the landscape of treatment options. Its unique formulation and targeted approach have challenged traditional methods, offering a new paradigm for individuals and healthcare professionals alike.
The ability of Caplyta to provide relief without debilitating side effects has given individuals hope and confidence in their treatment journey. The fear of weight gain, sedation, or movement disorders no longer hinders individuals from seeking the help they need.

"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.
Caplyta
Caplyta Side Effects 0 Views • 13 days ago

Caplyta occupies the dubious honor of being the 13th second generation antipsychotic granted FDA approval. Other members of the family include Zyprexa, Abilify, Risperdal and Rexulti. Unlike some of the others, Caplyta is only marketed to treat symptoms of schizophrenia. Caplyta is an oral drug administered once daily with meals. The dose is 42 mg.

Schizophrenia includes positive and negative symptoms. The positive symptoms of delusions and hallucinations may improve with Caplyta but the drug appears less likely to help the negative symptoms of apathy, social withdrawal and blunted affect.

Short term trials involving relatively few patients demonstrate relatively unremarkable improvement. Caplyta does not appear to offer any distinct or unique advantages compared to the other 2nd generation antipsychotics. For the cash price of nearly $1600 a month one would expect special benefits. The cash price of other popular generic antipsychotics may be as low as $10 a month.

Caplyta may interact with a variety of other medicines. A special black box warning cautions against use in elderly patients with dementia. Sedation and somnolence occur in up to 1 in 4 patients. Difficulty swallowing due to esophageal problems may lead to aspiration. Dystonia presents as spasm of the neck muscles, tightness of the throat and difficulty breathing.

Unusual movements of the mouth, lips, tongue and eyelids known as tardive dyskinesia may or may not resolve with discontinuation of therapy. Metabolic changes include increase in blood sugar, weight gain and elevation of serum lipids. The white blood count may decrease and potentially serious declines in blood pressure on standing also known as orthostatic hypotension expose the patient to potential falls and fractures. Seizures may occur.
Caplyta (Lumateperone): EVERYTHING you NEED to Know!
Caplyta (Lumateperone): EVERYTHING you NEED to Know! Side Effects 2 Views • 13 days ago

🙋🏽‍♀️ Join this channel to access exclusive LIVES, priority comments/questions answered, and more!:
https://www.youtube.com/channe....l/UCMzNgkZdW1dON-ZNe

📚 Useful Resources:
Stahl's Prescribing Guide: https://amzn.to/4bjHlHe
Deprescribing Guide: https://amzn.to/3XBkIuA
Drug Interaction Checker-https://www.drugs.com/drug_interactions.html
Brain Food Report- https://www.levelheadedmind.com/brainfoodreport
Neurotransmitter Questionnaire- https://www.levelheadedmind.co....m/neurotransmitter-a
Recommended Reading: https://www.levelheadedmind.com/books

🎥 This video was edited by:
Rahul Kanchi https://www.linkedin.com/in/rahulkanchi24/

🚑 If you are in a mental health crisis, please dial 9-8-8 from the U.S. Or text HOME to 741741 and connect to a crisis counselor.
You can find a list of international crisis lines here: https://blog.opencounseling.com/suicide-hotlines/

References:
DailyMed - CAPLYTA- lumateperone capsule. (updated 2023). Dailymed.nlm.nih.gov. https://dailymed.nlm.nih.gov/d....ailymed/drugInfo.cfm

Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.

Stahl,S. (2021). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 7th Ed. Cambridge University Press.

Tarzian M, Ndrio M, Chique B, Serai J, Thalackal B, Lau J, Fakoya AO. Illuminating Hope for Mental Health: A Drug Review on Lumateperone. Cureus. 2023 Sep 28;15(9):e46143. doi: 10.7759/cureus.46143. PMID: 37900490; PMCID: PMC10612995.

Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own healthcare provider for proper diagnosis and treatment.

Note: This video is not sponsored. Some of the links provided are affiliate links, meaning I may earn a small commission from purchases made through those links.

