Fatal Side Effects

The Pros and Cons of Codeine What You Need to Know
The Pros and Cons of Codeine What You Need to Know Side Effects 3 Views • 5 months ago

Codeine is one of the most widely used opioids, and is often prescribed to treat pain, cough, and diarrhea. While it can be a useful medication, there are also potential risks.
Before taking codeine, it’s important to understand the pros and cons of the drug and be aware of the potential side effects.
Codeine is an opioid pain medication, and is classified as a narcotic.
It affects the central nervous system and can be used to treat mild to moderate pain, as well as control coughing.
It is available in both prescription and over-the-counter forms, such as pills, syrups, and tablets.
Codeine can have a number of benefits but it should be used cautiously due to its addictive potential and the risk of side effects.
This article will discuss the pros and cons of codeine and what you need to know when considering taking it.

What is Codeine?

Codeine is an opioid pain medication that is classified as a narcotic.
It is derived from the opium poppy plant, and it acts on the central nervous system to produce a calming effect.
It is commonly used to treat mild to moderate pain, as well as control coughing.
Codeine is available in both prescription and over-the-counter forms, such as pills, syrups, and tablets.
It is also available in combination with other drugs, such as acetaminophen and ibuprofen.

The most common way to take codeine is orally, either in pill form or as a syrup.
Codeine can also be injected, but this is not recommended due to the risk of serious side effects.
When taken as prescribed, codeine can be effective in treating pain and controlling coughing.
However, it can also be abused and lead to addiction, so it should be taken with caution.

Benefits of Codeine

Codeine can be a useful medication for treating pain and controlling coughing.
It is often prescribed for short-term use to treat mild to moderate pain, such as after surgery or an injury.
It is also used to control coughing that is associated with the common cold, bronchitis, and other respiratory illnesses.

Codeine is generally considered safe when taken as prescribed, and it can be effective in relieving pain and controlling coughing.
It is also relatively inexpensive, making it a cost-effective option for those who need short-term relief.

Potential Risks of Codeine

While codeine can be effective in treating pain and controlling coughing, it also has potential risks.
As with any medication, there is a risk of side effects, particularly when taken in high doses or for extended periods of time.
Codeine can also be habit-forming, so it should be taken with caution.

Codeine is a narcotic, so it has the potential for misuse and abuse.
It can also interact with certain medications and supplements, so it’s important to talk to your doctor before taking codeine.
Additionally, codeine is not recommended for people with certain medical conditions, such as kidney or liver disease, or a history of addiction.

Side Effects of Codeine

Codeine can cause a variety of side effects, including nausea, vomiting, constipation, drowsiness, dizziness, and confusion.
It can also cause slowed breathing, which can be dangerous, especially in children and people with certain medical conditions.
Additionally, codeine can cause allergic reactions, such as rash, hives, and difficulty breathing.
It can also interact with other medications, so it’s important to talk to your doctor before taking codeine.

It’s important to be aware of the potential side effects of codeine and to be aware of any changes in your symptoms.
If you experience any concerning symptoms, such as difficulty breathing or an allergic reaction, you should seek medical attention immediately.

How to Safely Take Codeine

Codeine can be effective in treating pain and controlling coughing, but it should be taken with caution.
It is important to follow your doctor’s instructions when taking codeine and never take more than the recommended dose.

"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.

Opioids: How They Affect Your Brain & Signs of Withdrawal | Stanford
Opioids: How They Affect Your Brain & Signs of Withdrawal | Stanford Side Effects 4 Views • 5 months ago

What are opioids, and how do they affect our brains? What are the signs of opioid withdrawal? Dr. Anna Lembke, an addiction medicine physician, answers 8 of the most common questions she hears about opioids and opioid use disorder / opioid addiction in this video:
• What is an opioid?
• Is heroin an opioid?
• Is codeine an opioid?
• Is meth an opioid?
• Is suboxone an opioid?
• How is suboxone different from other opioids?
• How long do opioids stay in urine?
• What are the signs and symptoms of opioid withdrawal?

0:00 Introduction
0:08 What is an opioid?
1:15 Heroin
2:05 Codeine
2:25 Meth
2:40 Suboxone
6:42 How long do opioids stay in urine?
7:16 Withdrawal symptoms

Dr. Anna Lembke is Professor and Medical Director of Addiction Medicine at the Stanford University School of Medicine. Dr. Lembke was one of the first in the medical community to sound the alarm regarding opioid overprescribing and the opioid epidemic. Her clinical focus is on Addiction Medicine, Pain and Addiction, Prescription Drug Misuse and Addiction, and Behavioral Addictions.

The information in this video was accurate as of the upload date, 5/9/2022. For information purposes only. Consult your local medical authority or your healthcare practitioner for advice.

This video is a production of the Stanford Center for Health Education team, in collaboration with Stanford Medicine and the Stanford Center for Professional Development.

At the Stanford Center for Health Education, we believe that expanding access to engaging education has the power to change behaviors, improve health, and save lives.

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What is Codeine used for? Common Uses, Benefits, Potential Effects, Dosage and Dangers
What is Codeine used for? Common Uses, Benefits, Potential Effects, Dosage and Dangers Side Effects 2 Views • 5 months ago

Codeine: Uses, Benefits, Adverse Effects, Dosage Recommendations, and Dangers

Common Uses: Codeine is an opioid medication commonly used to treat mild to moderately severe pain. It is often prescribed when over-the-counter pain relievers such as acetaminophen or ibuprofen are insufficient. Additionally, codeine is frequently used as a cough suppressant, helping to reduce the urge to cough in conditions such as bronchitis or other respiratory illnesses.

