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Dexlansoprazole 30 mg (Dexilant): What is Dexlansoprazole? Dexilant Uses, Dose, Side Effects Side Effects 2 Views • 5 months ago

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- This is lesson n# 116 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Dexlansoprazole 30 mg (Dexilant): What is Dexlansoprazole? Dexilant Uses, Dose, Side Effects, Precautions and Mechanism of Action

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- In 2 minutes you'll learn about:

- What is Dexlansoprazole 30 mg (Dexilant)?

- Dexlansoprazole belongs to a category of medication called proton pump inhibitors, it suppresses the secretion of gastric acid, by combining with an enzyme located on the gastric parietal cells, called hydrogen potassium ATPase, which is the final pathway for acid secretion. And this decreases hydrogen ion transport into gastric lumen, leading to reduction of the secretion of gastric acid.

- Dexlansoprazole is available as 30 mg and 60 mg delayed-release capsules.

- It is used in the treatment of heartburn caused by gastroesophageal reflux disease (GERD), and to heal erosive esophagitis (damage to the esophagus from stomach acid).

- Learn more about Dexlansoprazole 30 mg (Dexilant) mechanism of action, uses, dosage, side effects, and precautions in this video...

- Video Chapters:
00:12 - Dexlansoprazole Mechanism of Action
00:37 - Dexlansoprazole Dosage Forms
00:45 - Dexlansoprazole Uses
00:55 - Dexlansoprazole Dosage (Dexilant dose)
01:19 - Dexlansoprazole Side Effects
01:25 - Dexlansoprazole Precautions

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#icutalk 3: Corticosteriods in ICU (Hydrocortisone, Methylprednisolone, Dexamethasone); Difference? Side Effects 2 Views • 5 months ago

*in the beginning of the video at 1.14 min, there is slip of tongue, it's adrenal gland NOT kidney from where corticosteroids are secreted.

Onset of action (missed in the video)
Hydrocortisone Onset of action: IV: 1 hour.
Methylprednisolone Onset of action: IV (succinate): Within 1 hour; Intra-articular (acetate): 1 week
Dexamethasone Onset of action: IV: Rapid.

Difference between various corticosteroids in ICU specifically Hydrocortisone, Methylprednisolone, Dexamethasone
#steroids_in_icu

This above video has tried to address and explain the following things:
Why we use difference steroids in icu,
difference between Hydrocortisone Methylprednisolone Dexamethasone,
when to use which corticosteroid in icu,
glucocorticoid and mineralocorticoid activity of corticosteroid,
duration of action of different corticosteroids,
orticosteroids explained in a simple way,

The ICU Channel is a project by Educational Society of Bedside Intensive Care Medicine (ESBICM) for providing forever free bedside intensive care education to doctors and nurses working in ICU & ED.
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We hope that this small effort of ours will be of help to healthcare professionals working in ICU and emergency department and ultimately will improve the care of critically ill patients. #theicuchannel

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Keep learning!
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Dexametasona ¿Cuándo y cómo debemos administrarla? Tu Farmacéutico Informa Side Effects 2 Views • 5 months ago

Videoconsejo sanitario sobre Dexametasona, cuándo y cómo debemos administrar este principio activo. Videoconsejo impartido por el farmacéutico Eduardo Ramírez, elaborado por el Consejo General de Colegios Farmacéuticos y producido por Medicina TV.

Dexametasona es un glucocorticoide altamente potente y de larga duración, con una intensa actividad antiinflamatoria y con propiedades antialérgicas, antipiréticas e inmunosupresoras.

Se encuentra disponible en forma de colirio en solución o suspensión, pomada oftálmica, gotas óticas, implante intravítreo, comprimidos, solución inyectable, bucal y laringofaríngea y gel oftálmico.

La concentración más habitual de los formatos vía oftálmica es de 1 mg/ml en colirios y gel y 0,5 mg/g en pomada. Para los comprimidos, existen comercializadas dosis de 1, 4, 8 y hasta 20 mg. En el caso de las soluciones inyectables la dosis más habitual es la de 4 mg/ml.

A nivel oftálmico, dexametasona en colirio se administra habitualmente con 1 gota de 3-6 veces al día, y en pomada de 2-3 veces al día.
o Dexametasona oftálmica está indicada para el tratamiento de las inflamaciones de la conjuntiva bulbar y palpebral, córnea, y enfermedades inflamatorias del segmento anterior del ojo. También para el tratamiento de lesiones de la córnea por cuerpo extraño, químicas o térmicas.
o Además, tiene indicación para tratar determinados tipos de queratitis y queratoconjuntivitis, y en el caso de inflamación postoperatoria ocular.

En el caso de los comprimidos, las dosis habituales son de 0,5 a 10 mg al día, dependiendo de la enfermedad que esté siendo tratada, las características individuales y usando la menor dosis efectiva posible.

Para la administración parenteral, se suelen administrar dosis iniciales relativamente altas, siendo mayores en las formas agudas graves que en las enfermedades crónicas.