Caplyta (lumateperone) Uses, How It Works, and Common Side Effects
Caplyta (lumateperone) Uses, How It Works, and Common Side Effects Side Effects 0 Views • 13 days ago

Millions of people have schizophrenia and bipolar disorder. For many, antipsychotics are an effective treatment option.

0:17 How it works
0:39 Side effects
1:01 Tips

Learn more: https://www.drugs.com/caplyta.html

A newer antipsychotic is Caplyta. It works differently than other antipsychotics, and has a unique side effect profile.

Caplyta is used to treat adults with schizophrenia or bipolar depression. It comes as a capsule that’s taken by mouth once a day.

Caplyta works by affecting neurotransmitters in the brain, including dopamine, serotonin, and glutamate. These actions help relieve symptoms such as hallucinations and delusions associated with schizophrenia, and low mood in people with bipolar depression.

Common side effects of Caplyta may include sleepiness, dizziness, nausea, and dry mouth. Caplyta does not usually cause weight gain as a side effect, unlike some other antipsychotics.

In fact, some people have lost weight during treatment with Caplyta. Based on animal studies, this medication might cause fertility problems in males and females.

Caplyta works gradually, so you may not notice immediate effects. Stay consistent—full benefits can take weeks, but taking it daily helps you get the best results of improved symptoms and severity.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Always consult with your healthcare provider.

To learn more about any medication, or medical treatment, visit https://www.drugs.com

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Mavacamten: A Revolutionary Treatment for Obstructive Hypertrophic Cardiomyopathy cas: 1642288-47-8
Mavacamten: A Revolutionary Treatment for Obstructive Hypertrophic Cardiomyopathy cas: 1642288-47-8 Side Effects 1 Views • 13 days ago

Mavacamten is a medication that was developed for the treatment of symptomatic obstructive hypertrophic cardiomyopathy (oHCM), a condition in which the heart muscle becomes abnormally thick, making it harder for the heart to pump blood.

Here's a brief overview:

Mechanism of Action: Mavacamten is a myosin inhibitor. It works by targeting the heart muscle contractility and reducing the excessive contractile force in oHCM, which in turn can help reduce the obstruction and improve symptoms.

Indication: It's primarily indicated for patients with symptomatic oHCM, a subset of hypertrophic cardiomyopathy where there's an obstruction to the outflow of blood from the heart due to the thickened heart muscle.

Benefits: Clinical trials have shown that Mavacamten can improve exercise capacity, alleviate symptoms (like chest pain and shortness of breath), and reduce the thickness of the heart muscle in patients with oHCM.

Administration: It's an oral medication, meaning it's taken by mouth.

Approval: As of my last update in January 2022, Mavacamten had received approval from the U.S. Food and Drug Administration (FDA) for the treatment of oHCM.

Safety and Side Effects: Like all medications, Mavacamten can have side effects. It's essential for patients to discuss potential risks and benefits with their healthcare provider.

It's worth noting that medical knowledge and drug approvals can evolve, so it's always a good idea to consult with a healthcare professional or check the latest resources for the most up-to-date information.
Camzyos: Take Two! Part 6
Camzyos: Take Two! Part 6 Side Effects 1 Views • 13 days ago

Good news from the doctor, some bad German, and hopefully better days ahead!
Camzyos Commercial (2024 & 2025, *Updated)
Camzyos Commercial (2024 & 2025, *Updated) Side Effects 0 Views • 13 days ago

*This is the same commercial from a year ago but with the FDA new rules on TV drug commercials in 2024 and it'll be on full effect on November 20th, 2024: all side effects on screen.

Original commercial before the new rules:
https://youtu.be/nKHfYoF85y0

New Treatment Option for Hypertrophic Cardiomyopathy | Mavacamten
New Treatment Option for Hypertrophic Cardiomyopathy | Mavacamten Side Effects 1 Views • 13 days ago

Mavacamten is a breakthrough therapy option for hypertrophic cardiomyopathy, a condition where the heart muscle becomes thick and stiff, making it harder for the heart to pump blood effectively. Mavacamten works by targeting the underlying cause of the disease, reducing the excessive contraction of heart muscle cells. This results in improved heart function and symptoms such as shortness of breath and fatigue. Mavacamten is a promising new option for patients with hypertrophic cardiomyopathy, providing hope for improved quality of life and long-term outcomes. Here Prof. Barlis introduces this therapy and provides some important updates on this condition and medication.
My Camzyos Journey - Part 5 - Month Two
My Camzyos Journey - Part 5 - Month Two Side Effects 1 Views • 13 days ago

