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In this video, Jim tries using a 2% ketoconazole shampoo for 3 months. Will he be able to reverse his hair loss? Stay tuned to find out!

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00:00 - Lamotrigina - Para que Serve e Quais os Riscos da Lamotrigina

No vídeo de hoje, eu vou falar sobre a lamotrigina. Se você quer saber para que serve lamotrigina, como funciona e quais os efeitos colaterais da lamotrigina, fique comigo até o final deste vídeo.

01:28 - Como a Lamotrigina Age

A Lamotrigina é um anticonvulsivante da classe das feniltriazinas, com menos efeitos colaterais que outros fármacos. Ela age bloqueando canais de sódio e cálcio, reduzindo a liberação de glutamato. Isso ajuda a controlar a hiperatividade neuronal e prevenir crises convulsivas.

02:31 - Indicações da Lamotrigina

A Lamotrigina é eficaz na epilepsia e no transtorno bipolar, principalmente na prevenção de episódios depressivos. Também é usada off-label para TEPT, dor neuropática central e dermatotilomania, com evidências promissoras. Seu efeito se deve à modulação do glutamato, ajudando na estabilização do humor e controle de sintomas compulsivos.

08:06 - Efeitos Colaterais da Lamotrigina

A Lamotrigina pode causar reações cutâneas em 6 a 10% dos pacientes, desde erupções leves até condições graves, como Síndrome de Stevens-Johnson e Necrose Epidérmica Tóxica, principalmente em crianças e ao usar Valproato. Também pode interagir com outros medicamentos, como anticonvulsivantes e contraceptivos orais, exigindo ajustes.

Neste vídeo:
Lamotrigina;
Para Que Serve Lamotrigina;
Como Funciona a Lamotrigina;
Como Tomar Lamotrigina;
Lamotrigina Para Transtorno Bipolar;
Lamotrigina Para Epilepsia.

Referências:
Bowden CL, et al. A randomized, placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed or manic patients with bipolar I disorder. Arch Gen Psychiatry. 2003;60(4):392-400.

Calabrese JR, et al. A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. J Clin Psychiatry. 1999;60(2):79-88.2

Cochrane Database of Systematic Reviews. Lamotrigine add-on for drug-resistant focal epilepsy. 2018.

Geddes JR, Miklowitz DJ. Treatment of bipolar disorder. Lancet. 2013;381(9878):1672-1682.

Ghaemi SN, Shirzadi AA, Filkowski M. A Meta-Analysis of Long-Term, Placebo-Controlled, Randomized Trials of Pharmacotherapy in Bipolar Disorder. Int J Neuropsychopharmacol. 2019;22(5):293-304.

Hertzberg MA, et al. A preliminary study of lamotrigine for the treatment of posttraumatic stress disorder. Biol Psychiatry. 1999;45(9):1226-1229.3

Pinto OC, Akiskal HS. Lamotrigine as a promising approach to borderline personality: an open case series without concurrent DSM-IV major mood disorder. J Affect Disord. 1998;51(3):333-343.4

Trinka E, et al. Safety and tolerability of lamotrigine: results from a pooled analysis of controlled clinical trials. J Clin Med Res. 2017;9(6):475-486.

Zakrzewska JM, et al. Lamotrigine (lamictal) in refractory trigeminal neuralgia: results from a double-blind placebo controlled crossover trial. Pain. 1997;73(2):223-230.5

Messina G, et al. Lamotrigine: Some Aspects of the Pharmacokinetics and the Efficacy in the Treatment of Epilepsy and Bipolar Disorder. Curr Drug Metab. 2019;20(7):530-536.

Lojko A, Suwalska A, Rybakowski J. Zastosowanie lamotryginy w zaburzeniach afektywnych – przegląd piśmiennictwa [The use of lamotrigine in affective disorders - a review of the literature]. Psychiatr Pol. 2017;51(4):641-651.

da Silva Júnior ED. Lamotrigina no tratamento do transtorno de personalidade borderline: uma revisão sistemática [Lamotrigine in the treatment of borderline personality disorder: a systematic review]. Revista Debates em Psiquiatria. 2018;8(2):24-31.

