A brief talk on pioglitazone side effects

Pioglitazone can be an essential ally in the treatment of type 2 diabetes. In this video, we explain how this medication helps control blood sugar levels by improving the sensitivity of cells to insulin, allowing your body to use insulin more efficiently. In addition, we provide key tips on the importance of following medical instructions for dosing and being aware of possible side effects and contraindications.

#Type2Diabetes #SugarControl #Health #Pioglitazone #DiabetesCare

Pioglitazone is a thiazolidinedione that acts by activation of Peroxisome Proliferator Activated Receptor (PPAR) gamma. This drug increases the sensitivity of Insulin but it doesn't increase release of insulin.

#phenytoin #sodium #hydantoin

Phenytoin

Your Medication Phenytoin

Phenytoin is also known as the brand name: Dilantin and Phenytek

Phenytoin comes in a capsule, oral suspension, chewable tablet, and injection dosage forms.

Phenytoin is most commonly used for the control and prevention of seizures. No matter what your doctor had you taking it for phenytoin is usually taken by mouth three times daily. DO NOT stop taking phenytoin at once because it can actually increase your risk of having a seizure.

Standard dosing of phenytoin ranges from: 100 mg to 300 mg

Some common side effects with phenytoin include decreased coordination, involuntary eye movement, confusion, slurred speech.
Some less common side effects with phenytoin include unusual hair growth, changes in muscle tone, blood disorders, facial changes, constipation, dizziness, enlargement of lips, fever, headache, trouble falling asleep, joint pain, nausea, nervousness, sore or swollen gums, skin peeling, skin rash, tremors, twitching, vomiting, or yellowing of skin and eyes.

Do not take phenytoin if you are hypersensitive to phenytoin or other hydantoins.

While taking phenytoin, remember it is important to tell your doctor or pharmacist if you:

• Have signs of an allergic reaction, such as rash, itching, swelling, or tightness of the chest
• Have a severe skin rash that is reddish or purplish.
• Are pregnant or plan to become pregnant.
• Have yellowing of skin and eyes as this could be a sign of liver disease.

Simple and short presentation of the side effects of Phenytoin.

COMING SOON: Complete Course on Classification of Drugs

The content in the video is for the purpose of information and education ONLY and is NOT intended to replace or is NOT a substitute for professional medical diagnosis, treatment, or physician advise.
The information in the video or on this channel is for informational knowledge only. It should not be considered as specific to needs of a specific individual organisation or entity. This information is not the substitute of the advice and treatment by your doctor, medical specialist or pharmacist. Author of the video is not to be held liable for any discrepancy. The author or any other parties associated with the making of the videos on this channel does not assume any liability to any party for any loss or damage, that may directly or indirectly result from use of any information in the videos on this channel .

This video is about problems with chronic Dilantin (phenytoin) use. Often these issues aren't covered when someone is on the medicine.

Phenytoin 3 side effects Every Pharmacist must know

🚨 FDA Questions Phenylephrine’s Effectiveness! 🤧💊

Phenylephrine, a common OTC decongestant, is under scrutiny for not working effectively when taken orally due to poor absorption and first-pass metabolism in the liver. The FDA advisory committee has reviewed studies suggesting that it provides little to no relief, leading to discussions about its removal from the market.

🔹 Why is phenylephrine ineffective?
🔹 What are better alternatives for nasal congestion?
🔹 Will the FDA ban it completely?

Find out everything you need to know in this deep dive! ⬇️

#Phenylephrine #FDABan #NasalCongestion #ColdMedicine #Decongestant #HealthNews #MedicalFacts #Pharmacology #DoctorExplains

Injection phenylephrine | indications, contra indication | drug dilution and dose calculations @anaesthesiawithbabar2576

Injection phenylephrine | indications, contra indication | drug dilution and dose calculations @anaesthesiawithbabar2576
#phenylephrine
#vasoconstriction
#alphaagonist
Drug use for #spinal #shock
#septic shock #neurogenic shock

In this video, we delve into the details of phenylephrine, a potent vasopressor used to treat hypotension and vasodilatory shock. We explore its mechanism of action, dosages, side effects, contraindications, nursing considerations, drug interactions, and pharmacokinetics. Viewers are encouraged to grasp the essential information for safe and effective administration of phenylephrine.