Hello! Here's part five of my Camzyos journey. This is two months into being on this medicine? No news is good news? Stay tuned for updates! Feel free to reach out.
My Camzyos Journey: Part 8
My Camzyos Journey: Part 8 Side Effects 1 Views • 13 days ago

Got bumped up to 15 mg of Camzyos in March. Hear about how I'm doing! Feel free to reach out to me for questions, comments, or concerns.
Check in with Mike | See CAMZYOS PI at bit.ly/CAMZYOSpi
Check in with Mike | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 0 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://www.camzyos.com.

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at https://www.camzyos.com or click the icard in the video.

Mike has always been an active person, but everything changed when he started noticing that he was frequently short of breath and that he didn’t have the energy to do the things he loved. Mike found himself staying behind. In 2022, he was shopping at the store when he started feeling abnormally short of breath and pain in his heart. After taking multiple tests and talking with his cardiologist, he was diagnosed with symptomatic obstructive HCM and was eventually prescribed CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://www.camzyos.com.

Meet Kim | See CAMZYOS PI at bit.ly/CAMZYOSpi
Meet Kim | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 2 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://www.camzyos.com.

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at https://www.camzyos.com or click the icard in the video.

Kim was always a very active person. She was into sports and dance, and she loved playing softball. But she started to notice symptoms that forced her to adjust her lifestyle. Palpitations, chest pain, and tiredness—symptoms she initially dismissed as anxiety or depression—sidelined her from her favorite activities. It wasn’t until years later, at a routine checkup, when she had an irregular echocardiogram and was referred to a cardiologist who diagnosed her with symptomatic obstructive HCM. When her symptoms advanced to the point where she became eligible for SRT, she asked her cardiologist about CAMZYOS. Together, they decided it was the right option for her.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://www.camzyos.com.

How CAMZYOS Works | See CAMZYOS PI at bit.ly/CAMZYOSpi
How CAMZYOS Works | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 1 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.

Patients were compensated for their time.

Learn more about CAMZYOS at https://www.camzyos.com.

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at https://www.camzyos.com or click the icard in the video.

Learn how CAMZYOS, a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM) works to target at the source deep within the heart muscle.

Now that you’ve learned how CAMZYOS works, visit https://www.camzyos.com to learn more about CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://www.camzyos.com.

My Camzyos Journey: Part 7
My Camzyos Journey: Part 7 Side Effects 1 Views • 13 days ago

Part 7 of my Camzyos journey. I was bumped up from 5 mg to 10 mg, and then to 15 mg. Let's hope it does the trick! Any other diabetic or PA Dutch families out there? How has HCM affected you? Let me know!

0:10 Welcome!
1:35 Diabetes and HCM
1:59 Affected Populations
2:56 Taking my Dose (Almost Dying)
4:22 Shoutouts (and Suggestions for BMS)
Meet Barbara | See CAMZYOS PI at bit.ly/CAMZYOSpi
Meet Barbara | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 1 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://www.camzyos.com.

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid
weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at https://www.camzyos.com or click the icard in the video.

Barbara, who was told as a child she had a heart murmur, was used to living with symptoms such as occasionally becoming out of breath or feeling faint on a very hot day. This was her “normal,” so it didn’t occur to her to see a doctor about it. But one day when she was being prescreened for unrelated back surgery, she was diagnosed with symptomatic obstructive HCM. Barbara was put on a beta blocker at first, but her symptoms were still not improving. She was told that she would be a candidate for surgery, but by advocating for herself, she learned about a clinical trial. She was eligible to enroll, and after completion she learned she was receiving CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://www.camzyos.com.

Meet Stephanie | See CAMZYOS PI at bit.ly/CAMZYOSpi
Meet Stephanie | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 1 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://[a]www.camzyos.com.[/a]

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at www.camzyos.com or click the icard in the video.