Vestergaard K, et al. Lamotrigine for central poststroke pain: a randomized controlled trial. Neurology. 2001;56(2):184-190.

McCleane G. Lamotrigine in the management of neuropathic pain: a review of 157 cases. The Clinical Journal of Pain. 2003;19(5):332-335.

Grant JE, et al. Lamotrigine treatment of pathologic skin picking: an open-label study. Ann Clin Psychiatry. 2007;19(4):223-230.

Atmaca M, et al. Lamotrigine augmentation in treatment-resistant obsessive-compulsive disorder: a 12-week open trial. J Clin Psychopharmacol. 2014;34(5):557-560.

Fontenelle LF, et al. A double-blind, randomized, placebo-controlled trial of lamotrigine for trichotillomania. Braz J Psychiatry. 2019;41(2):153-159.

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On this podcast episode, I discuss Clotrimazole pharmacology, adverse effects, indications, administration, and much more.






Clotrimazole is an imidazole antifungal that exerts its pharmacological effect by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This inhibition compromises membrane integrity, leading to leakage of cellular contents and ultimately fungal cell death.






Clotrimazole is primarily used topically due to poor systemic absorption when administered via the skin or mucous membranes, which limits systemic side effects.






When clotrimazole is used intravaginally or orally in lozenge form, localized concentrations are sufficient to treat mucocutaneous infections without significant systemic exposure.






Pay attention when clotrimazole is used frequently to treat Candida infections as corticosteroids, immunosuppression, and antibiotics may increase the risk of this type of infection.






Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE! (https://www.reallifepharmacolo....gy.com/100-free-phar




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هنتكلم عن كل المعلومات اللي لازم تعرفها قبل ما تستخدم دواء البلاكونيل أو الهيدروكسيكلوروكوين. هنتكلم عن مين اللي بيستخدمه، شكل الدواء، إزاي يتاخد، الأعراض الجانبية الشائعة والغير شائعة وكيف نحمي نفسنا منها.
ليه لازم نتابع مع طبيب العيون أو طبيب الرمد، وهنناقش آثاره على القلب واللي الناس اتكلمت عنها كتير في الفترة اللي فاتت بعد ما فشل في علاج فيروسات زي الكورونا.

شاهد أيضا السلاسل الأخرى على القناة:
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اشترك في قناة الاستشاري للأمراض الروماتيزمية والمناعية
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اشترك في قناة يوتيوب الاستشاري (القناة الأم) عشان يوصلك كل جديد
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تحياتي
د. حمدي محمد عبد العزيز
الاستشاري


المصادر:
1- RECOVERY trial investigators. No clinical benefit from use of hydroxychloroquine in hospitalised patients with COVID-19. https://www.recoverytrial.net/....news/statement-from-
2- NIH halts clinical trial of hydroxychloroquine https://www.nih.gov/news-event....s/news-releases/nih-
3- WHO discontinues hydroxychloroquine and lopinavir/ritonavir treatment arms for COVID-19 https://www.who.int/news-room/....detail/04-07-2020-wh
4- WHO. “Solidarity” clinical trial for COVID-19 treatments: Update on hydroxychloroquine. https://www.who.int/emergencie....s/diseases/novel-cor