Benefits: The primary benefit of codeine is its effectiveness in pain relief and cough suppression. As an opioid, it works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and reducing the cough reflex. This can significantly improve the quality of life for patients dealing with chronic pain or persistent coughing.

Potential Adverse Effects: Like all medications, codeine has potential adverse effects. Common side effects include:

Drowsiness and Dizziness: Codeine can cause significant sedation, which may impair the ability to perform tasks requiring alertness, such as driving.

Constipation: Opioids, including codeine, commonly cause constipation, which can be managed with dietary adjustments or laxatives.

Nausea and Vomiting: These are frequent side effects but can often be managed with antiemetic medications.

Respiratory Depression: In higher doses, codeine can depress the respiratory system, which can be dangerous and potentially life-threatening.

Addiction and Dependence: Prolonged use of codeine carries the risk of developing a physical dependence or addiction, characterized by the compulsive need to continue using the medication despite harmful consequences.

Dosage Recommendations: Dosage of codeine should be carefully determined by a healthcare professional based on individual patient needs and conditions. Typical doses for adults include:

Pain Relief: 15-60 mg every 4-6 hours as needed, not exceeding 360 mg in 24 hours.
Cough Suppression: 10-20 mg every 4-6 hours, not exceeding 120 mg in 24 hours.
It's crucial to follow the prescribed dosage and not to self-medicate or adjust the dose without consulting a healthcare provider.

Dangers: The dangers associated with codeine primarily revolve around its potential for misuse and the resultant health complications. Some major dangers include:

Overdose: Taking higher than recommended doses can lead to overdose, which may result in respiratory failure, coma, or death. Symptoms of overdose include extreme drowsiness, confusion, and difficulty breathing.

Tolerance and Dependence: Over time, users may develop tolerance, requiring higher doses to achieve the same effect, increasing the risk of dependence and addiction.

Withdrawal Symptoms: Abruptly stopping codeine after prolonged use can lead to withdrawal symptoms such as agitation, anxiety, muscle aches, insomnia, and gastrointestinal distress.

Interactions with Other Substances: Codeine can interact with alcohol and other medications, particularly other central nervous system depressants, leading to enhanced sedative effects and increased risk of severe respiratory depression.

In conclusion, while codeine is an effective medication for pain relief and cough suppression, it carries significant risks if not used correctly. It is essential to use codeine under strict medical supervision, adhere to prescribed dosages, and be aware of its potential adverse effects and dangers. Always consult with a healthcare provider for a tailored treatment plan and to mitigate risks associated with codeine use.

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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately."

Opioid Withdrawal
Opioid Withdrawal Side Effects 1 Views • 5 months ago

While opioid withdrawal can feel unbearable, effective treatment programs can help keep withdrawal symptoms controlled and can help people reduce or discontinue using opioids. If you or someone close to you needs help for a substance use disorder, talk to your doctor or call SAMHSA’s National Helpline at 1-800-662-HELP or go to SAMHSA’s Behavioral Health Treatment Services Locator at https://findtreatment.samhsa.gov/

#OpioidWithdrawal #RecoveryMonth

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Psych Hub is an educational service, and the information in this video is not a substitute for professional advice, diagnosis, or treatment. If you or someone you know are experiencing what you believe are mental health symptoms, please consult with a trained medical professional or a licensed mental health provider. We recommend consulting with a licensed behavioral health provider before trying any of the strategies mentioned in our materials.

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Kids getting codeine in ER despite risks
Kids getting codeine in ER despite risks Side Effects 3 Views • 5 months ago

CHICAGO (AP) -- Despite recommended limits on codeine use in children, the potent painkiller is prescribed for children in at least half a million emergency room visits each year, a study suggests.

Use of the drug in that setting is hardly rampant - just 3 percent of kids' ER visits resulted in a codeine prescription in 2010, the 10-year study found. But with more than 25 million ER visits by children each year, the authors say far too many kids are getting the drug when better options are available.

THE CONCERNS

Codeine is an opiate drug and a genetic variation makes some people metabolize it too quickly, potentially resulting in dangerous side effects including excessive sleepiness and difficulty breathing. The Food and Drug Administration issued its strictest warning last year about a rare risk for life-threatening complications or death in children given the drug after certain surgeries. It advises using codeine for children's pain only if anticipated benefits outweigh the risks.

Another genetic variation makes the drug ineffective for pain relief in as many as a third of patients. Codeine was once commonly used for coughs, but the American Academy of Pediatrics recommends against that use because of the risks and no evidence it relieves coughs.

THE FINE PRINT

Injuries and respiratory symptoms are the top reasons for children's ER visits. The study authors analyzed 2001-10 national data on ER visits for kids aged 3 to 17. The portion of visits where codeine was prescribed dipped slightly during the study. But the authors estimated the yearly number of codeine visits ranged from almost 560,000 to 877,000. Information on any side effects was not included in the data.

The study was published online Monday in Pediatrics.

WHAT DO DOCTORS SAY?

Dr. Kathleen Neville, a pediatric drug expert at Children's Mercy Hospitals and Clinics in Kansas City, said it's likely the numbers have declined since the study ended, given the FDA's black box warning.

Dr. Bradley Berg, medical director of McLane Children's Clinic in Round Rock, Texas, said some ER doctors may have been unaware of pediatricians' guidelines on limiting codeine's use, or recalled getting the drug themselves as children, when its use was more common, with no ill effects.

Dr. Alfred Sacchetti, a spokesman for the American College of Emergency Physicians, says codeine can be safely used in many children, especially older kids. Children typically are monitored in the ER after getting codeine and would not be sent home with a prescription if they had a bad reaction or it didn't work, he said.