Stephanie was a marathon runner who had to give up running and gradually lowered her level of activity over the years. She was recently diagnosed with symptomatic obstructive HCM/HOCM after her symptoms of shortness of breath and heart palpitations worsened. On the day she was diagnosed her cardiologist mentioned surgical options for her HCM. As her own advocate, she met with another cardiologist who prescribed CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://[a]www.camzyos.com.[/a]

What Happens To Your Body During an Overdose?
What Happens To Your Body During an Overdose? Side Effects 0 Views • 13 days ago

If we ever experience an opioid overdose, does it always mean the end? What is happening inside our bodies?
Check out Hollywood Health & Society: https://hollywoodhealthandsociety.org/

Support the great work being done by Lifespan, the team powering Life Noggin: https://www.lifespan.io/life-noggin/

Free resources: https://www.narcan.com/static/....NARCAN-Quick-Start-G
https://www.cdc.gov/drugoverdo....se/pdf/patients/prev
http://www.nchrc.org/programs-....and-services/naloxon
https://www.opensocietyfoundat....ions.org/publication
https://mountsinai.app.box.com..../s/s4tzf6fv3vwo1v98u
https://www1.nyc.gov/assets/do....h/downloads/pdf/basa
https://www.narcan.com/patients/how-to-use-narcan/
Other forms of administering Naloxone: https://www.drugpolicy.org/issues/naloxone
https://www.changingthenarrati....ve.news/naloxone-res
https://www.changingthenarrative.news/naloxone

Meet The Team!
Director/Voice - Pat Graziosi: http://twitter.com/PatGraziosi
Executive Producer - Ian Dokie: http://instagram.com/iandokie
Editor-In-Chief: Kaylee Yuhas
Animation by Steven Lawson
Written by Michael Sago

Sources for this Life Noggin video:
https://www.cdc.gov/drugoverdo....se/data/statedeaths.
https://hollywoodhealthandsociety.org/sites/default/files/attachments/page/Opioid%20epidemic_rev061319.pdf
https://www.hhs.gov/opioids/prevention/index.html
https://www.britannica.com/plant/opium-poppy
https://americanaddictioncenters.org/overdose
https://www.banyantreatmentcen....ter.com/2018/01/10/s
https://www.narcan.com/patients/how-to-use-narcan/
https://www1.nyc.gov/assets/do....h/downloads/pdf/basa
https://www.drugpolicy.org/issues/naloxone
https://www.cdc.gov/mmwr/previ....ew/mmwrhtml/mm6423a2
https://www.cdc.gov/drugoverdo....se/pdf/patients/prev

The EXPLORER-HCM study: mavacamten for obstructive HCM
The EXPLORER-HCM study: mavacamten for obstructive HCM Side Effects 1 Views • 13 days ago

This video summarizes the underlying cause of hypertrophic cardiomyopathy (HCM), common symptoms of HCM, mechanism of action of mavacamten, and key results of the EXPLORER-HCM trial, which compared mavacamten to placebo in patients with obstructive HCM.

Subscribe: https://www.youtube.com/channel/UCuVl...
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Watch here: https://www.biomedicine.video/animated-videos/the-explorer-hcm-study

#HCM #Cardiomyopathy #Mavacamten #EXPLORER

Check in with Dani | See CAMZYOS PI at bit.ly/CAMZYOSpi
Check in with Dani | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 0 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://[a]www.camzyos.com.[/a]

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at www.camzyos.com or click the icard in the video.

Dani has had a long journey with obstructive HCM/HOCM. It took quite a while to discover the root of the problem and receive an obstructive HCM diagnosis. She started to feel her symptoms improving after undergoing open-heart surgery, but then her obstruction came back, so she began looking for another option. Then, Dani and her doctor decided to try CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://[a]www.camzyos.com.[/a]

Meet Dani | See CAMZYOS PI at bit.ly/CAMZYOSpi
Meet Dani | See CAMZYOS PI at bit.ly/CAMZYOSpi Side Effects 1 Views • 13 days ago

Please see Important Safety Information, including Boxed WARNING, and U.S. Full Prescribing Information at https://bit.ly/CAMZYOSpi and Medication Guide at https://bit.ly/CAMZYOSMedGuide.
Patients were compensated for their time.
Learn more about CAMZYOS at https://www.camzyos.com.