Entre sus indicaciones en tratamientos sistémicos, se encuentran el tratamiento de procesos endocrinológicos como en la enfermedad de Addison, o para el tratamiento de procesos alérgicos graves resistentes a los tratamientos convencionales, como en el asma.

También para el tratamiento sistémico de brotes en la enfermedad de Crohn o la colitis ulcerosa.

A nivel dermatológico, se usa como tratamiento inicial de enfermedades graves, como la dermatitis exfoliativa o la psoriasis severa.

También se utiliza en algunos cuadros hematológicos por vía intravenosa, y como coadyuvante para el tratamiento de patologías reumáticas en cuadros agudos y exacerbaciones, como artritis o artrosis.

Mediante inyección local, está indicada en crisis agudas de epicondilitis, artritis gotosa, o lesiones de naturaleza inflamatoria e hipertrófica, como la psoriasis.

Debido a que atraviesa la barrera hematoencefálica, también cuenta con indicación para el tratamiento del edema cerebral secundario a determinadas patologías.

Recientemente, se ha autorizado el uso en el tratamiento de la COVID-19 en asociado a oxigenoterapia.

Dexametasona está contraindicado en pacientes que tengan una infección sistémica a, menos que se emplee un tratamiento antiinfeccioso específico, en la úlcera de estómago o úlcera duodenal y en vacunación con vacunas vivas.

En el caso de embarazo y lactancia, la decisión de prescribirla debe evaluarse cuidadosamente por el profesional sanitario, valorando beneficios y riesgos.

En la población pediátrica en tratamiento prolongado con dexametasona, habrá que monitorizar la tasa de crecimiento regularmente, ya que los corticosteroides pueden afectar al crecimiento.

Los efectos adversos dependen en mayor grado de la duración del tratamiento que de la dosis empleada.

Los más habituales son, a corto plazo, el aumento de peso, trastornos psicológicos, intolerancia a la glucosa e insuficiencia suprarrenal transitoria. Si el tratamiento se mantiene durante meses o años, puede provocar obesidad central, fragilidad de la piel, atrofia muscular, osteoporosis, retraso del crecimiento e insuficiencia suprarrenal.

Las dosis se deben reducir gradualmente para finalizar el tratamiento, por riesgo de síndrome de retirada o recurrencia de la enfermedad subyacente.

Y recuerda, pregunta siempre a tu farmacéutico de confianza. Te informaremos sobre los efectos y el modo de uso de dexametasona y sobre cualquier otra duda que tengas.

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Corticosteroid Side Effects (Mnemonic) - What are the side effects of corticosteroids? Side Effects 3 Views • 5 months ago

A mnemonic to help you remember what are the side effects of corticosteroids! This quick mnemonic is CORTICOSTEROIDS and is an easy way to remember the side effects of corticosteroids.

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Most Important Side Effects of Corticosteroids Side Effects 3 Views • 5 months ago

Corticosteroid Side Effects, How to reduce risk?
What side effects can corticosteroids cause?
Fluid retention, causing swelling in your lower legs.
High blood pressure.
Problems with mood swings, memory, behavior, and other psychological effects, such as confusion or delirium.
Upset stomach.

What are the side effects of corticosteroid drugs?
Potential side effects of long-term treatment include:
increased appetite – potentially leading to weight gain.
acne.
thinned skin that bruises easily.
increased risk of infections.
mood changes, mood swings and depression.
diabetes.
high blood pressure.
osteoporosis (weak and brittle bones)

What are the most common side effects of corticosteroids?
What are the possible side effects of steroids?
Increased appetite.
Weight gain.
Changes in mood.
Muscle weakness.
Blurred vision.
Increased growth of body hair.
Easy bruising.
Lower resistance to infection

What does corticosteroid do to the body?
Corticosteroids can reduce inflammation in the body and relieve related symptoms, such as body pain, swelling, and stiffness. Corticosteroids reduce inflammation by suppressing the immune system. They are a standard treatment for autoimmune conditions, which often cause inflammation in the body.

What are the side effects of long-term treatment with corticosteroids?
Long-term corticosteroid use may be associated with more serious sequel, including osteoporosis, aseptic joint necrosis, adrenal insufficiency, gastrointestinal, hepatic, and ophthalmologic effects, hyperlipidemia, growth suppression, and possible congenital malformations.

How long do steroids stay in your system?
How long will it be detectable? If taken orally, steroids can show up in a urine test for up to 14 days. If injected, steroids can show up for up to 1 month.

How long is long term steroid use?
Treatment extending longer than three months is considered long term and results in the majority of severe side effects. When steroids are used for short durations of a few days or weeks, they are relatively safe.

What drugs should not be taken with steroids?
You should tell any doctor or dentist treating you that you are taking steroids. Some key drugs that interact with steroids include anticoagulants (such as warfarin), drugs for blood pressure, antiepileptics, antidiabetic drugs, antifungal drugs, bronchodilators (such as salbutamol) and diuretics.