THE ADVICE

Children on codeine who develop breathing problems or unusual sleepiness should get immediate medical attention, the FDA says. The study's lead author, Dr. Sunitha Kaiser, an associate pediatrics professor at the University of California, San Francisco, says doctors and parents should know about codeine's drawbacks and that alternatives are available, including dark honey for coughs in children over age 1

How I got off prescription opioids and got my life back | This Happened To Me
How I got off prescription opioids and got my life back | This Happened To Me Side Effects 3 Views • 5 months ago

Kirk Foat severely injured his hand while on vacation, so badly that when he returned to Canada, doctors feared they might have to amputate it. He underwent four surgeries to rebuild his hand, and was prescribed opioids to help with the pain.

But the opioids came with side effects, and eventually, for Kirk, didn't block his pain as well anymore. He decided to wean himself off the pills, once and for all. He shared the challenges of his experience with Dr. Brian Goldman on White Coat, Black Art.

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Codeine And The Side Effects
Codeine And The Side Effects Side Effects 0 Views • 5 months ago

https://addictiontreatments101.com/ Codeine And The Side Effects

When codeine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly.

If you or a loved one is looking for help with drug abuse, call our 24/7 helpline. A caring health care specialist is awaiting your call.

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Codeine Withdrawal, Addiction and Treatment - All You Need to Know About Codeine | ANR Clinic
Codeine Withdrawal, Addiction and Treatment - All You Need to Know About Codeine | ANR Clinic Side Effects 3 Views • 5 months ago

Codeine Withdrawal Addiction and Treatment - Click here for more information:
https://anrclinic.com/codeine-withdrawal-detox/

Codeine is an opiate used to treat pain, coughing, and diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol or a nonsteroidal anti-inflammatory drug such as aspirin or ibuprofen.

People may develop an addiction to codeine after continued use and/or abuse of the drug. Codeine users often get a false sense of security because codeine is not considered as powerful or addictive as other opiate family members such as heroin.

Some signs of codeine abuse include:
• Drowsiness
• Slurred speech
• Short attention span
• Impaired judgment
• Dilated pupils
• Lack of coordination
• Apathetic behavior

Long term signs of codeine abuse include:
• Depression
• Anxiety
• Fatigue
• Impaired memory
• Liver damage
• Kidney damage
• Muscle spasms
• Death
• Codeine withdrawal symptoms

Codeine withdrawal symptoms are very similar to the symptoms of withdrawal of other opiates such as morphine. Codeine withdrawal symptoms are usually not life-threatening, making some people try to quit cold-turkey. Unfortunately, unpleasant withdrawal symptoms often lead to relapse.

Codeine withdrawal symptoms vary from person to person, as does the severity and duration of the process of withdrawal.

Accelerated Neuro-Regulation or ANR treatment offers radically different results. The entire procedure lasts four to five hours, requiring a patient to stay in a specialized hospital for about 30 hours. There is no danger of relapse since the procedure treats the root causes of addiction on the physical, biological level.

The ANR treatment is based on advanced scientific research and medical advancements, as well as 30 years of clinical work of Doctor Andre Waismann. It is Dr. Waismann who identified the biological and physical roots of opioid dependency in the ’90s. During his illustrious career, Dr. Waismann has given numerous lectures and educated health professionals all over the world. The success of Dr. Waismann’s ANR treatment is directly related to the ability to evaluate the balance of endorphin-receptors in each patient and being able to bring each individual to his or her optimal chemical balance.

ANR is the only treatment in the world that addresses the root of opioid addiction.

---------------------------------------------------------------------------------------------------------------------------
Dr. Waismann identified the biological roots of opioid dependency; since then, he has successfully treated more than 24,000 patients worldwide that are struggling with opioid addiction.

Throughout his career, he has lectured and educated health professionals in dozens of countries around the world to this day.
---------------------------------------------------------------------------------------------------------------------------
For more information about Dr. Waismann's ANR Treatment:
ANR® Clinic - Advanced Opioid Treatment Center
Address: 2002 N Lois Ave Suite 150, Tampa, FL 33607, United States
Phone: 813-734-7036
--------------------------------------------------------------------------------------------------------------------------
Codeine or 3-methylmorphine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is often sold as a salt in the form of either codeine sulfate or codeine phosphate in the United States and Australia; codeine hydrochloride is more common worldwide and the citrate, hydroiodide, hydrobromide, tartrate, and other salts are also seen. Codeine is the second-most predominant alkaloid in opium, at up to three percent. Although codeine can be extracted from natural sources, a semi-synthetic process is the primary source of codeine for pharmaceutical use. It is considered the prototype of the weak to midrange opioids. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. It is the most commonly taken opiate. It is on the WHO Model List of Essential Medicines, a list of the most important medication needed in a basic health system.

Formula: C18H21NO3
Other names: 3-Methylmorphine
Onset of action: 15–30 minutes
Elimination half-life: 2.5–3 hours
Duration of action: 4–6 hours
Addiction liability: High

#codeine #opioids #opioidaddiction

What Are The Side Effects Of Codeine? - Pain Medicine Network
What Are The Side Effects Of Codeine? - Pain Medicine Network Side Effects 2 Views • 5 months ago

What Are The Side Effects Of Codeine? In this informative video, we will discuss the important aspects of codeine and its potential side effects. Codeine is a medication commonly prescribed for managing pain, but it is essential to be aware of the various reactions it may cause. We will cover common side effects that many individuals may encounter, as well as more serious concerns that could arise with use. Understanding these effects can help you make informed decisions about pain management.