CAMZYOS® (mavacamten) is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM). CAMZYOS may improve your symptoms and your ability to be active. It is not known if CAMZYOS is safe and effective in children.

WARNING: RISK OF HEART FAILURE

CAMZYOS may cause serious side effects, including:
Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms before you take your first dose and during your treatment with CAMZYOS to help your healthcare provider understand how your heart is responding to CAMZYOS. People who develop a serious infection or irregular heartbeat have a greater risk of heart failure during treatment with CAMZYOS. Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, swelling in your legs, a racing sensation in your heart (palpitations), or rapid weight gain.

The risk of heart failure is also increased when CAMZYOS is taken with certain other medicines. Tell your healthcare provider about the medicines you take, both prescribed and obtained over-the-counter, before and during treatment with CAMZYOS.

Because of the serious risk of heart failure, CAMZYOS is only available through a restricted program called the CAMZYOS Risk Evaluation and Mitigation Strategy (REMS) Program. Before you take CAMZYOS, you must enroll in the CAMZYOS REMS Program.

See full ISI at https://www.camzyos.com or click the icard in the video.

Dani was diagnosed with obstructive HCM (oHCM) in her 50s. It started with symptoms like shortness of breath or fatigue while doing simple things like shopping or walking. When she was diagnosed, Dani tried an oral medication, but her obstruction didn’t improve and she eventually needed a myectomy, a type of open heart surgery. Despite this, and having tried a few other treatment options, her symptoms did not improve. Then, her doctor prescribed CAMZYOS.

For additional Important Safety Information, U.S. Full Prescribing Information, including Boxed WARNING, visit https://bit.ly/CAMZYOSpi.

Learn more about CAMZYOS at https://www.camzyos.com.

MedTap: Mavacamten side effects
MedTap: Mavacamten side effects Side Effects 1 Views • 13 days ago

Mavacameten is a medication used in the treatment of hypertrophic cardiomyopathy. This video explains what it is and how it works, and some of the common side-effects you need to be aware of.
Mavacamten (Camzyos) for Hypertrophic cardiomyopathy
Mavacamten (Camzyos) for Hypertrophic cardiomyopathy Side Effects 2 Views • 13 days ago

Mavacamten, marketed under the brand name Camzyos, is a medication specifically approved for the treatment of hypertrophic cardiomyopathy (HCM), particularly obstructive HCM. This is a genetic condition characterized by the thickening of the heart muscle, which can lead to obstruction of blood flow and various symptoms such as shortness of breath, chest pain, and fatigue.

How Mavacamten Works
Mavacamten is a first-in-class cardiac myosin inhibitor.

Targeting Myosin: Myosin is a motor protein in heart muscle cells responsible for contraction. In HCM, there is an excessive interaction between myosin and actin (another protein), leading to hypercontractility and thickening of the heart muscle.

Mechanism of Action: Mavacamten works by selectively inhibiting cardiac myosin. This reduces the excessive contractility of the heart muscle, helps relax the muscle, and reduces the obstruction in the left ventricular outflow tract (LVOT). As a result, blood flow from the heart is improved, and symptoms are alleviated.

Indication and Use
Mavacamten is approved for the treatment of symptomatic obstructive hypertrophic cardiomyopathy in adults.

Symptomatic Obstructive HCM: This form of HCM involves a thickened heart muscle that obstructs blood flow out of the heart, leading to symptoms like shortness of breath, chest pain, and fainting. Mavacamten is particularly beneficial for patients who remain symptomatic despite other treatments, such as beta-blockers or calcium channel blockers.

Benefits
Mavacamten offers several important benefits for patients with obstructive HCM:

Reduction in Symptoms: Clinical trials have shown that mavacamten significantly reduces symptoms associated with obstructive HCM, such as shortness of breath, chest pain, and exercise intolerance.

