Dangerous Side Effects
Dapagliflozin (brand name Forxiga) is a Sodium-glucose co-transporter 2 (SGLT2) inhibitor and is prescribed for adults with type 2 diabetes mellitus to improve their diabetic control when diet and exercise alone are not enough for good control. It can also be used to treat heart failure and chronic kidney disease (CKD).
This video will explain everything you needs to know about SGLT2 inhibitors, including common and uncommon side-effects such as Thrush, Fourniers Gangrene and Diabetic Ketoacidosis (DKA). We will also give you advice about how to manage some of the side-effects.
https://youtu.be/h3OWgz45fIM
https://youtu.be/qWiw3rMhYvI
https://youtu.be/rnfJrCyqtJA
In Diabetes, SGLT2 inhibitors are given on their own in patients for whom the use of metformin is considered inappropriate due to reasons of intolerance or contraindications. SGLT2 inhibitors can also be given with other glucose-lowering drugs, including insulin, when these drugs do not provide adequate diabetic control.
The SGLT2 inhibitor-containing medicines marketed in the UK are Forxiga▼ (dapagliflozin), Xigduo▼ (dapagliflozin and metformin), Jardiance▼ (empagliflozin), and Synjardy▼ (empagliflozin and metformin) Edistride ▼(dapagliflozin),
Ebymect ▼(dapagliflozin/metformin), Qtern ▼(dapagliflozin/ saxagliptin), Invokana▼ (canagliflozin), Vokanamet▼ (canagliflozin/metformin), Glyxambi▼ (empagliflozin/linagliptin), Steglatro▼ (ertugliflozin), Segluromet▼ (ertugliflozin/metformin), and Steglujan▼ (ertugliflozin/sitagliptin)
#dapagliflozin #sglt2inhibitors #type2diabetes
Timeline:
00:00 Introduction
01:03 What is Dapagliflozin?
02:16 How do you take it?
02:51 What are the common side-effects?
06:11 What are the uncommon side-effects?
09:10 What are the cautions with other medicines?
10:39 Do you stop taking SGLT2 inhibitors if you become unwell?
11:19 What is the 'Sick Day Guidance'?
Clinical data:
UK Drug Safety update on SGLT2 inhibitors and reports of Fournier’s gangrene:
https://www.gov.uk/drug-safety....-update/sglt2-inhibi
and the FDA Safety announcement:
https://www.fda.gov/drugs/drug....-safety-and-availabi
UK Drug Safety update about SGLT2 inhibitors and Risk of Diabetic Ketoacidosis
https://www.gov.uk/drug-safety....-update/sglt2-inhibi
UK Drug Safety Update on SGLT2 inhibitors and increased Risk of Lower-limb Amputation (mainly toes):
https://www.gov.uk/drug-safety....-update/sglt2-inhibi
Disclaimer: The videos posted will be for general informational purposes only. They should not be used to self-diagnose or a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. You should not make any changes to your health regimen or diet before first consulting a doctor.
Let's cover the side effects of iron supplements. Including some of the more common side effects as well as ways to minimize the chances of side effects occuring.
I also talk about the different types of iron supplements, how fast and how much of each is absorbed in your system which can also effect side effects occurring.
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Ferrous Gluconate: https://amzn.to/44sjzWN
Chapters:
0:00 Introduction to iron supplements and problems with information
0:39 Most common iron supplement side effects
0:57 12 ways to decrease side effects from happening
6:45 What is the best iron supplement to take?
References:
1) https://pubmed.ncbi.nlm.nih.gov/15531698/
2) https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC64161
3) https://www.sciencedirect.com/....science/article/pii/
DISCLAIMER:
Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for advice provided by a doctor or other qualified healthcare professional.
Always seek the advice of your physician or other qualified health care professional with questions you may have regarding your medical condition.
Although all measures are taken to ensure that the contents of the YouTube channel is accurate and up-to-date, all information contained on it is provided ‘as is’.
I make no warranties or representations of any kind concerning the accuracy or suitability of the information contained on this channel.
Curtis Alexander may at any time and at its sole discretion change or replace the information available on this channel.
To the extent permitted by mandatory law, Curtis Alexander shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.