Here, I described the uses and side effects of Phenylephrine..

When it is that time of year and you have a stuffy nose that won’t clear up, over the counter medications at your pharmacy can help. Today I’m going to talk about phenylephrine, also known as Sudafed PE.

Phenylephrine, sold under the name brands Sudafed PE and Sudogest PE, is a nasal decongestant used to treat nasal congestion caused by a cold, infection, or allergies. It is included in many combination OTC medications for cold, flu, and congestion.

Adults should take one tablet (10 mg) of phenylephrine every 4 hours as needed. Do not take more than six tablets (60mg) in one day and do not take for more than 7 days. Children younger than 12 take a smaller dose based on age.

Talk to your doctor or pharmacist before giving phenylephrine to a child. Like all OTC medications, follow the instructions on the package unless instructed otherwise by your doctor.

Common side effects of phenylephrine include anxiety, dizziness, restlessness, difficulty sleeping, or an upset stomach. Taking this medicine with food if you have an upset stomach. Tell your doctor if you experience signs of high blood pressure, including bad headache, dizziness or passing out. Other symptoms to tell your doctor about include chest pain, fast heartbeat, nervousness, or shakiness.

If you have high blood pressure, thyroid problems, take medicine for mood (including depression and anxiety), or are pregnant or breastfeeding, be sure to talk to your doctor or pharmacist before taking phenylephrine. Do not take this medication if you are allergic to phenylephrine or any related drug, including pseudoephedrine. If you are 65 years or older, check with your doctor or pharmacist before use, as you could be more predisposed to the adverse effects of phenylephrine.

Phenylephrine, or Sudafed PE, is a nasal decongestant you can take it for a stuffy nose. There are other medications available to help when you have a cold, allergies, or a sinus infection. Your pharmacist will be able to help you choose the best over the counter option for you!

To end our Seasonal Allergy series, we're diving into pseudoephedrine products. Are they the best option for allergy season? Watch now to find out!

A Food and Drug Administration Committee has confirmed that many over-the-counter cold medications don't actually work.

Phenylephrine is used to relieve nasal discomfort caused by colds, allergies, and hay fever. It is also used to relieve sinus congestion and pressure. Phenylephrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery.

Phentermine 37.5 mg tablets are used for weight loss and it is anorectic agent.



#phentermine

Phentermine can be adjusted in many ways to make it more effective and to decrease the risk of regaining weight that has been lost.

Phentermine is one of the weight loss medications used for short-term periods to treat exogenous obesity in people with a body mass index greater than 30 kg per square meter. It can be used for up to 12 weeks to produce significant weight loss.

Phentermine acts by increasing sympathetic stimulation in the hypothalamus of the brain. It increases neuronal transmission of norepinephrine, which then controls appetite centers within the brain.



Disclaimer: The video is intended for educational purposes only, and all the information provided here is neither a substitute for medical advice nor is it recommended for diagnosis or treatment. All efforts are made to provide accurate and error-free information, but the content is variable from time to time due to advances in medical research. Always seek professional medical advice in case of any medical queries, and the videos on this platform do not provide any such suggestions or professional advice.

#phentermine

Phentermine is an FDA approved oral therapy that assists in short-term weight loss in combination with diet and exercise. Phentermine belongs to the appetite suppressing family and is a weak relative of amphetamine. Phentermine may be appropriate when the BMI – body mass index – exceeds 30 or 27 in the presence of other cardiovascular risk factors .

Phentermine is inappropriate for those who desire to lose a few pounds. In selected individuals it should be administered on hour or two before or after breakfast. A split dose of 18.75 mg before breakfast and dinner is also acceptable. Since phentermine functions as a stimulant, a bedtime dose risks insomnia.

Therapy may continue for a maximum of 12 weeks. Unfortunately a regain of weight generally occurs in the absence of a continuous low calorie diet. weight regain occurs after discontinuation of therapy. The greatest weight loss occurs in the first several weeks of therapy. Effectiveness of Phentermine is lost beyond 12 weeks of use.