Improved Exercise Capacity: Patients treated with mavacamten have demonstrated improved exercise capacity, as measured by cardiopulmonary exercise testing (CPET). This improvement in exercise tolerance is a significant benefit for patients with HCM, who often experience limitations in physical activity.

Reduction in LVOT Gradient: Mavacamten effectively reduces the LVOT gradient, which is the pressure difference caused by the obstruction in blood flow. Lowering this gradient helps to alleviate symptoms and improve heart function.

Potential to Avoid Surgery: For some patients, mavacamten may reduce the need for invasive procedures, such as septal myectomy (surgical removal of part of the thickened heart muscle) or alcohol septal ablation.

Side Effects
While mavacamten is generally well-tolerated, it can cause side effects, particularly related to its impact on heart function:

Heart Failure: Because mavacamten reduces heart contractility, there is a risk of heart failure if the dose is too high. This necessitates careful monitoring of heart function, particularly ejection fraction (a measure of how well the heart is pumping blood).

Arrhythmias: There is a potential risk for arrhythmias (irregular heartbeats), which also requires monitoring.

Other Side Effects: Some patients may experience symptoms like dizziness, fainting, and fatigue.

Drug Interactions: Mavacamten can interact with other medications, especially those metabolized by the liver enzyme CYP2C19. This necessitates caution when prescribing mavacamten alongside other drugs.

Human Impact
Hypertrophic cardiomyopathy is a condition that can significantly impact a person's quality of life, leading to symptoms that interfere with daily activities and increase the risk of serious complications, including sudden cardiac death. Traditional treatments focus on managing symptoms and reducing the risk of complications, but they do not directly address the underlying hypercontractility of the heart muscle.

Mavacamten (Camzyos) represents a groundbreaking treatment for obstructive HCM because it directly targets the excessive contractility of the heart muscle, offering a novel mechanism of action compared to traditional therapies. For patients with symptomatic obstructive HCM, mavacamten provides a new option that can reduce symptoms, improve quality of life, and potentially decrease the need for surgical interventions.

The development of mavacamten is a significant milestone in the management of hypertrophic cardiomyopathy, providing hope for improved outcomes in a condition that has been difficult to manage with existing therapies. By addressing the root cause of the obstruction, mavacamten offers a targeted and effective treatment that can help patients with HCM live more active and comfortable lives.
Drug Reduces the Need for Surgery in Nearly 90% of Patients with HCM, Cleveland Clinic Study Shows
Drug Reduces the Need for Surgery in Nearly 90% of Patients with HCM, Cleveland Clinic Study Shows Side Effects 3 Views • 13 days ago

To read more about the VALOR-HCM study, please visit https://cle.clinic/3ti8ExY

Findings from a Cleveland Clinic-led clinical trial, the VALOR-HCM study, showed that the use of mavacamten in severely symptomatic, hypertrophic cardiomyopathy patients significantly reduced the need for invasive procedures.

To learn more about Dr. Milind Desai, please visit https://cle.clinic/2XvWi51

If you liked the video hit like and subscribe for more!
#clevelandclinic #consultqd #valorhcm

Camzyos capsules how to use: Uses, Dosage, Side Effects, Contraindications
Camzyos capsules how to use: Uses, Dosage, Side Effects, Contraindications Side Effects 2 Views • 13 days ago

Camzyos is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM).
Camzyos may improve your symptoms and your ability to be active.

Video Content:
0:00 Camzyos capsules
0:17 How to use
1:04 Contraindications
1:32 Warnings
2:20 Side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Camzyos #hcm #medicine
Camzyos: Unlisted Side Effects
Camzyos: Unlisted Side Effects Side Effects 0 Views • 13 days ago

Recap! All the news about my beta blockers, calcium channel blockers, Camzyos changes, and some very common but unlisted side effects. Are you experiencing any of these?
CALQUENCE® (acalabrutinib) Perspectives: Dr Alexey Danilov, MD, PhD
CALQUENCE® (acalabrutinib) Perspectives: Dr Alexey Danilov, MD, PhD Side Effects 1 Views • 13 days ago

Please see full Prescribing Information: https://qr.short.az/CalquenceUSPI
This video is intended for US healthcare professionals only.