We will also touch on how genetic factors can influence the way codeine is metabolized in the body, which can impact both its effectiveness and the likelihood of experiencing side effects. It is vital to have this knowledge when discussing treatment options with healthcare providers.

Join us as we navigate the complexities of codeine use and its implications for pain management. Whether you are considering codeine for your pain or are simply seeking to understand more about this medication, this video will provide you with essential information. Remember to consult with a healthcare professional before making any changes to your medication regimen.

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About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

DASHFIRE Week in REEEview: LDZ Reacts [ 8.2 - 8.8 2025]  Part 2
DASHFIRE Week in REEEview: LDZ Reacts [ 8.2 - 8.8 2025] Part 2 Side Effects 2 Views • 5 months ago

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Warnings over addictive opioids as nearly 12 million adults in England take them | 5 News
Warnings over addictive opioids as nearly 12 million adults in England take them | 5 News Side Effects 2 Views • 5 months ago

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► Britain is facing a drugs crisis, as many people rely on highly addictive prescription drugs.

One in four adults in England take sleeping tablets, anti-depressants or painkillers for far longer than they should - and the struggle to get off them can seem impossible.

Health chiefs say that although GPs need to stop handing them out, sometimes they are left with little choice.

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Side effects of taking codeine tablets - how long does codeine withdrawal addiction symptoms last
Side effects of taking codeine tablets - how long does codeine withdrawal addiction symptoms last Side Effects 3 Views • 5 months ago

Side effects of taking Codeine tablets. A video on the side effects of taking codeine tablets and learn how long does codeine withdrawal and addiction symptoms last . A narcotic that’s typically used to reduce coughing and relieve mild forms of pain. However, it’s easy to fall into a viscous cycle of addiction to the drug, and getting out of it can be tough. People trapped in the cycle typically suffer from some seriously unpleasant side effects.

These include drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting…and that’s just the tip of the addictive iceberg. Some even experiences stomach pain, excessive sweating, constipation, flushing, itching…and rashes.

These side effects are usually worsened when the drug is mixed with alcohol or other medications. Even HERBAL supplements can fuse with Codeine to create a potentially lethal combination.

Yes, the reality of Codeine addiction (and its side-effects) are frightening. But it doesn’t have to be this way. If you or anyone you know is ready to escape this prison, get in touch with Blvd Treatment Centers today. Help is always just a phone call away. Visit
http://BlvdCenters.org today for more helpful tips & resources.

If you or a loved one feels a need to overcome a codeine addiction, visit http://www.BlvdCenters.org or call (866) 583-2384 to speak to an Addiction Counselor. At BLVD we custom tailor our recovery programs within the safe and nurturing confines of our rehab treatment centers. Our mission is to assess the severity of your addiction to help you achieve true and lasting recovery.

Quitting codeine can be difficult. However, with hard work, dedication, and a strong will to stop abusing codeine, you can enjoy a substance-free lifestyle.

To help avoid relapse, you’ll be encouraged to take part in a group workshop to shore up your newly discovered sobriety, and keep you on the road to a clean lifestyle.

Along with helping you recover from codeine dependence, our qualified healthcare professionals will also help you identify your emotional triggers.

Codeine Phosphate : What is Codeine Used For? Codeine Uses, Dosage, Side Effects & Precautions
Codeine Phosphate : What is Codeine Used For? Codeine Uses, Dosage, Side Effects & Precautions Side Effects 3 Views • 5 months ago

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- This is lesson n# 27 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Codeine Phosphate : What is Codeine Used For? Codeine Uses, Dosage, Side Effects & Precautions

- In less than 3 minutes you'll learn about:

- What is Codeine?

- Codeine is a Narcotic analgesic and also an antitussive agent. It stimulates opiate receptors in the CNS, it binds to opiate receptors and blocks ascending pain pathways; reduces patient’s perception of pain without altering cause of the pain.

Also causes respiratory depression, peripheral vasodilation, inhibition of intestinal peristalsis, stimulation of the chemoreceptors that cause vomiting, increased bladder tone and suppression of cough reflex.

- It is available as 15 mg, 30 mg, 60 mg tablets. and also available as tablets and effervescent combined with paracetamol.

- Codeine is used to relief of mild to moderate pain, alone or in combination with a non-opioid analgesic, and also used for cough suppression.

- Learn more about Codeine mechanism of action, uses, dosage, side effects, and precautions in this video...

- MORE DRUG INFO HERE:
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Clozapine tablets ip | Clozapine tablets 100mg | clozapine side effects
Clozapine tablets ip | Clozapine tablets 100mg | clozapine side effects Side Effects 1 Views • 5 months ago

Clozapine is an antipsychotic medicine. Clozapine tablets ip uses to treat several metal disorders which are discussed in this video.
Clozapine tablets ip strength
1. Clozapine 12.5 mg tablet
2. Clozapine 25 mg tablet
3. Clozapine 50 mg tablet
4. Clozapine 100 mg tablet
5. Clozapine 200 mg tablet
Clozapine tablets brand names
1. Sizopin tablet
2. Skizoril tablet
3. Clozaril tablet
4. Lozapin talet
5. Zaporil tablet
This video contains information about Clozapine tablets ip | Clozapine tablets 100mg | clozapine side effects including
1. What is clozapine?
2. Clozapine tablet strength
3. Clozapine tablets brand name
4. Clozapine tablets ip uses in hindi
5. Clozapine tablet side effects
6. Clozapine tablets dosage
7. Clozapine tablet mechanism of action
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Clozapine Key Facts
Clozapine Key Facts Side Effects 3 Views • 5 months ago

Full interactive content videos now available at www.psychstudentinteractive.com

This video gives an overview of the complex antipsychotic clozapine. This information is up to date at the time of publishing but for up to date information please consult your local prescribing guidance or BNF particularly if prescribing for an off-licence indication. This video describes key factors in the commencement of clozapine and side effects or problems to watch out for. Whilst in the UK clozapine must be initiated by a consultant psychiatrist ongoing prescriptions and monitoring are the responsibility of the whole team and it is a medication which is often used when writing exam questions.