Contraindications against use of phentermine include coronary artery disease, arrhythmia, uncontrolled blood pressure and heart failure. Hyperthyroidism, glaucoma, an agitated state and pregnancy also exclude Phentermine eligibility. Phentermine should not be prescribed to those with a history of drug abuse.

Generally well tolerated, adverse effects of phentermine include dry mouth, unpleasant taste, diarrhea or constipation. Hives or urticaria, hair loss and erectile dysfunction may also develop. Symptoms of acute phentermine overdose present as restlessness, tremor, panic attacks, confusion and hallucinations. Insomnia, irritability, hyperactivity and psychosis reminiscent of schizophrenia may indicate chronic toxicity.

00:00 - Start
00:17 - What Is Phentermine?
02:08 - Potential Side Effects
04:50 - Precautions & Best Practices

In this video, I review the medication phentermine. Phentermine, which is sold under the brand names Adipex and Lomaira, is a prescription-only appetite suppressant used as part of a weight loss program.

As with any medication, there are potential side effects to be aware of with phentermine. These may include dizziness, headache, dry mouth, constipation, and increased heart rate. If you experience severe or persistent side effects, you must contact your doctor immediately.

There are also certain precautions you should be aware of before taking phentermine. For example, it should not be taken by individuals with a history of heart disease or high blood pressure or by pregnant or nursing women. It is also important to inform your doctor of any other medications you are currently taking, as phentermine may interact with certain drugs.

Effets Secondaire du Phénobarbital sur un Chihuahua épileptique - 5ième journée

Phenobarbital is a medication that belongs to the class of drugs known as barbiturates. It has been used for many years as an anticonvulsant, sedative, and hypnotic agent. Its primary use is in the treatment of epilepsy and seizures.

Phenobarbital is commonly prescribed to control and prevent various types of seizures, including generalized tonic-clonic seizures, partial seizures, and febrile seizures. It is also used as a maintenance therapy to prevent recurrent seizures in individuals with epilepsy.

The dosing guidelines for phenobarbital vary depending on the patient's age, weight, and medical condition. The medication is available in different formulations, including tablets, capsules, and liquid. The dosage is typically started low and gradually increased until the desired therapeutic effect is achieved. It is important to follow the healthcare provider's instructions and never exceed the prescribed dose.

As with any medication, phenobarbital may cause certain side effects. Common side effects include drowsiness, dizziness, confusion, and sedation. These effects are more likely to occur when starting the medication or when the dose is increased. Individuals taking phenobarbital may also experience gastrointestinal disturbances such as nausea, vomiting, and constipation. Other potential side effects include skin rashes, allergic reactions, and changes in mood or behavior.

It is important to note that phenobarbital can interact with other medications and substances, including alcohol. It may also have sedative effects that can impair cognitive and motor functions, so it is advised to avoid activities that require mental alertness or coordination until the individual's response to the medication is known.

In conclusion, phenobarbital is primarily used for the treatment of epilepsy and seizures. It is an effective anticonvulsant, but it may cause side effects such as drowsiness, dizziness, and gastrointestinal disturbances. It is important to follow the prescribed dosing guidelines and be aware of potential drug interactions. As always, it is crucial to consult with a healthcare provider for personalized advice and guidance.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately."

Phenobarbital belongs to a group of medicines called barbiturates. It is used to treat epilepsy and works by stabilising electrical activity in the brain.

This video was made by Anh Ho , 2024 Pharmacist Candidate. He will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters

Phenobarbital is the most commonly used drug in the earlier days. It is the most common drug available to treat convulsions in children and in older people. Phenobarbital is less commonly used compared to older days especially in children less than 3 months of age. Of course we will use less commonly. We will use only if they are not responding to other newer drugs and there are lot of side effects, then only we consider this Phenobarbitone. Rivotrail can stop seizures in children. The main problem with rivotrail is that it causes lot of side effects like problems in concentration, especially in school going children, they can have decreased IQ in the future also. So if you are using Phenobarbital, you should be careful even though it is a good drug to stop seizure. But the side effects are more compared to the usage of benefits. Rivotrail is one of the drugs used commonly in treating epilepsy in children. This also can stop seizures but rivotrail alone we can’t use because it is just an adjuvant for other types of fits medicine also. The reason for it may stop the seizures temporality. The chance of recurrence after discontinuation of medication is very high and also if the seizures will stop temporarily even if you continue medication also, there is a chance of recurrence. So even though it stops temporarily, it cannot be used as a single medicine. Regarding the children who are suffering from seizures, the parent should be taken care of some of the important facts. They should consider and give medicine as per the doctor has advised. As per the doctor’s advice, they should have the medicines on regular times and regular frequency. They should not miss any medication. Even if they miss, they need to give medications immediately after remembering the next dose and if the child is getting medications, they should not discontinue suddenly or without advice from the doctor. They should not stop medication. Only if you stop medication, you should stop slowly after decreasing the dosage and if they are decreasing the dosage and if they are getting medications with seizures, they can have some behavioral problems in children especially drowsiness and sleepiness in the school or behavioral problems like aggressiveness and hyperactivity and this should be monitored with children and this should be reported to parents. Sometimes rarely problems with the kidney and the liver, they should be reported to the doctor. Regarding other precautions, better to avoid swimming in those children having epilepsy because during the episodes and during swimming if the child gets seizures, the chance of drowning is more. So these are some of the precautions parents should be aware when children are suffering from epilepsy.

Evidence linked at pharmacyjoe.com/episode399

#Cinnarizine#cyclizine#promethazine#Scopolamine# Granisetron#ondansetron#dolasetron#tropisetron#chlorpromazine#perphenazine#prochlorperazine#trifluoperazine#Metoclopramide#Domperidone#CTZ#nausea#vomiting#motionsickness#vestibulardisorders#Menière’sdisease#morningsicknessofpregnancy#antiemetic The Vomiting center has receptors for
Nurokinin 1 NK-1,
Cannabinoids CB-1,
serotonin 5-HT3,
dopamine D2,
muscarinic M1
and histamine H1 receptors.
The vomiting center can be activated by afferent fibers
arising from the gastrointestinal track,
Chemoreceptor trigger zone CTZ,
Cerebral cortex and vestibular apparatus.
The CTZ or Chemo receptor trigger zone, is located at the end of fourth ventricle.
CTZ have receptor of serotonin 5-HT3, dopamine D2, muscarinic M1 receptors.
It lies outside of blood brain barrier and stimulate vomiting center in response to
blood borne substances including cytotoxic cancer chemotherapy drugs.
The excessive vestibular stimulation in motion sickness activates the vomiting center
via cholinergic and histaminergic nerve fibers that projected through vestibulocerebellar region of cerebellum.
The irritation of gastric mucosa by chemotheraperautic agents, endogenous toxin and poison leads to
secretion of 5-HT which activate 5-HT3 receptor and this stimuli travel from the gastrointestinal tract
via the nucleus tractus solitarius (NTS) to stimulate vomiting center in the medulla.
Emesis by psychological stimuli such as fear, dread, or obnoxious sights and odors is mediated in
cerebral cortex,
this concept is poorly understood yet.
Nurokinin 1 NK-1, Cannabinoids CB-1 and Histamine could be responsible this effect.
Now we will see the site of action of various antiemetic drugs
Antihistaminic
Antihistaminic antiemetic includes
Cinnarizine, cyclizine and promethazine
Antihistaminic drugs blocks muscarinic M1 receptors or histamine H1 receptors or both types of receptors
in the vestibular tracts that project to the vomiting center and in the CTZ.
Antihistaminic drug Cyclizine is used in motion sickness.
cinnarizine is used in motion sickness and vestibular disorders such as Menière’s disease)
promethazine is used in severe morning sickness of pregnancy.

Antimuscarinics
Antimuscarinics drug Scopolamine is used in motion sickness.
It causes blocking of muscarinic M1 in vestibular tracts.

5-HT3 receptors antagonist
5-HT3 receptors antagonist includes Granisetron, ondansetron, dolasetron, tropisetron and palonsetron.
They are particular value in preventing and treating the vomiting and nausea.
commonly encountered postoperatively as well as that caused by radiation therapy or administration of cytotoxic drugs such as cisplatin.
They prevent emesis by competitively blocking 5-HT3

CBS2’s Dr. Max Gomez reports.