Dr. Danilov discusses CALQUENCE in preclinical assays and ELEVATE-TN data.

Topics include mechanism of disease (MOD), CALQUENCE® (acalabrutinib) selectivity, and patients with high-risk cytogenetics.

Indications and Select Safety Information
CALQUENCE is indicated in combination with bendamustine and rituximab (BR) for the treatment of adult patients with previously untreated mantle cell lymphoma (MCL) who are ineligible for autologous hematopoietic stem cell transplantation (HSCT), as monotherapy for the treatment of adult patients with MCL who have received at least one prior therapy, and for the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Serious adverse events, including fatal events, have occurred with CALQUENCE, including serious and opportunistic infections, hemorrhage, cytopenias, second primary malignancies, cardiac arrhythmias, and hepatotoxicity, including drug-induced liver injury. The most common adverse reactions (≥30%) are diarrhea, upper respiratory tract infection, headache, musculoskeletal pain, lower respiratory tract infection, and fatigue. The most common Grade 3 or 4 laboratory abnormalities (≥10%) are absolute neutrophil count decreased, absolute lymphocyte count decreased, platelets decreased, and hemoglobin decreased.

Calcent Capsule: Acalabrutinib: Uses, Dosage, Side Effects, Warnings
Calcent Capsule: Acalabrutinib: Uses, Dosage, Side Effects, Warnings Side Effects 0 Views • 13 days ago

Calcent Capsule: Acalabrutinib mechanism of action is by blocking BT this helps to stop cancer cells rom growing and multiplying, to help reduce cancer growth.
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ACALABRUTINIB, What is acalabrutinib used for, Acalabrutinib CALQUENCE review
ACALABRUTINIB, What is acalabrutinib used for, Acalabrutinib CALQUENCE review Side Effects 1 Views • 13 days ago

What is Acalabrutinib? and What is Acalabrutinib used for?

Brand name of acalabrutinib is Calquence.
Acalabrutinib is used to treat people with mantle cell lymphoma (MCL; a fast-growing cancer that begins in the cells of the immune system) who have already been treated with at least one other chemotherapy medication.
It is also used alone or with obinutuzumab (Gazyva) to treat chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells) and small lymphocytic lymphoma (SLL: a type of cancer that begins in the white blood cells).
Acalabrutinib is in a class of medications called kinase inhibitors.
It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.


How to use Acalabrutinib?


Acalabrutinib comes as a capsule to take by mouth. It is usually taken with or without food every 12 hours (twice a day) for as long as your doctor recommends that you receive treatment.
Take acalabrutinib at around the same times every day.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take acalabrutinib exactly as directed.
Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the capsules whole with a glass of water; do not open, chew, or break them.

Your doctor may temporarily or permanently stop your treatment or decrease your dose of acalabrutinib depending on the side effects that you experience. Be sure to talk to your doctor about how you are feeling during your treatment. Do not stop taking acalabrutinib without talking to your doctor.


Whaen to take Acalabrutinib?

Before taking acalabrutinib,

tell your doctor and pharmacist if you are allergic to acalabrutinib, any other medications, or any of the ingredients in acalabrutinib capsules.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.

if you are taking cimetidine (Tagamet), famotidine (Pepcid, in Duexis), nizatidine (Axid), or ranitidine (Zantac) take acalabrutinib at least 2 hours before taking these medications.

if you are taking antacids (Maalox, Mylanta, Tums, others) take acalabrutinib at least 2 hours before or after taking these medications.

tell your doctor if you have an infection or have had surgery recently, or if you have or have ever had liver disease including hepatitis B, problems with your heart rhythm, or bleeding problems.

tell your doctor if you are pregnant or plan to become pregnant.
You should not become pregnant while you are taking acalabrutinib.
You should not start taking acalabrutinib until a pregnancy test has shown that you are not pregnant and you should use birth control to prevent pregnancy during your treatment and for at least 1 week after your final dose.
Acalabrutinib may harm your unborn baby. If you become pregnant while taking acalabrutinib, call your doctor immediately.

tell your doctor if you are breastfeeding. Your doctor may tell you not to breastfeed during your treatment and for 2 weeks after your final dose.

if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking acalabrutinib.
Your doctor may tell you to stop taking acalabrutinib for a period of time before and after the surgery or procedure.

plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen.
Acalabrutinib may make your skin sensitive to the dangerous effects of the sunlight, and may increase your risk of developing skin cancer.