Are steroids the same as corticosteroids?
Corticosteroids are a form of steroids used to treat swelling and inflammation from allergies, as well as allergic asthma. They're often referred to as steroids, but they're not the same types of products abused by some athletes. Corticosteroids may be used for a range of allergies.
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Does your body go back to normal after prednisone?
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Can corticosteroids damage skin?
Topical corticosteroids, though very useful for treatment of dermatological disorders can produce various side effects. Some of these side effects may seriously damage the skin. Hence, topical corticosteroids should be used with utmost caution.
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Does Dexamethasone Cause Muscle Weakness? - Pain Medicine Network Side Effects 3 Views • 5 months ago

Does Dexamethasone Cause Muscle Weakness? In this informative video, we will address an important topic related to pain management: the potential side effects of dexamethasone, specifically focusing on muscle weakness. Dexamethasone is a commonly prescribed corticosteroid known for its effectiveness in reducing inflammation. However, like many medications, it may come with certain side effects that patients should be aware of.

We will discuss how muscle weakness can occur as a result of dexamethasone use and explain the condition known as corticosteroid-induced myopathy. Understanding the symptoms associated with this condition is essential for anyone taking dexamethasone, as it can significantly affect daily activities and overall health.

Additionally, we will explore strategies for managing potential muscle weakness while on dexamethasone, including the importance of monitoring symptoms, dosage adjustments, and engaging in supportive exercises. It's vital to maintain an open line of communication with your healthcare provider to ensure the best possible outcomes while using this medication.

Join us for this detailed discussion on dexamethasone and its effects on muscle strength. Don't forget to subscribe to our channel for more helpful information on pain medicine and management.

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Is Pristiq the Perfect Antidepressant? | How It Works, Side Effects, and Comparisons Side Effects 3 Views • 5 months ago

Welcome to our in-depth look at Pristiq! Whether you're taking it, considering it, or just curious, this video covers everything you need to know about Pristiq (desvenlafaxine), an SNRI used for major depressive disorder and menopausal hot flashes.

🔹 What is Pristiq?
Pristiq, a serotonin-norepinephrine reuptake inhibitor, is part of a class of medications including Effexor, Fetzima, and Cymbalta.

🔹 How Does Pristiq Work?
Pristiq boosts serotonin and norepinephrine levels, crucial for mood regulation, helping to alleviate depression symptoms.

🔹 Effectiveness of Pristiq
Users report significant improvements, especially those who haven't responded to other treatments. Clinical studies confirm its effectiveness.

🔹 Side Effects of Pristiq
Common side effects: nausea, dizziness, sweating, and insomnia. Serious side effects: increased blood pressure, agitation, and sexual issues. Always discuss with your doctor.

🔹 Serotonin Syndrome
A rare but serious condition from serotonergic drugs. Symptoms: seizures, irregular heartbeat, high fever. Seek medical help if needed.

🔹 Comparing Pristiq to Other Antidepressants
Compared to Effexor, Pristiq is easier to tolerate, has fewer drug interactions, can be taken with or without food, and is cost-effective as a generic.

🔹 Is Pristiq the Perfect Antidepressant?
Pristiq might be ideal for some but not for others. It's about finding the right fit for your needs. Not recommended for those with high blood pressure, agitation, or insomnia.

🔹 Conclusion
The best antidepressant is the one that works for you with manageable side effects. Consult your healthcare provider for the best treatment plan.

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Effexor (Venlafaxine) VS Pristiq (Desvenlafaxine) What you NEED to Know! Side Effects 2 Views • 5 months ago

In this video, we compare two serotonin norepinephrine reuptake inhibitors, Effexor (venlafaxine) and Pristiq (desvenlafaxine).
Intro: 0:00
How do Effexor and Pristiq work 0:33
What are Effexor and Pristiq used for 2:23
Common Side Effects of Effexor and Pristiq 2:53
Considerations of Effexor and Pristiq 4:53
Final thoughts 7:44

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Stahl's Prescribing Guide: https://amzn.to/3UXj8QL

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References:
Effexor ER (venlafaxine ER) FDA Label (2017). Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Pristiq (2018) FDA Drug Label. Retrieved from https://www.accessdata.fda.gov..../drugsatfda_docs/lab
Rege, S. (2022). Venlafaxine (Effexor) and Desvenlafaxine (Pristiq)- Mechanism of action, differences, psychopharmacology and clinical application. Psyc Scene Hub, https://psychscenehub.com/psyc....hinsights/venlafaxin
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
UpToDate (2023). Desvenlafaxine: Drug Information. Retrieved from https://www-uptodate-com.libproxy.eku.edu/contents/desvenlafaxine-drug-information?search=desvenlafaxine&source=panel_search_result&selectedTitle=1~23&usage_type=panel&kp_tab=drug_general&display_rank=1#F6107525
UpToDate (2023). Venlafaxine: Drug Information. Retrieved from https://www-uptodate-com.libproxy.eku.edu/contents/venlafaxine-drug-information?search=venlafaxine&source=panel_search_result&selectedTitle=1~148&usage_type=panel&kp_tab=drug_general&display_rank=1

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