I sometimes provide links to products or services that I know, like and trust. In some cases these may be affiliate links where I earn from qualifying purchases.
Ferrous Sulfate is the best form of iron to take for anaemia - receipts provided! Side effects are common but easy to avoid.
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Ever find yourself lost in an endless sea of notifications, falling down the rabbit hole of social media, or maybe reaching for just one more sweet treat more often than you'd like? If you can relate, then you may be interested in a topic that's got people talking lately - the 'Dopamine Detox.' What is it? How do you do it? What’s the results of it? Is it backed by science? These are the questions that will be answered in this video.
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References
Daniyal M, Javaid SF, Hassan A, Khan MAB. The Relationship between Cellphone Usage on the Physical and Mental Wellbeing of University Students: A Cross-Sectional Study. Int J Environ Res Public Health. 2022 Jul 30;19(15):9352. doi: 10.3390/ijerph19159352. PMID: 35954709; PMCID: PMC9368281.
Graeme Eisenhofer and others, Substantial Production of Dopamine in the Human Gastrointestinal Tract, The Journal of Clinical Endocrinology & Metabolism, Volume 82, Issue 11, 1 November 1997, Pages 3864–3871, https://doi.org/10.1210/jcem.82.11.4339
Wacks Y, Weinstein AM. Excessive Smartphone Use Is Associated With Health Problems in Adolescents and Young Adults. Front Psychiatry. 2021 May 28;12:669042. doi: 10.3389/fpsyt.2021.669042. PMID: 34140904; PMCID: PMC8204720.
Chen, Chunmei et al. “The relationship between self-esteem and mobile phone addiction among college students: The chain mediating effects of social avoidance and peer relationships.” Frontiers in psychology vol. 14 1137220. 13 Apr. 2023, doi:10.3389/fpsyg.2023.1137220
Want to know more about mental health and self-improvement? On this channel I discuss topics such as bipolar disorder, major depression, anxiety disorders, attention deficit disorder (ADHD), relationships and personal development/self-improvement. I upload weekly. If you don’t want to miss a video, click here to subscribe. https://goo.gl/DFfT33
Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.
In this episode of I CARE FOR YOUR BRAIN with Dr. Sullivan, board certified neuropsychologist Dr. Karen D. Sullivan discusses her top 5 concerns regarding the usage of the prescription drug Ambien and its effects on brain health.
The article Dr. Sullivan mentions is available at: https://www.umassmed.edu/globa....lassets/psychiatry/c
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The video contains a simple and visual explanation of how Canagliflozin Empagliflozin and Dapagliflozin, SGLT2 inhibitors, work to get the kidneys to excrete glucose into the urine. We cover some basics about how the nephron works and look in detail at the action of SGLT2 inhibitors on the sodium-glucose transport protein 2 (SGLT2) in the proximal tubule. We also talk about the indications and adverse effects.
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If you have Iron Deficiency Anemia then this video may help you more than any other because so many people (including doctors) don't know this important fact. Tannins block your bodies ability to absorb Iron when consumed before, during, after a meal rich in iron. Don't let tannins keep you Iron Deficient. Avoid tannins so you can absorb more of the iron your body needs!
In addition to the foods mentioned in this video, Avocados and Olives also contain tannins...
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---Research---
https://sci-hub.se/https://doi.....org/10.1093/ajcn/37
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC59983
https://www.tandfonline.com/do....i/abs/10.1080/104086
https://pubmed.ncbi.nlm.nih.gov/18400710/
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Ken D Berry, MD, is a Family Physician and has been practicing Family Medicine in Tennessee for over 20 years, having seen over 25,000 patients in his career so far.
Consult your doctor. Don't use this video as medical advice.
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Any information on diseases and treatments available at this channel is intended for general guidance only and must never be considered a substitute for the advice provided by your doctor or other qualified healthcare professional.
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What Are Ampicillin's Side Effects? In this informative video, we will discuss the potential side effects of ampicillin, a commonly prescribed antibiotic for bacterial infections. Understanding these side effects is essential for first responders as it aids in making informed decisions during emergencies. We will cover both common and serious side effects that may arise from ampicillin use. From gastrointestinal issues to more severe allergic reactions, knowing what to look for can help you provide better patient care.