Disclaimer: please ensure you are reviewing up to date guidance and local policies when prescribing and monitoring clozapine. Psychstudent takes no responsibility for prescribing or clinical decisions. This information is correct at the time of publishing for use in England.

Long-term Effects of Antipsychotics on the Brain
Long-term Effects of Antipsychotics on the Brain Side Effects 2 Views • 5 months ago

In this video, we uncover the long-term and often irreversible effects of antipsychotic drugs, including brain volume loss, tardive dyskinesia, and cognitive decline.

Most doctors don't discuss these risks in detail, and patients are left unaware of the potential damage caused by these medications.

We’ll explore the evidence from both animal and human studies, explain how these medications affect your brain, and discuss what you can do to mitigate the risks.

If you or a loved one is on antipsychotics, this information is essential to understand the potential long-term consequences.

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🔗 LINKS MENTIONED
- Dorph-Petersen KA, Pierri JN, Perel JM, et al. (2005). The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: A comparison of haloperidol and olanzapine in macaque monkeys. Neuropsychopharmacology, 30, 1649–1661.**
- Fusar-Poli P, Smieskova R, Kempton MJ, Ho BC, Andreasen NC, Borgwardt S. Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies. Neurosci Biobehav Rev. 2013 Sep;37(8):1680-91. doi: 10.1016/j.neubiorev.2013.06.001. Epub 2013 Jun 14. PMID: 23769814; PMCID: PMC3964856.
- Wu JQ, Chen DC, Xiu MH, Tan YL, Yang FD, Kosten TR, Zhang XY. Tardive dyskinesia is associated with greater cognitive impairment in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1;46:71-7. doi: 10.1016/j.pnpbp.2013.06.013. Epub 2013 Jul 1. PMID: 23827756.
- https://www.psychiatrictimes.c....om/view/tardive-dysk
- Moncrieff J, Leo J. A systematic review of the effects of antipsychotic drugs on brain volume. Psychol Med. 2010 Sep;40(9):1409-22. doi: 10.1017/S0033291709992297. Epub 2010 Jan 20. PMID: 20085668.

Timestamps:
05:05 Brain Shrinkage and Its Implications
10:04 Movement Disorders: Tardive Dyskinesia Explained
15:11 Cognitive Decline and Long-Term Effects
16:33 Preventative Measures and Alternatives

‼️ DISCLAIMER: All the information on this channel is for educational and/or entertainment purposes and not intended to be specific/personal medical advice from me to you. Watching the videos, or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, these videos can maybe help you prepare for your discussion with him. We do our best to spread awareness with these videos, but for legal reasons we can’t answer health questions in the comments. If you leave questions, we’ll make videos about common questions in the future! If we catch incorrect health information, hate speech, illegal solicitation of drugs in the comments, we will remove them.

The Best Antipsychotic Medication in The World
The Best Antipsychotic Medication in The World Side Effects 2 Views • 5 months ago

Clozapine is the single most effective antipsychotic available, and it works in treatment resistant schizophrenia where no other medication is proven to be effective. This video will tell you everything you need to know about this important medication.

Time Stamps:
Topic Intro: 00:00 to 00:32
Old Vs New Medications: 00:33 to 01:20
Efficacy of Clozapine 01:21 to 03:10
Side Effects: 03:11 to 06:39
Mechanism of Action: 06:40 to 9:28
Important steps before starting the medication: 09:29 to 12:28
Dosing: 12:29 to 14:23

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Disclaimer: This is not medical advice, and the information is provided for educational purposes only. Please consult your doctor for any specific medical questions.

All content is created for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider. If you think you have a medical emergency, call your doctor, go to the emergency department, or call 911. We do not endorse any specific treatment, tests, or procedures. Reliance on this information is solely at your own risk.

Clozapine: Understanding Benefits and Barriers
Clozapine: Understanding Benefits and Barriers Side Effects 1 Views • 5 months ago

NAMI Ask the Expert Webinar welcomes Robert O. Cotes, M.D., Director of the Clinical & Research Program for Psychosis at Grady Health, Emory University School of Medicine, who discusses the unique and potentially life-changing benefits of clozapine, an antipsychotic medication used to treat symptoms of schizophrenia.
-
Currently, the American Psychiatric Association guidelines recommend a trial of clozapine if a person still has symptoms despite two prior trials of other antipsychotic medications. However, despite its effectiveness, clozapine is underutilized in the U.S. and often treated as a “last resort” option.
-
In this presentation, Dr. Cotes helps individuals and families better understand clozapine’s benefits, side effects and recent changes to the FDA’s Risk Evaluation and Mitigation Strategy regarding the drug.
-
If you or a loved one is seeking mental health treatment or additional information on mental health:
• Visit our website at NAMI.org.
• Call our HelpLine at 1-800-950-NAMI (6264) or text “HELPLINE” to 62640, open Mon-Fri from 10 a.m. to 10 p.m.
• Find your local NAMI at nami.org/findsupport
• If you or a loved one is experiencing a crisis, please call or text 988, available 24/7
-
NAMI, the National Alliance on Mental Illness, is the nation’s largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness.