5- Baer AN, Witter FR, and Petri M, "Lupus and Pregnancy," Obstet Gynecol Surv, 2011, 66(10):639-53
6- Bahloul E, Jallouli M, Garbaa S, et al. Hydroxychloroquine-induced hyperpigmentation in systemic diseases: prevalence, clinical features and risk factors: a cross-sectional study of 41 cases. Lupus. 2017;26(12):1304‐1308.
7- Balevic SJ, Cohen-Wolkowiez M, Eudy AM, Green TP, Schanberg LE, Clowse MEB. Hydroxychloroquine levels throughout pregnancies complicated by rheumatic disease: implications for maternal and neonatal outcomes.
8- Birru Talabi M, Clowse MEB. Antirheumatic medications in pregnancy and breastfeeding
9- https://www.accessdata.fda.gov..../drugsatfda_docs/lab

5 Things You Should Be Told When Starting Medication for Anxiety and/or Depression | SSRI/SNRI. When being prescribed medications like Zoloft, prozac, Paxil, Cymbalta, lexapro, celesta or Effexor, its important to receive information about those medications so that you are taking them as safely as possible. Here’s my top 5 things I always discuss when prescribing these types of medications.

For a more detailed video about Anxiety And Depression, check out these videos:
More about SSRI’s and SNRI: https://youtu.be/JKSXgf7Q2Co
My Experience Taking Zoloft: https://youtu.be/9D5jNDv2GDE


Need a Nursing Report Sheet or SOAP Note Template? Get yours for free here! https://www.subscribepage.com/v7g4z1

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Primary Care in a Pandemic: https://youtu.be/6RUIrnKsct0


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Hi! I’m Liz, a Family Nurse practitioner, former pediatric nurse and mom of two. My goal here is to share information about the nursing profession, and share life as a working mom along the way!


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As Covid Vaccine mandates become more popular, I have a few thoughts as to what is ethically the right move here. Covid vaccination decreases spread of illness, and will decrease likelihood of transmission to patients. However the vaccine mandate may cause more nurses to leave already short staffed units, making working conditions more unsafe. And costing more lives in the end.

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Enduring Activity: Updates in Pediatrics: Management of Antipsychotic Medications

Target Audience
This activity is targeted towards pediatricians, IM/P, and family practitioners.

Statement of Need
Our learners need the knowledge and strategies to assist in recognizing, evaluating and treating common and not so common problems presenting in a primary care setting, including when it is appropriate to refer.

Objectives
At the conclusion of this offering, the participant will be able to:
Define different types of antipsychotics.
Delineate the side effects of different antipsychotics.
Discuss the monitoring requirements for patients on antipsychotics.
Discuss when and how to start patients on antipsychotics.

Faculty
Felissa Goldstein, MD
Board Certified Adult, Adolescent and Child Psychiatrist
Division of Behavioral and Mental Health

Faculty Disclosure
Faculty for this course has no potential or actual conflicts of interest to disclose.

Planner Disclosure
Planners for this course have no potential or actual conflicts of interest to disclose.
Commercial Support
This activity has not received commercial support.
Accreditation
Norton Healthcare is accredited by the Kentucky Medical Association to provide continuing medical education for physicians.

Designation
Norton Healthcare designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Date of Original Release | March 17, 2021
Course Termination Date | December 2022
Contact Information | Center for Continuing Medical Education; (502) 446-5955 or [email protected]

Evaluation:
https://www.surveymonkey.com/r..../UpdatesinPedsEnduri

Resources:

Ferrin M, Gosney H, Marconi A, Rey J, “ Using Antipsychotic Medication for the treatment of Schizophrenia in Children and Adolescents,” IACAPAP Textbook of Childhood and Adolescent Mental Health, 2016
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC64834

Thomas T, Stansifer L, Findling RL. Psychopharmacology of pediatric bipolar disorders in children and adolescents. Pediatr Clin North Am. 2011 Feb;58(1):173-87, xii. doi: 10.1016/j.pcl.2010.10.001. PMID: 21281855.
https://www.clinicalkey.com/#!/content/playContent/1-s2.0-S0031395510001902?returnurl=https:%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0031395510001902%3Fshowall%3Dtrue&referrer=https:%2F%2Fpubmed.ncbi.nlm.nih.gov%2F

What Are Ketorolac Eye Drops For? In this informative video, we will discuss ketorolac eye drops and their role in eye care. These drops are a type of nonsteroidal anti-inflammatory medication used to manage various eye conditions. We will explain how ketorolac eye drops work to alleviate inflammation, pain, and allergic symptoms affecting the eyes.