We will also explore the necessary steps to take if a patient exhibits signs of an allergic reaction, including anaphylaxis. Additionally, we will highlight the importance of thorough documentation and communication with hospital staff. This knowledge is not only beneficial for first responders but also crucial for ensuring patient safety in urgent situations.
Join us to learn more about how to manage the side effects of ampicillin effectively. Don't forget to subscribe to our channel for more helpful information on first responders medicine and emergency care.
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Please note that all content is for informational purposes only and should not be considered medical advice. Always conduct your own research and consult with professionals when necessary. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
Why Is Oxybutynin Not Good For Elderly? In this informative video, we will discuss the implications of using oxybutynin in elderly patients. Oxybutynin is commonly prescribed for overactive bladder, but it comes with a range of side effects that can be particularly concerning for older adults. We will cover the various side effects associated with this medication, including how it may affect cognitive function and overall health.
We will also highlight the risks of interactions with other medications that seniors often take and how these interactions can lead to increased side effects. Understanding these factors is essential for caregivers and family members who want to ensure the well-being of their elderly loved ones.
Additionally, we’ll provide insights into alternative treatment options for overactive bladder that may be safer for older adults. It's important to have open conversations with healthcare providers about the best treatment plans tailored to individual needs.
Join us in this video as we break down the important considerations surrounding oxybutynin use in the elderly. Stay informed and equipped to make the best decisions for your loved ones. Don’t forget to subscribe to our channel for more helpful content on elder care!
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Please note that our videos are for informational purposes only and do not constitute professional advice. We encourage you to conduct your own research and consult with relevant professionals when necessary. Thank you for being a part of our network, and we look forward to supporting you!
Dr. Pagnani of Rittenhouse Psychiatric Associates discusses Ambien (Zolpidem) a sedative that is FDA approved for insomnia. Ambien has abuse potential and is a controlled substance, and should only be taken under the direct supervision of a medical provider, after thorough consent and discussion of risks and benefits. Treatment with Ambien should be short-term when possible, and individuals should only take the lowest effective dose. Additionally, individuals may benefit from considering non-benzodiazepine or non-benzodiazepine derivative medications before a trial with a medication like Ambien (Zolpidem). Some notable side effects with Ambien (Zolpidem) include sleep walking (which can be very dangerous), excessive sedation, incoordination, respiratory depression, tolerance, physiological dependence and others. Individuals should not combine alcohol with zolpidem.
Dr. Pagnani is the founder and medical director of Rittenhouse Psychiatric Associates, an Instructor at The Johns Hopkins Hospital for the Department of Psychiatry, he supervises psychiatric residents at Jefferson Hospital, he serves on the Young Professional Board of Uplift, the Center for Grieving Children and he maintains a private practice of Psychiatry in Philadelphia where he sees patients for one-time psychiatric evaluations and second opinions. He is a licensed physician and surgeon in NJ, PA, NY, MD, DE, FL and CA and can provide consultations to individuals via HIPAA compliant Telehealth visits living in these locations.
Rittenhouse Psychiatric Associates is a private practice of psychiatry consisting of about 25 psychiatrists, psychiatric nurse practitioners and psychotherapists with physical locations in Philadelphia and Paoli, PA and serving all of PA, NJ, NY and FL virtually via HIPAA compliant tele-psychiatry. Individuals seeking not only evaluations but long-term psychiatric care, can contact Rittenhouse Psychiatric Associates directly.
These videos aim to increase awareness and discussion of mental health topics and to encourage struggling individuals to schedule an appointment directly with a mental health provider. Mental health needs to be normalized, and simply speaking about mental health topics openly, is an important first step.
Dr. Pagnani and Rittenhouse Psychiatric Associates are NOT advocating for or against the use of any mentioned psychiatric medications for any specific individual. Additionally, any side effects mentioned are not a complete list of potential side effects or contraindications to taking any mentioned medications, and all risks and benefits of a medication should be discussed with an individual’s provider at an appointment, before starting, stopping or making changes to a medication regimen.
This video is INFORMATIVE ONLY - NOT MEDICAL ADVICE.
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Neither aspirin nor warfarin is superior for preventing a combined risk of death, stroke, and cerebral hemorrhage inheart failure patients with normal heart rhythm, according to a landmark clinical trial published in the May 3, 2012, New England Journal of Medicine. Learn more at http://bit.ly/JDIx91.