Clozapine ( Clozaril ): What is Clozapine? Clozaril Uses, Dose, Adverse Effects & Precautions
Clozapine ( Clozaril ): What is Clozapine? Clozaril Uses, Dose, Adverse Effects & Precautions Side Effects 2 Views • 5 months ago

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- This is lesson n# 91 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Clozapine ( Clozaril ): What is Clozapine? Clozaril Uses, Dose, Adverse Effects, Precautions and mechanism of action

- In 3 minutes you'll learn:

- What is Clozapine ( Clozaril ): What is Clozapine? Clozapine uses, Side effects of Clozapine & Clozapine dose

- Clozapine is an antipsychotic medicine. It is a dopamine and serotonin antagonist in CNS. It also antagonizes adrenergic, cholinergic, and histaminergic neurotransmission.

- It is available as 25 mg, 50 mg,100 mg, and 200 mg tablets.

- Clozapine is used in the management of severely and chronically mentally ill schizophrenic patients who have not responded to or cannot tolerate standard antipsychotic drug treatment.

- Learn more about Clozapine ( Clozaril ) mechanism of action, uses, dosage, side effects, and precautions in this video...

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3 Most Serious Clozapine Side Effects
3 Most Serious Clozapine Side Effects Side Effects 2 Views • 5 months ago

In this video I talk about the 3 most serious side effects of Clozapine, those include: Agranulocytosis, Gastrointestinal hypomotility and myocarditis; Clozapine is a second generation antipsychotic medication
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Video Chapters
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0:35 Side effect 1: Agranulocytosis
2:33 Side effect 2: Gastrointestinal hypomotility
3:51 Side effect 3: Myocarditis
4:58 Other side effects

Clozapine
Clozapine Side Effects 5 Views • 5 months ago

Clozapine represents a breakthrough anti-psychotic medicine. Clozapine was introduced to the United States market in 1990 and is on the World Health Organization of essential medicines. Not only does Clozapine treat schizophrenia and related conditions, but it appears more effective than the standard anti-psychotic therapies. Clozapine also improves resistant schizophrenia and may additionally reduce the risk of suicide in these individuals.

Due to safety concerns that originated in Finland, the use of Clozapine has decreased. Current practitioners lack familiarity with this drug, and as a result of some negative publicity seem disinclined to prescribe it.

The two most worrisome issues involve a decline, sometimes serious, in the number of bacteria fighting neutrophils – a type of white blood cell. This occurs in about 3% of exposed individuals most commonly in the first 4 months of therapy. During this phase of Clozapine therapy, most recommend weekly laboratory tests.

Perhaps even more troublesome is a slowing of movement of muscular activity of gastrointestinal tract. This may lead to constipation, fecal impaction and bowel obstruction. Pre-emptive therapy with laxatives minimizes this issue. Other adverse drug reactions may occur.

In spite of the side effect profile, a recent study ranked Clozapine as the most effective drug in its class. As a generic, the financial burden it poses is minimal and more akin to the generic versions of Abilify, Zyprexa and Risperdal.

How to use Clozapine? (Clozaril, Leponex) - Doctor Explains
How to use Clozapine? (Clozaril, Leponex) - Doctor Explains Side Effects 2 Views • 5 months ago

In this video we will cover everything you need to know about Clozapine, also known as Clozaril. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

Generic name: Clozapine.
Brand names: Clozaril and Leponex.
Available as a tablet and a drink.

How to use it?
Swallow the tablet completely with half a glass of water.
When using it as a drink: measure the correct amount you need to take with a measuring spoon or measuring cup. And drink it.

Duration of treatment:
The duration of treatment depends on the indication of use and the severity of your symptoms. If your symptoms improve with the use of Clozapine you usually have to keep using it for 12-24 more months. And sometimes multiple years.

When to use it?
Clozapine is part of a group of drugs called antipsychotics. It can be used to treat several mental health conditions:
- Treatment-resistant schizophrenia.
- Treatment-resistant psychosis.
- Psychotic disorders in Parkinson's disease.
- Delirium in Parkinson's or 'Lewy body' dementia.

What is the correct dosage?
Unfortunately I can’t provide you with guidelines for the correct dosages, as these differ a lot depending on the specific indication, the side effects you experience and the severity of your complaints.
Usually your doctor starts with a low dose and quickly builds it up over a few days. Afterwards your maintenance dose will be adapted throughout your treatment based on the blood levels of Clozapine you will be having.
Therefore always use the prescribed dose and frequency your doctor gave you.

What are the side-effects?
Very common (10%): somnolence, dizziness, constipation and a fast heartbeat.
Common (1-10%): changes in your blood values, dry mouth, low blood pressure, high blood pressure, stomach and intestine complaints, weight gain, headache, tremor, stiffness, fatigue, fever and sweating.
Uncommon (0.1-1%): stuttering and falling.

Safety:
You should be careful to combine Clozapine with alcohol. As this might increase the dazing effect of Clozapine.
In addition it is usually safe to drive while using this drug, however it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects then please do not drive.
Furthermore, smoking cigarettes decreases the effectivity of clozapine. Always discuss this with your prescribing doctor.
Lastly, Clozapine can have interactions with several drugs. Therefore always discuss this with your treating physician.

Pregnancy and Lactation:
Clozapine can be dangerous in both cases, therefore always discuss this with your doctor.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

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Literature:
1: Farmacotherapeutisch Kompas. (2020). Clozapine
2: Apotheek.nl (2020). Clozapine.

* The images in this video are used for educational purposes only. Most of the images and video material in this video come from https://www.canva.com/.