You will learn about the situations in which these drops are commonly prescribed, including post-eye surgery recovery and the treatment of allergic conjunctivitis. We will also cover the benefits of using ketorolac eye drops, such as controlling discomfort without the side effects associated with steroids. Additionally, we will provide guidance on how to use these drops effectively, including storage tips and what to expect during application.

Whether you are recovering from eye surgery or dealing with allergy-related symptoms, understanding the use of ketorolac eye drops can help you manage your eye health more effectively. Join us as we break down the essential information you need to know about this medication. Don't forget to subscribe to our channel for more helpful content on eye care and optometry.

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#Ketorolac #EyeDrops #Optometry #EyeCare #AllergyRelief #PostSurgeryCare #Inflammation #PainManagement #EyeHealth #Conjunctivitis #Nonsteroidal #EyeDiscomfort #EyeMedication #Ophthalmology #VisionCare

About Us: Welcome to Optometry Knowledge Base, your go-to resource for all things related to optometry! Our channel is dedicated to providing in-depth insights into eye health, vision care, and the latest advancements in the field of optometry. Whether you're a student looking to deepen your understanding, a practicing optometrist seeking to stay updated, or simply someone interested in learning more about eye care, you’ll find valuable content here. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

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Video description:
Dr. Kneller discusses discuses treatment strategies for atrial fibrillation. Considerations include rhythm control (stopping and preventing atrial fibrillation) and rate control (slowing down the rapid heart rate caused by atrial fibrillation, without attempting to restore a normal rhythm), and whether systemic anticoagulation medication (ie, Xarelto, Eliquis, Pradaxa, or warfarin) is needed. Anti-arrhythmic medications (ie, flecainide, propafenone, sotalol, tikosyn) or catheter ablation are used to restore normal rhythm.

Is Tranexamic Acid the golden ray of hope for melasma cases? With this reel, let's understand the functioning of tranexamic acid in depth, how it helps aid Melasma and reiterate that it's a PRESCRIPTION DRUG!

So let's be mindful and consult a board-certified dermatologist before starting tranexamic acid. Stay safe, stay healthy!

To look and feel your best, book an appointment with
us today!
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Does Bumetanide Affect Potassium Levels? In this informative video, we will discuss the effects of Bumetanide on potassium levels and what you need to know if you are taking this medication. Bumetanide is a loop diuretic commonly used for conditions such as heart failure, kidney disease, and liver disease. While it is not typically the first-line treatment for hypertension, it can be part of a broader treatment strategy for managing blood pressure when combined with other medications.

We will explain how Bumetanide works by increasing urine production, which helps your body eliminate excess fluid and salt. However, this process may also lead to a decrease in potassium levels, potentially resulting in hypokalemia. We will cover the symptoms of low potassium and the importance of monitoring your levels while on this medication.

Staying hydrated and consuming potassium-rich foods are essential steps to help manage your potassium levels effectively. We’ll also highlight the significance of regular check-ups with your healthcare provider to ensure your electrolyte balance remains stable.

Join us in this essential discussion to better understand how Bumetanide interacts with potassium and how you can manage your health while on this medication. Don't forget to subscribe to our channel for more helpful information on hypertension and related topics.

⬇️ Subscribe to our channel for more valuable insights.