In this video we talk about the supplement Niacin also known as Vitamin B3. Niacin is most commonly known for its positive effects with cholesterol and skin. The way Niacin works is by lower the levels of triglycerides and LDL, which is the bad cholesterol, and boosting levels of HDL, the good cholesterol.
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Meclizine is a histamine H1 antagonist used to treat nausea, vomiting, and dizziness associated with motion sickness.
In this video, let’s find found:
What is meclizine?
What is meclizine used for?
Contraindication
What are the side effects of taking meclizine?
How does meclizine work?
How to use meclizine?
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#meclizine #antihistamine #Bonine
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In this episode, I discuss a medication known as Benadryl (diphenhydramine).
My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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What Happens If You Overdose On Azelastine Nasal Spray? In this informative video, we discuss the potential effects of using too much Azelastine nasal spray, a medication commonly prescribed for allergic rhinitis in ear, nose, and throat medicine. While this spray is effective in managing allergy symptoms by blocking histamine, it's important to understand the risks associated with overuse. We will cover common side effects that may arise from excessive usage, such as a bitter taste, headaches, nasal discomfort, and drowsiness. Additionally, we’ll touch on more serious reactions that could occur and the importance of adhering to the prescribed dosage.
If you or someone you know has been using Azelastine nasal spray, this video is essential for understanding how to use it safely. We’ll also provide guidance on what to do if an overdose happens, including when to seek medical attention. Your health and well-being are our top priorities, so make sure to stay informed about the medications you use. Join us for this essential discussion, and don’t forget to subscribe to our channel for more helpful information on ear, nose, and throat health.
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Please note that all content on this channel is intended for informational purposes only and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and care. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
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In this video, Jonathan from the Institute of Human Anatomy discusses GLP-1 receptor agonists, a class of medications that includes Ozempic, Wegovy, as well as others that are used for type 2 diabetes and weight loss. We'll explore how these drugs work, their effectiveness, and the potential side effects, as well as considerations for their use in weight loss.
Disclaimer: The use of cadavers and all related content provided by Institute of Human Anatomy is strictly for educational purposes.
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Table of Contents:
0:00 - Intro: GLP-1 Receptor Agonists: Uses & Overview
1:11 - GLP-1 Receptor Agonists: Names, Including Ozempic, & How They Work
2:13 - The Role of Naturally Produced GLP-1
3:15 - GLP-1 Effects on Pancreas, Insulin & Glucagon
4:04 - How GLP-1 Receptor Agonists Mimic & Enhance GLP-1
5:22 - Semaglutide (Ozempic & Wegovy): Half-Life, Uses & Effectiveness
6:36 - Additional Benefits: Cardiovascular Risk Reduction
7:27 - Potential Side Effects: GI Issues, Fatigue & More
8:26 - Serious Side Effects: Pancreatitis, Gallbladder Issues & Others
9:22 - Muscle Loss: A Serious Consideration
9:45 - Financial Cost: Brand Name vs. Compounding Pharmacies
10:31 - Who Should Consider GLP-1 Receptor Agonists for Weight Loss
11:37 - Importance of Lifestyle Modifications: Diet & Exercise
13:33 - Dietary Considerations & the Role of Strength Training
14:25 - GLP-1 Agonists for Minor Weight Loss? Is It Worth It?
14:44 - The Risk of Weight Regain After Discontinuation
15:40 - Consult Your Healthcare Provider & Final Thoughts
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Common Questions:
What are GLP-1 receptor agonists?
How do GLP-1 receptor agonists work?
What are the benefits of GLP-1 receptor agonists like Ozempic?
What are the side effects of GLP-1 receptor agonists?
How effective are GLP-1 receptor agonists for weight loss?
Is Ozempic safe?
Who should consider using GLP-1 receptor agonists?
What is the role of diet and exercise when using GLP-1 receptor agonists?
What happens when you stop taking GLP-1 receptor agonists like Ozempic?
How much do GLP-1 receptor agonists cost?
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#GLP1 #Semaglutide #Ozempic #WeightLoss #Diabetes #Medication #Health #Anatomy
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