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Clozapine Withdrawal, Tapering, and Clozapine Alternatives. Alternative to Meds Clozapine Help Video
Clozapine Withdrawal, Tapering, and Clozapine Alternatives. Alternative to Meds Clozapine Help Video Side Effects 4 Views • 5 months ago

Our treatment specialist and founder of ATMC, Lyle Murphy, answers your biggest concerns about the second generation antipsychotic drug Clozapine.


Clozaril is the brand name for the active ingredient, clozapine. Other brand names include Clopine, Clozapine Synthon, and FazaClo.



Q&A From you!

00:00 - Intro
00:20 - Why do so many doctors feel that Clozapine is the most effective medication for schizophrenia?
00:58 - Is clozapine a mood stabilizer?
01:21 - What are the worst side effects of clozapine?
03:13 - Why is clozapine called an atypical antipsychotic and not a benzodiazepine?
04:19 - Can clozapine cause tremors?
05:11 - What's next for the schizophrenic when clozapine fails? Doctors seem to always have another one ready?
06:04 - Could clozapine affect one's cognitive abilities/IQ?
08:31 - Is Clozapine worth the risk for those suffering from severe schizophrenia, considering how dangerous some of the side effects are?
10:07 - What antipsychotic is a good alternative to clozapine if you have to have something?
12:24 - Why would someone be prescribed a "therapeutic" dose of clozapine?
12:53 - Is olanzapine a better antipsychotic than clozapine if you worry about your physical health most?
15:20 - Which is less likely to cause tardive dyskinesia, olanzapine 2.5mg or clozapine 25mg?
15:55 - How long do antipsychotics withdrawal symptoms last from 2 months from 100 mg of Clozapine?
17:40 - What are the chances of a low dose (25mg) of clozapine causing tardive dyskinesia?
18:09 - Does a significant weight loss change the efficacy of clozapine?
19:04 - Can hypomotility caused by clozapine affect the absorption and efficacy of it?
20:32 - Will fasting for 24 hours affect the absorption of clozapine and cause a problem?
24:25 - ATMC

Careful Clozaril withdrawal can minimize the potential for rebound psychosis and cholinergic crises. Clozaril belongs to a class of drugs called SGA’s or second-generation antipsychotics.
Used in the treatment of certain mental conditions such as schizophrenia and psychosis, Clozaril is often prescribed only AFTER other antipsychotics did not work or caused severe side effects.
Alternative to Meds has been the expert on antipsychotic withdrawal and Clozaril alternatives for over 15 years. We have published evidence regarding our success. Underlying issues can in many cases be addressed in much less toxic ways. It is possible that some medical conditions could have been overlooked. Commonly some or all of the original contributing factors have improved or changed, and the diagnosis one was given may no longer lead to recovery.


What Is Clozaril (clozapine) Used For?


Clozaril is used in the treatment of certain mental disorders, where other (usually at least two) other antipsychotic medications have not worked, or where the side effects were too harsh and could not be tolerated by the patient. A candidate for a prescription of Clozaril could be someone diagnosed with conditions such as:

Treatment-resistant schizophrenia.
Treatment-resistant schizoaffective disorder with a known risk for suicide.
Please note that elderly patients with dementia-related psychosis should NOT be prescribed Clozaril (or other antipsychotic medications) due to the increased risk of death.


Discontinuing/Quitting Clozaril (clozapine)
There are circumstances where immediate withdrawal of Clozaril is medically needed as a life-saving intervention. These include potentially life-threatening adverse reactions to the drug which are delineated in detail under the adverse effects section, for instance, cardiovascular compromise, risk of stroke, signs of tardive dyskinesia, and other severe reactions.

In the majority of cases, gradual Clozaril tapering methods are recommended for coming off the drug.

Always seek medical guidance and direction from your doctor before making changes to medications.

Read more at:
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Antipsychotic Medications - Pharmacology - Nervous System | @LevelUpRN
Antipsychotic Medications - Pharmacology - Nervous System | @LevelUpRN Side Effects 4 Views • 5 months ago

Cathy covers first-generation (typical) antipsychotic medications and second-generation (atypical) antipsychotic medications.

Our Pharmacology video tutorial series is taught by Cathy Parkes BSN, RN, CWCN, PHN and intended to help RN and PN nursing students study for their nursing school exams, including the ATI, HESI and NCLEX.

#NCLEX #Pharmacology #Nervous #HESI #Kaplan #ATI #NursingSchool #NursingStudent⁠ #Nurse #RN #PN #Education #LVN #LPN #Antipsychotic

0:00 What to Expect
0:09 Symptoms of Schizophrenia & Positive Symptoms
0:36 Negative Symptoms
0:59 Typical/First Generation Antipsychotics
1:18 Mode of Action
1:44 Side Effects
3:50 Atypical/Second Generation Antipsychotics
4:49 Mode of Action & Side Effects
5:49 Nursing Care
6:12 What’s Next

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Clozapine side effects: What causes sedation and what to do about it?
Clozapine side effects: What causes sedation and what to do about it? Side Effects 2 Views • 5 months ago

Clozapine is the most effective of all antipsychotic medications. And for many people with schizophrenia, clozapine is a game-changing treatment that makes it possible to go back to school, go back to work, live independently, or be in relationships.

It does have side effects (all medicines do), but many of them can be prevented or minimized.

Sedation is one of the most common of clozapine’s side effects, and this lecture talks possible causes and potential treatments for clozapine-associated sedation.

Here, we look at the prevalence of clozapine-associated sedation, discuss pharmacological actions of clozapine that may contribute to sedation, and survey some treatment strategies to reduce or eliminate this side effect.

