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Hydralazine (Apresoline) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings Side Effects 3 Views • 5 months ago

Hydralazine (Apresoline) – Uses, Side Effects, Mechanism of Action, Dosage, Interactions, Warnings
Hydralazine, sold under the brand name Apresoline, is a direct-acting vasodilator primarily used to treat moderate to severe hypertension, including hypertensive crises, and to manage chronic heart failure—especially in patients intolerant to ACE inhibitors or ARBs. It is also considered relatively safe for controlling high blood pressure during pregnancy, such as in pre-eclampsia and eclampsia. Hydralazine works by relaxing arteriolar smooth muscle, reducing systemic vascular resistance and afterload, although it may cause reflex tachycardia due to sympathetic stimulation. Oral dosing typically starts at 10 mg four times daily, with maintenance doses ranging up to 100 mg four times daily; intravenous administration is reserved for acute settings. Common side effects include headache, dizziness, palpitations, and flushing, while serious effects may include drug-induced lupus, peripheral neuropathy, and myocardial infarction. It interacts with various drugs such as beta-blockers, NSAIDs, MAO inhibitors, and other antihypertensives. Caution is advised in patients with ischemic heart disease or renal impairment, and monitoring is essential during prolonged use.
#hydralazine #apresoline #hydralazineuses #apresolineuses #hydralazinesideeffects #apresolinesideeffects #htn
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Humira: The Most Financially Successful Drug Ever! Side Effects 2 Views • 5 months ago

Humira: The Most Financially Successful Drug Ever!

Humira has made $200 Billion over the course of its pharmaceutical life. The original Humira patent expired, but the makers of Humira--AbbVie--filed an additional 132 patents and extended its patent-life to 2023.

During that time, AbbVie raised the price of Humira 30 times from $522 per syringe to $2,984 per syringe. It now costs $78,000 per year to treat one patient with Humira.

Consequently, AbbVie rose to be worth $270 Billion and is the 23rd most valuable company on the stock market... $80 Billion larger than the Walt Disney Company.

Express Scripts, Optum and Prime Therapeutics will offer biologic alternatives to Humira in 2023, but CVS Caremark has yet to announce any alternative to the expensive medication.

Humira shows how completely ineffective PBMs are in controlling specialty pharmacy costs.

Alternative solutions include: 1) Travel to Mexico/Canada to buy specialty drugs for less, 2) Hire own specialists (e.g. rheumatologists) who will be better stewards of the employers resources while still following clinical best-practices, 3) Have lawyers try to get plan members that take specialty medications on Disability so that Medicare will cover their medication costs, 4) Legislative Advocacy to counter the Pharma lobbying that allowed for confiscatory pricing of specialty pharmacy medications.

Sources:
https://www.fiercepharma.com/s....pecial-reports/top-1

https://news.bloomberglaw.com/....ip-law/abbvies-humir

https://www.fiercehealthcare.c....om/payers/express-sc

https://www.prnewswire.com/new....s-releases/prime-the

https://www.bloomberg.com/news..../articles/2023-01-06

https://www.biopharmadive.com/....news/humira-abbvie-b

https://clincalc.com/DrugStats/Drugs/Adalimumab

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Understanding Humira: What You Need to Know Side Effects 2 Views • 5 months ago

If you or a loved one are exploring the world of Humira, this video is a vital resource to help you understand what this medication is all about.

Unveiling Humira:
In this video, we demystify Humira, a groundbreaking biologic drug that's transforming the lives of those battling chronic conditions linked to the immune system. Discover the key facts you should be aware of to make informed decisions about your health.

The Mechanism Behind Humira:
Learn how Humira works its magic by targeting TNF (tumor necrosis factor), a critical protein in your body associated with inflammation. Understanding this mechanism is pivotal to grasp how Humira can bring relief to those affected by certain health conditions.

Taking Humira with Confidence:
Are you apprehensive about self-administering Humira? Fear not! We'll guide you through the process and shed light on how it's done, ensuring you can take this step with confidence.

Potential Side Effects:
As with any medication, Humira may have side effects. We'll delve into these, detailing the most common ones such as injection site discomfort, headaches, increased susceptibility to respiratory infections, and occasional nausea or stomach discomfort. Being informed empowers you to navigate your health journey.

Consult Your Healthcare Provider:
Before embarking on the Humira journey, remember that consulting your healthcare provider is non-negotiable. Your doctor's expertise is indispensable in determining whether Humira is the right treatment for your unique condition and providing guidance on its safe usage.

In Conclusion:
Humira is a potent ally in managing chronic conditions, but it's vital to be well-informed and maintain open communication with your healthcare provider. Your well-being is paramount, and we're here to support you every step of the way.

If you found this video helpful and enlightening, be sure to show your appreciation by giving it a thumbs up. Subscribe for more insightful content on healthcare and well-being. Thank you for watching, and may you embark on your health journey with confidence and knowledge. Stay healthy!

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The Humira Alternative for Inflammation – Dr. Berg On Rheumatoid Arthritis Symptoms Side Effects 2 Views • 5 months ago

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In this video, Dr. Berg talks about the Humira alternative. Humira is an anti-inflammatory blockbuster and a top-selling prescription drug.

In the US, 70% of the population is on at least 1 drug. Glucose is highly inflammatory and a potent trigger for inflammation. Insulin is anti-inflammatory but high levels of insulin in the blood are also inflammatory.