What side effects can Acalabrutinib cause?


Acalabrutinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

headache.
nausea.
vomiting.
constipation.
diarrhea.
abdominal pain.
rash.
light bruising or small red or purple spots on skin.
joint or muscle pain.
extreme tiredness.
CALQUENCE® (acalabrutinib) Perspectives: Dr Tara Graff, DO
CALQUENCE® (acalabrutinib) Perspectives: Dr Tara Graff, DO Side Effects 1 Views • 13 days ago

Please see full Prescribing Information: https://qr.short.az/CalquenceUSPI
This video is intended for US healthcare professionals only.

Dr Graff shares three reasons to consider CALQUENCE® (acalabrutinib) for adult patients with chronic lymphocytic leukemia (CLL).

Indication and Select Safety Information
CALQUENCE is indicated for the treatment of adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).
Serious adverse events, including fatal events, have occurred with CALQUENCE, including serious and opportunistic infections, hemorrhage, cytopenias, second primary malignancies, cardiac arrhythmias, and hepatotoxicity, including drug-induced liver injury. The most common adverse reactions (≥30%) are diarrhea, upper respiratory tract infection, headache, musculoskeletal pain, lower respiratory tract infection, and fatigue. The most common Grade 3 or 4 laboratory abnormalities (≥10%) are absolute neutrophil count decreased, absolute lymphocyte count decreased, platelets decreased, and hemoglobin decreased.

Wendy’s Patient Testimonial Video
Wendy’s Patient Testimonial Video Side Effects 0 Views • 13 days ago

Please see Full Prescribing Information, including Patient Information, for CALQUENCE® (acalabrutinib): https://qr.short.az/CalquenceUSPI.

This video is intended for US audiences only.

When Wendy was diagnosed with CLL in 2020, she was expecting the worst and hoping for the best. Hear how she overcame her fear, navigated treatment, and found support.

*IMPORTANT PRODUCT INFORMATION*
CALQUENCE is a prescription oral treatment for adults with chronic lymphocytic leukemia or small lymphocytic lymphoma. Can cause serious side effects including: serious infections, bleeding problems, decrease in blood cell count, new cancers, heart rhythm problems, and liver problems. Some may lead to death. Tell your doctor if you experience infections such as flu-like symptoms; unexpected bleeding such as blood in your stool or urine; heart rhythm problems such as fast or irregular heartbeat; or liver problems such as stomach pain, dark urine or yellowing of your skin. Use sun protection when outside.

CALQUENCE - Generic Name, Brand Names, How to use, Precautions, Side Effects
CALQUENCE - Generic Name, Brand Names, How to use, Precautions, Side Effects Side Effects 1 Views • 13 days ago

#medicalknowledgeonline
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Steve’s Patient Testimonial Video
Steve’s Patient Testimonial Video Side Effects 0 Views • 13 days ago

Please see Full Prescribing Information, including Patient Information, for CALQUENCE® (acalabrutinib): https://qr.short.az/CalquenceUSPI.

This video is intended for US audiences only.

Steve shares his CLL story, how he manages treatment, and why a positive attitude can help throughout the patient journey.

*IMPORTANT PRODUCT INFORMATION*
CALQUENCE is a prescription oral treatment for adults with chronic lymphocytic leukemia or small lymphocytic lymphoma. Can cause serious side effects including: serious infections, bleeding problems, decrease in blood cell count, new cancers, heart rhythm problems, and liver problems. Some may lead to death. Tell your doctor if you experience infections such as flu-like symptoms; unexpected bleeding such as blood in your stool or urine; heart rhythm problems such as fast or irregular heartbeat; or liver problems such as stomach pain, dark urine or yellowing of your skin. Use sun protection when outside.

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