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#Bumetanide #PotassiumLevels #Diuretics #HypertensionManagement #HeartHealth #KidneyHealth #LiverHealth #ElectrolyteBalance #Hypokalemia #HealthTips #MedicationAwareness #StayHydrated #PotassiumRichFoods #BloodPressureControl #HealthyLiving #PatientEducation

About Us: Welcome to Hypertension Help Hub, your go-to channel for everything related to high blood pressure. Here, we provide clear and concise information on High Blood Pressure Basics, Causes of Hypertension, Symptoms, Blood Pressure Monitoring, and Lifestyle Changes for Hypertension. We cover essential topics such as the DASH Diet, Medications for High Blood Pressure, and effective strategies for managing stress to support heart health. Our goal is to equip you with practical tips for Hypertension Prevention and ways to take control of your well-being. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Trulicity (dulaglutide) and Ozempic (semaglutide) are medications used to treat Type 2 diabetes. They're taken in combination with diet and exercise.

Both medications may also lower the risk of heart attack, stroke, or death related to heart disease. But Trulicity is approved for this use in more people than Ozempic

Both Ozempic and Trulicity are GLP-1 medications that are indicated for the treatment of type 2 diabetes. However, Ozempic has also been approved by the FDA to support chronic weight management. Trulicity is only approved for the treatment of type 2 diabetes in adults.

Ozempic is a once-weekly injection used to treat Type 2 diabetes.
It's not approved for weight loss, but people taking it tend to lose weight. Wegovy is a higher-dose version of Ozempic that's approved specifically for weight loss

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Catch me on the Rickey Smiley Morning Show on 70 stations nationwide wkdays 6-10AM ET!

Make sure you subscribe to this channel and follow Dr. Collier on All His Social Media Platforms:
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We now have a Facebook Group so make sure you join the community there will be a lot of exciting things going on inside so make sure you join. www.facebook.com/groups/lipocares/

Ocrevus (ocrelizumab) and Kesimpta (ofatumumab) are two drugs for multiple sclerosis which both work on b-cells. In this video, I explain differences between the two drugs and results from clinical trials. Which drug has fewer drug-reactions? Which has a lower rate of serious infections? Is Kesimpta more optimally dosed?

Sources:

Subgroup analysis of OPERA trials: https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC64696

OPERA trials: https://www.nejm.org/doi/full/....10.1056/NEJMoa160127

NEJM article summarizing the ASCLEPIOS trials: https://www.nejm.org/doi/10.1056/NEJMoa1917246



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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.

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The video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.

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Drug Cards Daily | Episode #37: gabapentin (Neurontin) | For Seizures and Neuropathic Pain

Gabapentin has a wide variety of uses but the main indications are for focal seizures in adults and children and for postherpatic neuralgia in adults. There are many commonly used off label indications such as for neuropathic pain, fibromyalgia, and alcohol dependence. Max dosing for gabapentin is around 3600 mg/day. Although the exact mechanism of action is unknown, it is clear that it is similar in chemical structure to GABA. This is important because GABA is responsible for modulating excitatory neurotransmitter release. Gabapentin is poorly protein bound at less than 3% and not metabolized. When discontinuing longer term therapies, doses should be tapered down over at least 7 days. Some of the most common side effects are dizziness, fatigue, and weight gain. The serious side effects are depression, suicidal thoughts and behaviors, and withdrawal related seizures.

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Digoxin nursing pharmacology (NCLEX) mnemonic covering mechanism of action, toxicity, and side effects.

Study this Digoxin Nursing Pharmacology mnemonic for NCLEX and other mnemonics with Pixorize.

Digoxin is a cardiac glycoside that works by increasing the strength of the heart’s contractions and slowing down the heart rate. It is used clinically to treat atrial fibrillation and heart failure. Digoxin has a narrow therapeutic range, and side effects are seen above dose levels of 2 ng/mL. The risk of toxicity is increased with hypokalemia, so patients should have their potassium levels monitored closely. The earliest sign of digoxin toxicity is GI distress, and later signs include bradycardia, vision changes, and arrhythmias. The apical pulse should be monitored for a full minute before administration, and the digoxin dose should not be given if the heart rate is less than 60 minutes beat per minute.

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