If you’d like to learn more about clozapine, feel free to register for one of our free online continuing medical education events. The schedule of upcoming events is located at [https://clozapine.info/training/](https://www.youtube.com/redirect?v=HQGlvQKKQXc&redir_token=amza-r0-7tSq2dVsQQjGNF24oz98MTU4NjQzODg4NEAxNTg2MzUyNDg0&event=video_description&q=https%3A%2F%2Fclozapine.info%2Ftraining%2F)

The lecture is part of the SZconsult learning community, which meets every Tuesday at noon, eastern time. It’s a free education + consultation service of Northeast Ohio Medical University. For more information send an email to [email protected]

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Clozapine: Benefits, Reducing Side Effect Risks, and Alternatives
Clozapine: Benefits, Reducing Side Effect Risks, and Alternatives Side Effects 3 Views • 5 months ago

This is a recorded lecture. It was given at the monthly Psychosis Education Event in January, 2023. The monthly Psychosis Education Event consists of a free lecture on some mental health related topic, followed by an open-forum question/answer session with a psychiatrist and clinical psychologist. It is free of charge and open to the public. If you would like to join, send me a note via https://askapsychiatrist.info

Clozapine is the most effective medication for schizophrenia. It is the only medication with FDA approval for reducing suicide risk. About 30% of people with schizophrenia do not get significant benefit from standard antipsychotic medication -- yet in that subset of individuals, clozapine is successful in about 50% of cases (the success rate of other antipsychotic medications is about 7% to 14%).

This lecture discusses:
1. Why do some people with schizophrenia-like symptoms not respond to standard, first-line antipsychotic medications?
2. What are the unique advantages of clozapine?
3. What are the most common or worrisome clozapine side effects, and how can their risks be minimized?
4. Are there any alternatives to clozapine?

Clozapine (Clozaril) - Pharmacist Review - Uses, Dosing, Side Effects
Clozapine (Clozaril) - Pharmacist Review - Uses, Dosing, Side Effects Side Effects 3 Views • 5 months ago

In this episode, I discuss a medication known as clozapine (Clozaril).

My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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Intro Created by Leah Leblanc - leahleblanc.com

For information purposes only!

Clopidogrel: Para que serve e efeitos colaterais
Clopidogrel: Para que serve e efeitos colaterais Side Effects 3 Views • 5 months ago

Mantenha-se informado e proteja sua saúde com o @NEUROCIRURGIABR ! Nosso objetivo é oferecer informações confiáveis sobre neurocirurgia, condições neurológicas e as principais notícias de saúde do momento. Explore conteúdos sobre:

- Neurocirurgia: Tumores cerebrais, aneurismas, doenças da coluna e muito mais.
Saúde em Foco: Dicas de prevenção, bem-estar e as últimas descobertas médicas.
- Vacinação: Atualizações sobre campanhas, importância da imunização e combate a doenças.
- Doenças da Atualidade: Informações sobre surtos, epidemias e prevenção de doenças prevalentes.

Autor: Julio Pereira - Neurocirugião - São Paulo 🇧🇷 CRM/SP 163.113
Consulta:
http://drjuliopereira.com.br/ Consultório: (11)99503-8838 (WhatsApp) / (11)4200-2300
Atuando no Hospital Sírio-Libanês e na BP – A Beneficência Portuguesa de São Paulo.

A neurocirurgia é a especialidade médica que se dedica ao tratamento de doenças do sistema nervoso central e periférico, abrangendo desde recém-nascidos até adultos e, recentemente, fetos. Atuamos em uma ampla gama de condições, como:

Hidrocefalia
Tumores cerebrais e da coluna vertebral
Doenças vasculares (aneurismas, malformações arteriovenosas)
Doenças degenerativas (doença de Parkinson)
Traumatismos cranioencefálicos e lesões raquimedulares
Epilepsia
Dores crônicas
Distúrbios do movimento (distonias, síndrome de Tourette)
Alguns transtornos psiquiátricos (psicocirurgia)
Nosso objetivo é oferecer soluções cirúrgicas inovadoras e eficazes, visando melhorar a qualidade de vida dos pacientes.

http://weneuro.com/
http://radiocirurgia.com.br/

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Meus livros publicados:
1) Após um tumor cerebral
2) Escrito em letra de médico
3) Ultimas Cartas de um médico
4) Suturando Ideias
5) Neurocirurgia para o estudante de medicina

Quer ter acesso grátis aos livros? É só enviar um e-mail para [email protected] que mandamos em PDF.
Informações sobre alguma doença Neurológica ou sobre Neurocirurgia veja nos sites:

🤕 Tumor Cerebral https://tumor-cerebral.com/
😷 Radiocirurgia http://radiocirurgia.com.br/
🧠 Câncer https://www.neurocancer.com/
🫀 Aneurisma Cerebral https://aneurismacerebral.org/
👨🏽‍⚕️ Coluna e Dor https://cirurgianacoluna.com/
👨🏻‍🏫 Informações para Estudantes de Medicina http://weneuro.com/
👨‍🔬 Artigos Médicos: https://neurocirurgiabr.com/

⚠️ AVISO LEGAL:
As informações disponíveis neste vídeo são estritamente informativas, não substituindo o parecer médico/profissional. Sempre consulte o seu médico sobre qualquer assunto relativo à sua saúde e aos seus tratamentos e medicamentos.

Clopidogrel Patient Counseling
Clopidogrel Patient Counseling Side Effects 3 Views • 5 months ago

Kelsey Knight - Student Pharmacist

Clopidogrel Drug Information PDF:
https://drive.google.com/file/....d/1w7nZDzKXczmjdcnjE

0:11 - Uses
0:21 - Administration
0:28 - Missed Dose
0:39 - Side Effects
0:53 - What to tell your doctor
1:10 - Storage

Thanks for watching!

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