Consuming too much glucose, sugar, and carbs will increase insulin and develop into a condition called insulin resistance. Lowering insulin resistance could lower inflammation as well.

Ways to Drop Inflammation:
• Low Carb Diet or Healthy Ketosis
• Intermittent Fasting

Dr. Eric Berg DC Bio:
Dr. Berg, age 56, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

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Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

#keto #ketodiet #weightloss #ketosis

Humira Side Effects (These Two Can Trick Your Doctor Into Thinking Something Else Is Wrong) Side Effects 1 Views • 5 months ago

11 Natural Therapies (Outside of Drugs And Surgery) That Actually Work [free checklist]: https://curtis-alexander.com/

Humira (adalimumab) is one of the newer and more popular injectable medications on the market. You can use it to treat everything from arthritis, psoriasis to digestive issues like Crohn's and Ulcerative Colitis.

It works in your body by blocking a compound that's involved with inflammation.

Like I've explained before inflammation could be both good and bad. Good in that it's one of the first steps in your immune response but bad when it gets out of hand like it can with arthritis, Crohn's and Ulcerative Colitis.

So when you block a natural inflammatory process you can get side effects associated with that inflammatory process.

Most Common Side Effects of Humira

1) Infection (especially in kids - up to 46%) - Like I mentioned above inflammation is one of the first steps in a natural inflammatory process and as part of the your immune response so when you block this you're essentially lowering your immune system which can lead to more infections.

I did want to point out that infections can happen to everybody but appears to be more problematic in kids who are given Humira.

2) Antibody Development (3%-26%) - anytime you inject something like Humira into your system your body can develop antibodies to it. In extreme cases it can develop neutralizing antibodies. When this happens the drug will become ineffective.

This is one of the reasons why you can see injectable drugs lose their effectiveness over time.

3) Injection Site Reactions (5%-20%) - these types of reactions are fairly common but not all that problematic and most people. Usually what you'll see is some redness and swelling around the area of injection.

4) Elevated CPK (Creatine Phosphokinase) (15%) - This is an enzyme that she'll see in the heart, muscle and the Brain. When you see elevations it's usually a sign of some sort of damage in those areas. So it's important that your doctor know you're on Humira so she doesn't think something is wrong.

5) Positive ANA Titer (12%) - high Anti-nuclear antibodies (ANA) is something you usually see in people with lupus. Again, that's why it's important for your doctor to know that you're taking Humira and why you may have a false increase in your ANA titer.

What About Weight Loss and Weight Gain?

Humira can cause some nausea in up to 9% of users. So if there's going to be anything you're more likely to see weight loss because people can lose a little bit of their appetite.

What About Hair Loss?

Hair loss isn't anything that was mentioned in any of the studies that I saw. Furthermore, I haven't had any people who buy used to Humira report hair loss to me.

I will point out though that some users across the country have reported that in rare cases but again I want to stress that it's rare and unlikely.

Humira /adalimumab for Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis Side Effects 1 Views • 5 months ago

Adalimumab (Humira) is one of the most common biologic medications that we use for patients suffering from inflammatory arthritis, like rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis. Learn all you need to know about this medication.

#humira #rheumatoidarthritis #psoriaticarthritis

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Chapters
0:00 Intro
2:11 ---What is Adalimumab/ Humira?
2:55 ---What is the effect of Humira in arthritis patients?
3:47 ---Is Humira a pill or an injectable medication?
4:44 ---What #tests are needed before starting therapy?
5:33 ---Can Humira be combined with other #medications such as biologics?
6:08 ---What are the most common #effects ?
6:57 ---Can Humira increase the risk of #infections and how common are the SEVERE infections?
7:56 ---How can you prevent certain infections?
8:18 ---What #vaccines are recommended before starting therapy?
8:31 ---Can Humira increase the risk of #cancer?
9:13 ---Is Humira safe for patients with #heart failure?
9:41 ---Is Humira safe for #pregnancy?
10:23 Closing

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Humira I 12 Important Facts About Humira in Arthritis You Need To Know | Dr. Diana Girnita
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Dr. Girnita teaches patients about autoimmune disease, arthritis and also helps them customized their treatment plans. Dr. Girnita is passionate about rheumatoid arthritis. The treatment plan is personalized to the patients needs and incorporates the proper nutrition, exercise and management of stress. After all,
"You have a disease, but YOU are not the disease"

** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a medical consultation. Any comments and/or recommendations made in the comment section by anyone other than Rheumatologist OnCall does not reflect our opinion or recommendation.**

Humira | Adalimumab – Uses, Side Effects, Dosage, Warnings Side Effects 2 Views • 5 months ago

Humira | Adalimumab – Uses, Side Effects, Dosage, Warnings
Adalimumab, commonly known by its brand name Humira, is a medication that belongs to a class of drugs called tumor necrosis factor (TNF) inhibitors. It is primarily used to treat various inflammatory and autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis.
In this video, we'll have a look at the uses and side effects of Humira (Adalimumab).
#humira #adalimumab #tumornecrosisfactorinhibitors #TNF #Adalimumabsideeffects #humirasideeffects
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Chlorhexidine Best mouth wash for bad smell . Use dose or side effects in hindi #chlorhexidin Side Effects 4 Views • 5 months ago

chlorhexidine Best mouth wash for bad smell . Use dose or side effects in hindi #chlorhexidine
#mouthwash
#medicine #treatmentinindia

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